lactosyl lysosphingolipid

CAS No.
109785-20-8
Chemical Name:
lactosyl lysosphingolipid
Synonyms
Lactosyl-C18-sphingosine;lactosyl lysosphingolipid;lactosyl-beta-sphingosine;Lactosylsphingosine (d18:1);Lactosyl(ss) Sphingosine (d18:1);Lyso-Lactosylceramide (synthetic);Lactosyl(beta) Sphingosine (d18:1);D-lactosyl-1-1'-D-erythro-sphingosine;D-lactosyl-?1-1'-D-erythro-sphingosine;Lactosylsphingosine (d18:1) (synthetic)
CBNumber:
CB81329335
Molecular Formula:
C30H57NO12
Molecular Weight:
623.77308
MDL Number:
MFCD07374300
MOL File:
109785-20-8.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:19

lactosyl lysosphingolipid Properties

Boiling point 845.8±65.0 °C(Predicted)
Density 1.27±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility Chloroform:Methanol:Water (2:1:0.1): soluble; DMSO: soluble; Water: soluble
form A solid
pka 11.74±0.45(Predicted)
BRN 5680460

lactosyl lysosphingolipid price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 42137 Lactosylsphingosine ≥98.0% (TLC) 109785-20-8 1mg $118 2023-06-20 Buy
Sigma-Aldrich 42137 Lactosylsphingosine ≥98.0% (TLC) 109785-20-8 5mg $468 2023-06-20 Buy
Cayman Chemical 24868 Lactosylsphingosine (d18:1) ≥98% 109785-20-8 1mg $341 2024-03-01 Buy
Cayman Chemical 24867 Lactosylsphingosine (d18:1) (synthetic) ≥98% 109785-20-8 1mg $121 2024-03-01 Buy
TRC L165310 Lactosyl-C18-sphingosine 109785-20-8 2.5mg $205 2021-12-16 Buy
Product number Packaging Price Buy
42137 1mg $118 Buy
42137 5mg $468 Buy
24868 1mg $341 Buy
24867 1mg $121 Buy
L165310 2.5mg $205 Buy

lactosyl lysosphingolipid Chemical Properties,Uses,Production

Description

Lactosylsphingosine is a bioactive sphingolipid and a form of lactosylceramide that is lacking the fatty acyl group. Lyso-lactosylceramide (1-50 μM) reduces viability of human neutrophils in a concentration-dependent manner. Unlike lactosylceramide, Lactosylsphingosine has no effect on protein synthesis and cell proliferation in cardiomyocytes. Lactosylsphingosine is a precursor in the synthesis of lyso-ganglioside GM3. [Matreya, LLC. Catalog No. 2088]

Uses

Lactosyl(β) Sphingosine (d18:1) or D-lactosyl-β1-1′-D-erythro-sphingosine has been used as an internal standard for the quantification of psychosine?using tandem mass spectrometry. It may be used to screen lipids that rapidly and reversibly alter?transepithelial?electrical resistance (TER) or tight junction (TJ) permeability in epithelial?tissue. It may also be used as a standard to determine the extent of recovery of lyso-neutral glycosphingolipids (lyso-n-GSLs) from the Sephadex column.

General Description

Lactosyl sphingosine?is a glycosylsphingosine (Lyso-GSL), which is found in bovine brain white matter extract.

Biochem/physiol Actions

Lactosyl sphingosine?exhibits better hemolytic activity than lysolecithin.

lactosyl lysosphingolipid Preparation Products And Raw materials

Raw materials

Preparation Products

lactosyl lysosphingolipid Suppliers

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lactosyl lysosphingolipid D-lactosyl-1-1'-D-erythro-sphingosine 2-[6-[(E,2S,3R)-2-amino-3-hydroxyoctadec-4-enoxy]-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Lactosylsphingosine (d18:1) Lyso-Lactosylceramide (synthetic) Lactosyl-C18-sphingosine Lactosylsphingosine (d18:1) (synthetic) Lactosyl(ss) Sphingosine (d18:1) Lactosyl(beta) Sphingosine (d18:1) β-D-Glucopyranoside, (2S,3R,4E)-2-amino-3-hydroxy-4-octadecen-1-yl 4-O-β-D-galactopyranosyl- Lacsph d18:1 (Galb1,4GlcbSphingolipids) lactosyl-beta-sphingosine D-lactosyl-?1-1'-D-erythro-sphingosine 109785-20-8 C30H57NO12