lithospermic acid B
- CAS No.
- 121521-90-2
- Chemical Name:
- lithospermic acid B
- Synonyms
- Danfensuan B;Salvialic acid B;Salvianolate;alvianolic acid B;Lithospermic acid B;*Fentanyl Impurity 18;Extra Cas No: 115939-25-8;Salvianolic Acid B (25 mg);Salvianolic acid B Cas 115939-25-8;Salvianolic acid B, froM Salvia Miltiorrhiza
- CBNumber:
- CB81330946
- Molecular Formula:
- C36H30O16
- Molecular Weight:
- 718.61
- MDL Number:
- MFCD23115783
- MOL File:
- 121521-90-2.mol
- MSDS File:
- SDS
| Melting point | 98-110°C |
|---|---|
| Boiling point | 1020.3±65.0 °C(Predicted) |
| Density | 1.637±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | H2O: ≥5mg/mL |
| form | powder |
| pka | 2.77±0.10(Predicted) |
| color | white to tan |
| optical activity | [α]/D +95 to +115°, c = 1 in methanol |
| InChIKey | SNKFFCBZYFGCQN-VWUOOIFGSA-N |
| FDA UNII | C1GQ844199 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DF6492107 | |||||||||
| HS Code | 29329990 | |||||||||
| NFPA 704 |
|
lithospermic acid B price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 49724 | Salvianolic acid B analytical standard | 121521-90-2 | 10mg | $410 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1609818 | Salvianolic acid B United States Pharmacopeia (USP) Reference Standard | 121521-90-2 | 25mg | $365 | 2024-03-01 | Buy |
| Cayman Chemical | 9001577 | Salvianolic Acid B ≥95% | 121521-90-2 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 9001577 | Salvianolic Acid B ≥95% | 121521-90-2 | 5mg | $100 | 2024-03-01 | Buy |
| Sigma-Aldrich | Y0001559 | Salvianolic acid B European Pharmacopoeia (EP) Reference Standard | 121521-90-2 | y0001559 | $153 | 2024-03-01 | Buy |
lithospermic acid B Chemical Properties,Uses,Production
Chemical Properties
Yellow Solid
Uses
Salvianolic acid A (Sal A) and salvianolic acid B (Sal B) were isolated and purified from the crude extract of Salvia miltiorrhiza. Antioxidant activities of Sal A and Sal B were also evaluated and the ABTS results showed that Sal A and Sal B exhibited high total antioxidant activities, their EC50 values were 1.35 0.00 and 1.43 0.01 .mu.g/mL. This compound always contains a significant amount of residual solvent.
Definition
ChEBI: Salvianolic acid B is a member of the class of 1-benzofurans that is an antioxidant and free radical scavenging compound extracted from S. miltiorrhiza It has a role as a plant metabolite, an anti-inflammatory agent, an antioxidant, a hypoglycemic agent, an osteogenesis regulator, an apoptosis inducer, a hepatoprotective agent, a neuroprotective agent, a cardioprotective agent, an autophagy inhibitor, an antidepressant and an antineoplastic agent. It is a polyphenol, a member of 1-benzofurans, an enoate ester, a dicarboxylic acid and a member of catechols.
General Description
Salvianolic acid B is one of the main water soluble bioactive components of Salvia miltiorrhiza medicinal plant, the root of which is used in the treatment of dysmenorrhea, coronary heart disease, chronic renal failure, cerebrovascular disease, hypertension, and cytotoxicity against human tumor cell lines.
Biochem/physiol Actions
Salvianolic acid B is a cell protective antioxidant and free radical scavenger being investigated for a variety of conditions from ischemic heart disorders to Alzheimer′s disease. Several mechanisms of action have been proposed including EGFR, PDGF and MMP-9 inhibition and inhibition of the TGF-β1/Smads and NF-κB signaling pathways. Salvianolic acid B acts as scavengers of reactive oxygen species, reduces the adherence of leukocytes to endothelial cells, inhibits matrix metalloproteinases and inflammation. It has cardioprotective effects as it reduces lipid peroxidation in damaged cardiac tissue and decreases the leakage of lactic acid dehydrogenase.
target
SIRT
lithospermic acid B Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Jiangsu Yongjian Pharmaceutical Co.,Ltd | +86-0523-80183620 +86-17701422015 | 982552664@qq.com | China | 258 | 58 |
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 | info@binbobiological.com | China | 311 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| Speranza Chemical Co., Ltd. | +86-86-075521030354 +8618688942810 | sophieliu@speranzachem.com | China | 723 | 55 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
View Lastest Price from lithospermic acid B manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-24 | Lithospermic Acid B
121521-90-2
|
US $0.00 / kg | 1kg | 10% 40% 50% 60% | 1000 kg | BINBO BIOLOGICAL CO.,LTD | |
 |
2022-05-13 | Lithospermic acid B | US $0.00 / g | 10g | 99.0% | 10tons | Wuhan Godbullraw Chemical Co.,ltd | |
 |
2020-02-11 | salvianolic acid B
121521-90-2
|
US $9.80 / KG | 1g | ＞98% | 20 tons | Career Henan Chemical Co |
-
- Lithospermic Acid B
121521-90-2
- US $0.00 / kg
- 10% 40% 50% 60%
- BINBO BIOLOGICAL CO.,LTD
-
- Lithospermic acid B
- US $0.00 / g
- 99.0%
- Wuhan Godbullraw Chemical Co.,ltd
-
- salvianolic acid B
121521-90-2
- US $9.80 / KG
- ＞98%
- Career Henan Chemical Co