ANTI-DESMIN
- CAS No.
- Chemical Name:
- ANTI-DESMIN
- Synonyms
- Anti-CSM2;Anti-CSM1;Anti-CMD1I;ANTI-DESMIN;Anti-FLJ39719;Anti-FLJ12025;Anti-FLJ41013;Anti-FLJ41793;MS X ANTI-DESMIN;ANTI-HUMAN DESMIN
- CBNumber:
- CB8136147
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00162258
- MOL File:
- Mol file
ANTI-DESMIN price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB4500642 | Anti-Desmin antibody produced in rabbit affinity isolated antibody | 100μg | $506 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB2500306 | Anti-Desmin antibody produced in goat | 100μg | $568 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB2100564 | Anti-DES antibody produced in rabbit affinity isolated antibody | 100μL | $524 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA018803 | Anti-DES antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $547 | 2024-03-01 | Buy | |
| Sigma-Aldrich | D8281 | Anti-Desmin antibody produced in rabbit whole antiserum | 0.2mL | $344.4 | 2024-03-01 | Buy |
ANTI-DESMIN Chemical Properties,Uses,Production
Uses
Anti-Desmin antibody produced in rabbit has been used in:
- immunohistochemistry of zebrafish intestines sections
- immunodetection in fish embryo samples
- immunolabeling of myofibers
General Description
Desmin is an intermediate filament protein found mainly in skeletal, cardiac, and smooth muscle cells. It acts as a marker for tumor origin. It also facilitates mechanical support for muscles, mitochondrial localization, myofibrillogenesis, gene expression regulation, and intracellular signalling. Anti-desmin antibody can be used for immunocytochemical localization of intermediate filaments in all types of muscle cells. It can also be used to stain a wide desmin band of 50,000 to 55,000 molecular weight using immunoblotting assays. Rabbit anti-desmin antibody reacts specifically with desmin in bovine, mouse, chicken and human.
Biochem/physiol Actions
Desmin plays a crucial role in providing mechanical strength to muscle tissues. Mutations in desmin gene contributes to imbalance in skeletal proteins, resulting in desminopathies. Missense mutations in desmin gene leads to hypertrophic cardiomyopathy and systemic myopathy. Mutations in desmin gene impairs the stability of intermediary filaments in cardiomyocytes, contributing to pathophysiology of cardiac diseases.
ANTI-DESMIN Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-DESMIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |