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LUPULONE

CAS No.
468-28-0
Chemical Name:
LUPULONE
Synonyms
lupulon;b’’-acid;LUPULONE;B-LUPULIC ACID;lohexadien-1-one;BETA-BITTER ACID;BETA-LUPULIC ACID;Lupulone beta-acid;Coclaurine Impurity 3;1-Amino-8-naphthol-3,5-disulfonic acid
CBNumber:
CB8136556
Molecular Formula:
C26H38O4
Molecular Weight:
414.58
MDL Number:
MFCD00075970
MOL File:
468-28-0.mol
MSDS File:
SDS
Last updated:2023-05-21 10:59:17

LUPULONE Properties

Melting point 93℃
Boiling point 453.43°C (rough estimate)
Density 1.045±0.06 g/cm3 (20 ºC 760 Torr)
vapor pressure 0Pa at 20℃
refractive index 1.4840 (estimate)
storage temp. Store at -20°C
solubility Methanol: slightly soluble
form A solid
pka 4.50±1.00(Predicted)
Water Solubility 1g/L at 20℃
Stability Hygroscopic
LogP 4.5 at 20℃
EWG's Food Scores 1
FDA UNII B7425USG94

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H312-H302-H319-H317
Precautionary statements  P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P280-P302+P352-P312-P322-P363-P501-P264-P280-P305+P351+P338-P337+P313P-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
Hazard Codes  T
Risk Statements  25
Safety Statements  45
RIDADR  2811
RTECS  OK5950000
HazardClass  6.1(b)
PackingGroup  III
Toxicity LD50 in mice, rats (mg/kg): 525, 100 orally (Hnsel, Wagener)

LUPULONE price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 28481 Lupulone 468-28-0 1mg $44 2024-03-01 Buy
Cayman Chemical 28481 Lupulone 468-28-0 10mg $384 2024-03-01 Buy
Cayman Chemical 28481 Lupulone 468-28-0 5mg $202 2024-03-01 Buy
TRC L478000 Lupulone 468-28-0 10mg $185 2021-12-16 Buy
Biosynth Carbosynth FL74820 Lupulone 468-28-0 10mg $300 2021-12-16 Buy
Product number Packaging Price Buy
28481 1mg $44 Buy
28481 10mg $384 Buy
28481 5mg $202 Buy
L478000 10mg $185 Buy
FL74820 10mg $300 Buy

LUPULONE Chemical Properties,Uses,Production

Uses

Lupulone is a hop plant (Humulus lupulus L.) acid that inhibits tumorigenicity of hepatocellular carcinoma cells.

Definition

ChEBI: Lupulone is a beta-bitter acid in which the acyl group is specified as 3-methylbutanoyl. It has a role as an antimicrobial agent, an apoptosis inducer, an angiogenesis inhibitor and an antineoplastic agent. It is a conjugate acid of a lupulone(1-).

Purification Methods

Crystallise Lupulon from 90% MeOH, hexane or pet ether at low temperature. It has also been purified by chromatography through Kieselgel. [Wieland et al. Chem Ber 102 2012 1925, Riedl Chem Ber 85 692 1952, Beilstein 7 II 856, 7 III 4752, 7 IV 2866.]

LUPULONE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 62)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23556 58
Finetech Industry Limited
+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9589 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501 product@acmec-e.com China 33349 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76

View Lastest Price from LUPULONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Lupulone pictures 2020-01-13 Lupulone
468-28-0
US $1.00 / g 1g 95-99% 1ton Career Henan Chemical Co
LUPULONE pictures 2020-01-13 LUPULONE
468-28-0
US $1.00 / g 1g 99% 200kg Career Henan Chemical Co
  • Lupulone pictures
  • Lupulone
    468-28-0
  • US $1.00 / g
  • 95-99%
  • Career Henan Chemical Co
  • LUPULONE pictures
  • LUPULONE
    468-28-0
  • US $1.00 / g
  • 99%
  • Career Henan Chemical Co
2,4-cyclohexadien-1-one,3,5-dihydroxy-4-isovaleryl-2,6,6-tris(3-methyl-2-but 3,5-dihydroxy-2,6,6-tris(3-methyl-2-butenyl)-4-(3-methyl-1-oxobutyl)-2,4-cyc b’’-acid lohexadien-1-one lupulon LUPULONE B-LUPULIC ACID BETA-LUPULIC ACID BETA-BITTER ACID 3,5-DIHYDROXY-2,6,6-TRIS(3-METHYL-2-BUTENYL)-4-(3-METHYLBUTYRYL)-2,4-CYCLOHEXADIENONE Lupulone beta-acid 3,5-dihydroxy-2,6,6-tris(3-methylbut-2-enyl)-4-(3-methyl-1-oxobutyl)cyclohexa-2,4-dien-1-one 3,5-dihydroxy-2,6,6-tris(3-methylbuten-2-yl)-4-(3-methyl-1-oxobutyl)cyclohexa-2,4-dien-1-one 1-Amino-8-naphthol-3,5-disulfonic acid 5-Amino-4-hydroxy-1,7-naphthalenedisulfonic acid β-Bitter acid, β-Lupulic acid, 3,5-Dihydroxy-2,6,6-tris(3-methyl-2-butenyl)-4-(3-methylbutyryl)-2,4-cyclohexadienone 3,5-Dihydroxy-2,6,6-tris(3-methyl-2-butenyl)-4-(3-methyl-1-oxobutyl)-2,4-cyclohexadien-1-one 3,5-dihydroxy-2-(3-methylbutanoyl)-4,6,6-tris(3-methylbut-2-enyl)cyclohexa-2,4-dien-1-one 3,5-dihydroxy-2-isovaleryl-4,6,6-tris(3-methylbut-2-enyl)cyclohexa-2,4-dien-1-one 3,5-DIHYDROXY-2-(3-METHYLBUTANOYL)-4,6,6-TRIS(3-METHYLBUT-2-ENYL)CYCLOHE 2,4-Cyclohexadien-1-one,3,5-dihydroxy-2,6,6-tris(3-methyl-2-buten-1-yl)-4-(3-methyl-1-oxobutyl)- Coclaurine Impurity 3 468-28-0 Analytical Chromatography Product Catalog Alphabetic Analytical Standards Hop Compounds