napyradiomycin A1
- CAS No.
- 103106-24-7
- Chemical Name:
- napyradiomycin A1
- Synonyms
- WS-9558A;Napyradiomycin A;napyradiomycin A1;3,4a-Dichloro-6,8-dihydroxy-3,4,4a,10a-tetrahydro-2,2-dimethyl-10a-(3,7-dimethyl-2,6-octadienyl)-2H-naphtho[2,3-b]pyran-5,10-dione;2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-10a-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-3,4,4a,10a-tetrahydro-6,8-dihydroxy-2,2-dimethyl-, (3R,4aR,10aS)-
- CBNumber:
- CB81373343
- Molecular Formula:
- C25H30Cl2O5
- Molecular Weight:
- 481.41
- MDL Number:
- MFCD01712236
- MOL File:
- 103106-24-7.mol
SAFETY
Risk and Safety Statements
| HS Code | 29419000 |
|---|---|
| Toxicity | mouse,LD50,intraperitoneal,> 250mg/kg (250mg/kg),Journal of Antibiotics. Vol. 39, Pg. 487, 1986. |
napyradiomycin A1 price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 29215 | Napyradiomycin A1 | 103106-24-7 | 1mg | $189 | 2024-03-01 | Buy |
| TRC | N378705 | NapyradiomycinA1 | 103106-24-7 | 1mg | $165 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0013137 | NAPYRADIOMYCIN A 95.00% | 103106-24-7 | 5MG | $505.67 | 2021-12-16 | Buy |
napyradiomycin A1 Chemical Properties,Uses,Production
Description
Napyradiomycin A1 is a fungal metabolite originally isolated from C. rubra and has diverse biological activities. It is active against S. aureus, M. luteus, B. anthracis, C. bovis, and M. smegmatis (MICs = 1.56-12.5 μg/ml). Napyradiomycin A1 is an estrogen receptor antagonist (IC50 = 4.2 μM in rat uterine homogenates). It also inhibits mitochondrial NADH:ubiquinone oxidoreductase (complex I) and succinate:ubiquinone oxidoreductase (complex II) activities in bovine heart homogenates (IC50s = 20 and 9.7 μM, respectively).
Uses
Napyradiomycin derivatives have antibacterial and tumor properties. Napyradiomycin A1 is a secondary metabolite isolated from Streptomyces. It is also an antibacterial antibiotic and an inhibitor of mitochondrial complexes I and II.
Definition
ChEBI: Napyradiomycin A1 is a member of menaquinones.
napyradiomycin A1 Preparation Products And Raw materials
Raw materials
Preparation Products
napyradiomycin A1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Zhejiang Huida Biotech Co., LTD | 0571-89903882 13626641628 | jiangnan@huidabiotech.com | China | 3661 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |
| Zhejiang Huida Biotech Co., LTD | 0571-0571-89903882 15990081639 | sunshixuan@huidabiotech.com | China | 3705 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
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