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2-Hydroxypyridine

CAS No.
142-08-5
Chemical Name:
2-Hydroxypyridine
Synonyms
Pyridin-2(1H)-one;2-PYRIDONE;2(1h)-pyridinone;2-Pyridinol;Pyridin-2-one;2(1H)-PYRIDONE;2-PYRIDON;2-PYRIDOL;Pyridone-2;A-PYRIDONE
CBNumber:
CB8137755
Molecular Formula:
C5H5NO
Molecular Weight:
95.1
MDL Number:
MFCD00006268
MOL File:
142-08-5.mol
MSDS File:
SDS
Modify Date:2022-12-21 16:56:50

2-Hydroxypyridine Properties

Melting point 105-107 °C (lit.)
Boiling point 280-281 °C (lit.)
Density 1.39
refractive index 1.5939 (estimate)
Flash point 210 °C
storage temp. Sealed in dry,Room Temperature
solubility 450g/l
pka 0.75(at 20℃)
form Liquid
color Colorless to yellow to brown, darken on storage with no loss of purity
Water Solubility Soluble in water 450 g/L @ 20°C and ethanol, slightly soluble in benzene and ether.
BRN 105786
CAS DataBase Reference 142-08-5(CAS DataBase Reference)
FDA UNII 6770O3A2I5
NIST Chemistry Reference 2(1H)-Pyridinone(142-08-5)
EPA Substance Registry System 2(1H)-Pyridinone (142-08-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P330+P331+P310
Hazard Codes  Xi,Xn,T
Risk Statements  36/37/38-40-25
Safety Statements  26-36-37/39-22-45-36/37/39
RIDADR  UN2811
WGK Germany  3
RTECS  UV1144050
8
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29333990
Toxicity LD50 ipr-mus: 410 mg/kg TOXIA6 23,815,85
NFPA 704
1
2 0

2-Hydroxypyridine price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H56800 2-Hydroxypyridine 97% 142-08-5 25g $51.8 2023-01-07 Buy
Sigma-Aldrich 41152 2-Hydroxypyridine analytical standard 142-08-5 100mg $67.2 2022-05-15 Buy
TCI Chemical H0330 2-Hydroxypyridine >98.0%(GC)(T) 142-08-5 25g $23 2023-01-07 Buy
TCI Chemical H0330 2-Hydroxypyridine >98.0%(GC)(T) 142-08-5 250g $114 2023-01-07 Buy
Alfa Aesar A14522 2-Hydroxypyridine, 98% 142-08-5 25g $42.3 2022-04-27 Buy
Product number Packaging Price Buy
H56800 25g $51.8 Buy
41152 100mg $67.2 Buy
H0330 25g $23 Buy
H0330 250g $114 Buy
A14522 25g $42.3 Buy

2-Hydroxypyridine Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal

Uses

2-Hydroxypyridine is a bifunctional catalyst for a wide variety of acylation reactions, catalyst for generating β-oxopropyl carbonates from cyclic carbonates and alcohols and in the aminolysis of a polyglutamate. It is used in peptide synthesis.

Uses

Catalyst for generating β-oxopropyl carbonates from cyclic carbonates and alcohols and in the aminolysis of a polyglutamate.

Definition

ChEBI: 2-Hydroxypyridine is a monohydroxypyridine that is pyridine substituted by a hydroxy group at position 2. It has a role as a plant metabolite.

General Description

2-Hydroxypyridine, an enolic tautomer of 2-pyridone, belongs to the class of volatile organic compounds (VOCs).

Safety Profile

Moderately toxic by intraperitoneal and intravenous routes. A combustible liquid. When heated to decomposition it emits toxic vapors of NOx.

Purification Methods

Distil the pyridone under vacuum to remove coloured impurity, then recrystallise from *benzene, CCl4, EtOH or CHCl3/diethyl ether. It can be sublimed under high vacuum. [DePue et al. J Am Chem Soc 107 2131 1985, Beilstein 21/7 V 106.]

Global( 536)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21975 55
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418679 info@tnjchem.com China 2990 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
career henan chemical co
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Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47427 58

View Lastest Price from 2-Hydroxypyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Hydroxypyridine pictures 2023-01-28 2-Hydroxypyridine
142-08-5
US $0.00 / KG 100g 98%+ 100kg WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
2-Hydroxypyridine pictures 2022-09-28 2-Hydroxypyridine
142-08-5
US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
2-Hydroxypyridine pictures 2022-07-22 2-Hydroxypyridine
142-08-5
US $0.00-0.00 / kg 1kg 98%min 1000kg WUHAN FORTUNA CHEMICAL CO., LTD
1-Hydroxy-2-pyridine alpha-Pyridone Pyridone-2 AURORA KA-3075 A-PYRIDONE TIMTEC-BB SBB004392 a-Hydroxypyridine 1,2-dihydro-2-oxopyridine 1H-2-Pyridone 1h-pyridin-2-one 2-pyridinone 2-PYRIDON 2-PYRIDOL 2-oxopyridine 2-Pyridinol (2-hydroxy-pyridin) 2-hydroxypyridine (intermediate of benzoxazole) Diydrozylpyridine 2-Hydroxypyridine(2-Pyridinol) 2-Hydroxypyridine 2-Hydroxypyridine, 98+% 2-HYDROXYPYRIDINE pure 2-Pyridinol 2-Pyridone 2-PYRIDINOL FOR SYNTHESIS 2-hydroxypyridate 2(1H)-Pyridone, 2-Pyridinol 2-Hydroxypyridine,97% 2-Hydroxypyridine 97% 3-Fluoro-4-Methylbenzenethiol, >95% Levetiracetam EP Impurity C 2-Hydroxypyridine> 2-Hydroxypyridine, 98%, for synthesis Levetiracetam impurity C CRS 2-Hydroxypyridine ISO 9001:2015 REACH α-Pyridone α-Pyridone (Levetiracetam Impurity) Levetiracetam impurities520 Levetiracetam impurities12 Levetiracetam-3 Levetiracetam Impurity 3(Levetiracetam EP Impurity C) 2(1h)-pyridinone 2(1H)-PYRIDONE 2-PYRIDONE 2-Pyridinol Pyridin-2(1H)-one Pyridin-2-one 142-08-5 2762-00-6 148-08-5 C5H4NOH C5H5NO Building Blocks C5 Pyridines Heterocyclic Building Blocks Others Pyridines Pyridine Pyridines derivates