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thielavin B

CAS No.
71950-67-9
Chemical Name:
thielavin B
Synonyms
thielavin B;4-[(2,4-Dihydroxy-3,6-dimethylbenzoyl)oxy]-2-methoxy-3,5,6-trimethylbenzoic acid 4-carboxy-3-methoxy-2,5,6-trimethylphenyl ester
CBNumber:
CB81400007
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD11111623
MOL File:
71950-67-9.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

thielavin B Properties

storage temp. -20°C
solubility DMF: soluble; DMSO: soluble; Ethanol: soluble
form White to off-white powder.

thielavin B price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SMB00566 Thielavin B ≥95% (LC/MS-UV) 71950-67-9 1mg $705 2024-03-01 Buy
Cayman Chemical 18770 Thielavin B ≥95% 71950-67-9 500μg $364 2024-03-01 Buy
Cayman Chemical 18770 Thielavin B ≥95% 71950-67-9 2.5mg $1088 2024-03-01 Buy
Usbiological T5006-50A Thielavin B 71950-67-9 500ug $582 2021-12-16 Buy
Usbiological 467494 Thielavin B 71950-67-9 500ug $644 2021-12-16 Buy
Product number Packaging Price Buy
SMB00566 1mg $705 Buy
18770 500μg $364 Buy
18770 2.5mg $1088 Buy
T5006-50A 500ug $582 Buy
467494 500ug $644 Buy

thielavin B Chemical Properties,Uses,Production

Description

Thielavin B is a fungal metabolite that contains O-substituted salicylic acid. It inhibits cyclooxygenase, blocking both the conversion of arachidonic acid to Prostaglandin H2 (PGH2) and the conversion of PGH2 to PGE2 (, IC50s = 40 and 9 μM, respectively). Thielavin B also inhibits the reverse transcriptase of avian myeloblastosis virus, bacterial transglycosylases, and telomerase activity.

Uses

Thielavin B is a fungal metabolite of?Thielavia terricola that contains O-substituted salicylic acid. It is an inhibitor of viral reverse transcriptase and telomerase.

Uses

Thielavin B is a fungal metabolite closely related to thielavin A but reported to have a slightly different biochemical profile. Thielavins inhibit glucose-6-phosphatase. Thielavin B is a potent inhibitor of phospholipase C, and inhibits peptidoglycan formation and prostaglandin biosynthesis.

General Description

Natural product derived from fungal source.

thielavin B Preparation Products And Raw materials

Raw materials

Preparation Products

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thielavin B 4-[(2,4-Dihydroxy-3,6-dimethylbenzoyl)oxy]-2-methoxy-3,5,6-trimethylbenzoic acid 4-carboxy-3-methoxy-2,5,6-trimethylphenyl ester 71950-67-9