RUBRATOXINA
- CAS No.
- 22467-31-8
- Chemical Name:
- RUBRATOXINA
- Synonyms
- RUBRATOXINA;Rubratoxin A, PP2A inhibitor;10-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-(1-hydroxyheptyl)-1H-cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione;9-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-3,4,5,8,9,10-hexahydro-1,5-dihydroxy-4-(1-hydroxyheptyl)-3-oxo-1H-cyclonona[c]furan-6,7-dicarboxylic anhydride;1H-Cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione, 10-[(R)-[(2R)-3,6-dihydro-6-oxo-2H-pyran-2-yl]hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-[(1S)-1-hydroxyheptyl]-, (4S,5R,10R)-rel-
- CBNumber:
- CB81405198
- Molecular Formula:
- C26H32O11
- Molecular Weight:
- 520.528
- MDL Number:
- MFCD01735286
- MOL File:
- 22467-31-8.mol
| Product description | Number | Pack Size | Price |
| Rubratoxin A ≥95% | 19605 | 250μg | $299 |
| Rubratoxin A ≥95% | 19605 | 500μg | $507 |
| RubratoxinA | R701543 | 100μg | $365 |
| Rubratoxin A | 207390 | 250ug | $460 |
| RubratoxinA ≥95%(HPLC) | AG-CN2-0092-C500 | 500μg | $540 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazardous Substances Data | 22467-31-8(Hazardous Substances Data) | |||||||||
| NFPA 704 |
|
RUBRATOXINA price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19605 | Rubratoxin A ≥95% | 22467-31-8 | 250μg | $299 | 2024-03-01 | Buy |
| Cayman Chemical | 19605 | Rubratoxin A ≥95% | 22467-31-8 | 500μg | $507 | 2024-03-01 | Buy |
| TRC | R701543 | RubratoxinA | 22467-31-8 | 100μg | $365 | 2021-12-16 | Buy |
| Usbiological | 207390 | Rubratoxin A | 22467-31-8 | 250ug | $460 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CN2-0092-C500 | RubratoxinA ≥95%(HPLC) | 22467-31-8 | 500μg | $540 | 2021-12-16 | Buy |
RUBRATOXINA Chemical Properties,Uses,Production
Description
Rubratoxin A is a natural mycotoxin and competitive inhibitor of protein phosphatase 2A (PP2A; IC50 = 170 nM). It has no significant effect on several other phosphatases, including PP1, PP2B, and protein tyrosine phosphatase 1B. Rubratoxin A drives overphosphorylation of PP2A substrate proteins in cultured cells treated for three hours at 20 μM. It causes suppression of tumor metastasis and reduction of primary tumor volume in mouse xenografts.
Uses
Rubratoxin A is a potent and selective competitive PP2A inhibitor.
storage
-20°C
References
[1] SHUN-ICHI WADA. Rubratoxin A specifically and potently inhibits protein phosphatase 2A and suppresses cancer metastasis[J]. Cancer Science, 2010, 101 3: 743-750. DOI: 10.1111/j.1349-7006.2009.01438.x
RUBRATOXINA Preparation Products And Raw materials
Raw materials
Preparation Products
RUBRATOXINA Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32435 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3988 | 66 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6777 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24961 | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 028-81700200 13308200041 | 2851167782@qq.com | China | 11146 | 58 |
| Cayman Chemical Company | 800-364-9897 | sales@caymanchem.com | China | 6838 | 58 |
| Santa Cruz Biotechnology Inc | 021-60936350 | scbt@scbt.com | China | 6594 | 58 |
View Lastest Price from RUBRATOXINA manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-30 | Rubratoxin A
22467-31-8
|
US $748.00 / μg | 10g | TargetMol Chemicals Inc. |
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- Rubratoxin A
22467-31-8
- US $748.00 / μg
- TargetMol Chemicals Inc.
