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2-Aminopyridine

2-Aminopyridine
2-Aminopyridine structure
CAS No.
504-29-0
Chemical Name:
2-Aminopyridine
Synonyms
2APY;NSC 431;AKOS 91158;AURORA KA-680;2-Pyridylamin;A-PYRIDYLAMINE;2-PYRIDYLAMINE;2-PYRIDINAMINE;-Aminopyridine;ɑ-Pyridylamine
CBNumber:
CB8152736
Molecular Formula:
C5H6N2
Formula Weight:
94.11
MOL File:
504-29-0.mol

2-Aminopyridine Properties

Melting point:
59 °C
Boiling point:
204-210 °C(lit.)
Density 
1.0308 (estimate)
vapor pressure 
5 hPa (125 °C)
refractive index 
1.5560 (estimate)
Flash point:
198 °F
storage temp. 
Refrigerator, Under Inert Atmosphere
solubility 
890g/l
form 
Crystalline Powder, Crystals or Flakes
pka
6.82(at 20℃)
color 
Cream to light yellow-beige
Odor
Characteristic odour
Water Solubility 
Slightly soluble. 1-5 g/100 mL at 19 ºC
Sensitive 
Hygroscopic
Merck 
14,473
BRN 
105785
Exposure limits
NIOSH REL: TWA 0.5 ppm (2 mg/m3), IDLH 5 ppm; OSHA PEL: 0.5 ppm; ACGIH TLV: TWA 0.5 ppm.
CAS DataBase Reference
504-29-0(CAS DataBase Reference)
EWG's Food Scores
1
FDA UNII
WSX981HEWU
NIST Chemistry Reference
2-Pyridinamine(504-29-0)
EPA Substance Registry System
2-Aminopyridine (504-29-0)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H320-H370-H301+H311-H315-H319-H335-H301-H312-H331-H401-H411
Precautionary statements  P280-P302+P352+P312-P305+P351+P338-P261-P301+P310-P312-P273-P280h-P309-P310-P260-P264-P270-P301+P310+P330-P302+P352+P312+P361+P364-P305+P351+P338+P337+P313-P307+P311-P405-P501
Hazard Codes  T,Xi
Risk Statements  21-25-36/37/38-23/24/25
Safety Statements  26-36/37/39-45-38-28B
RIDADR  UN 2671 6.1/PG 2
WGK Germany  3
RTECS  US1575000
8-21
Autoignition Temperature >630 °C
Hazard Note  Toxic/Irritant
TSCA  Yes
HazardClass  6.1
PackingGroup  II
HS Code  29333999
Toxicity LD50 orally in Rabbit: 200 mg/kg

2-Aminopyridine price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 09340 2-Aminopyridine purum, ≥98.0% (NT) 504-29-0 50g $26.5 2019-12-02 Buy
Sigma-Aldrich 09340 2-Aminopyridine purum, ≥98.0% (NT) 504-29-0 250g $62.3 2019-12-02 Buy
TCI Chemical A0411 2-Aminopyridine >99.0%(GC)(T) 504-29-0 25g $14 2020-06-24 Buy
TCI Chemical A0411 2-Aminopyridine >99.0%(GC)(T) 504-29-0 100g $24 2020-06-24 Buy
Alfa Aesar A12374 2-Aminopyridine, 99% 504-29-0 25g $24.3 2020-06-24 Buy

2-Aminopyridine Chemical Properties,Uses,Production

Chemical Properties

cream to light yellow-beige crystalline powder,

Chemical Properties

2-Aminopyridine is a flammable, colorless crystalline solid, or white leaflets or powder, or colorless liquid with a characteristic odor

Physical properties

Colorless to yellow crystals, leaflets, flakes, or powder with a characteristic odor. May darken after prolonged storage.

Uses

Used to label neutral and acidic glycans for fluorescent and UV detection in HPLC.1 2-AP has also been used to derivatize sialyloligosaccharides for detection in FAB-MS.2

Uses

Compound has been shown to reversibly block voltage-dependent potassium channels, and is also a common impurity from the synthesis of compounds found in hair dyes

Uses

The main use of 2-aminopyridine is in manufacturing pharmaceuticals such as antihistamines.

General Description

White powder or crystals or light brown solid.

Air & Water Reactions

Decomposes in air. Soluble in water.

Reactivity Profile

2-Aminopyridine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides. Reacts with oxidizing agents .

Hazard

Toxic.

Fire Hazard

2-Aminopyridine is combustible.

Safety Profile

Poison by ingestion, inhalation, subcutaneous, intravenous, and intraperitoneal routes. Toxic effects resemble strychnine poisoning. Human systemic effects by inhalation: somnolence, convulsions, and antipsychotic effects. Human central nervous system effects by inhalation. When heated to decomposition it emits highly toxic fumes of NOx,.

Potential Exposure

2-Aminopyridine is used in the manufacture of pharmaceuticals; especially antihistamines.

Environmental Fate

Soil. When radio-labeled 4-aminopyridine was incubated in moist soils (50%) under aerobic conditions at 30 °C, the amount of 14CO2 released from an acidic loam (pH 4.1) and an alkaline, loamy sand (pH 7.8) was 0.4 and 50%, respectively (Starr and Cunningham, 1975).
Chemical/Physical. Releases toxic nitrogen oxides when heated to decomposition (Sax and Lewis, 1987).

Shipping

UN2671 Aminopyridines, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Purification Methods

It crystallises from *benzene/pet ether (b 40-60o) or CHCl3 /pet ether. [Beilstein 22/8 V 280.]

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides

Waste Disposal

Incineration with nitrogen oxides removal from effluent gas.

2-Aminopyridine Preparation Products And Raw materials

Raw materials

Preparation Products


2-Aminopyridine Suppliers

Global( 431)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Frapp's ChemicalNFTZ Co., Ltd.
+86 (576) 8169-6106
+86 (576) 8169-6105 sales@frappschem.com China 886 50
Capot Chemical Co.,Ltd.
+86(0)13336195806 +86-571-85586718
+86-571-85864795 sales@capotchem.com China 19929 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21837 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22625 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555
+86-021-57951555 jack.li@time-chemicals.com CHINA 1365 55
PI & PI BIOTECH INC.
18371201331
020-81716319 Sales@pipitech.com CHINA 3048 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30043 58
Hebei Ruishun Trade Co.,LTD
17052563120
Mike@rsbiology.com CHINA 301 58
Win-Win Chemical CO., Limited
0086-577-64498589
0086-577-56994596 sales@win-winchemical.com CHINA 999 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23977 58

View Lastest Price from 2-Aminopyridine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-12-31 2-Aminopyridine
504-29-0
US $0.00-0.00 / KG 1g 99% 2000tons Shaanxi Dideu Medichem Co. Ltd
2018-09-05 2-Aminopyridine
504-29-0
US $10.00 / KG 1KG 99.9% 100Ton/month Hebei Ruishun Trade Co.,Ltd
2018-07-24 2-aminopyridine
504-29-0
US $100.00-90.00 / KG 1KG 99% Customized career henan chemical co

2-Aminopyridine Spectrum


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