Acrichin dihydrochloride
- CAS No.
- 69-44-3
- Chemical Name:
- Acrichin dihydrochloride
- Synonyms
- AMODIAQUINE HCL;camoquinhydrochloride;Amodiaquine HCL USP31;AMODIAQUIN HYDROCHLORIDE;Acrichin dihydrochloride;Amodiquine hydrochloride;AMODIAQUINE HYDROCHLORIDE;AMODIAQUIN DIHYDROCHLORIDE;AMODIAQUINE DIHYDROCHLORIDE;BULK DRUG : AMODIAQUINE HYDROCHLORIDE (DMF GRADE)
- CBNumber:
- CB8156037
- Molecular Formula:
- C20H23Cl2N3O
- Molecular Weight:
- 392.32
- MDL Number:
- MFCD00078857
- MOL File:
- 69-44-3.mol
| storage temp. | Sealed in dry,Room Temperature |
|---|---|
| solubility | DMSO: 125 mg/mL (291.52 mM) |
| FDA UNII | HOE64181MP |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| WGK Germany | 3 |
Acrichin dihydrochloride price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C429303 | 4-((7-Chloroquinolin-4-yl)amino)-2-((diethylamino)methyl)phenolDihydrochloride | 69-44-3 | 10mg | $45 | 2021-12-16 | Buy |
| ApexBio Technology | C7157 | Amodiaquine hydrochloride | 69-44-3 | 100mg | $50 | 2021-12-16 | Buy |
| ChemScene | CS-0013341 | Amodiaquine(dihydrochloride) ≥98.0% | 69-44-3 | 100mg | $50 | 2021-12-16 | Buy |
| Matrix Scientific | 099311 | 4-((7-Chloroquinolin-4-yl)amino)-2-((diethylamino)-methyl)phenol dihydrochloride 95+% | 69-44-3 | 10g | $10 | 2021-12-16 | Buy |
| ApexBio Technology | C7157 | Amodiaquine hydrochloride | 69-44-3 | 200mg | $80 | 2021-12-16 | Buy |
Acrichin dihydrochloride Chemical Properties,Uses,Production
Chemical Properties
Yellow crystalline solid; odorless; bitter. Soluble in water; sparingly soluble in alcohol; very slightly soluble in benzene, chloroform, and ether.
Originator
Camoquin HCl,Parke Davis,US,1950
Uses
Medicine (antimalarial).
Manufacturing Process
72.8 g (0.5 mol) of p-aminophenol hydrochloride is dissolved in 500 cc of
water and added to 99 g (0.5 mol) of 4,7-dichloroquinoline. After a few
minutes of warming in a steam bath, 4-(4'-hydroxyanilino)-7-chloroquinoline
hydrochloride, of sufficient purity for use in further experiments, precipitates
as a yellow crystalline solid. Recrystallized from methanol, the MP is over
300°C.
A mixture consisting of 13.5 g of 4-(4'-hydroxyanilino)-7-chloroquinoline
hydrochloride dissolved in absolute ethanol is treated with a solution of 4.38 g of diethylamine and 1.8 g of paraformaldehyde in 20 cc of absolute ethanol.
The reaction mixture is heated under reflux for 16 hours, evaporated to onehalf
volume and the warm solution treated with an excess of hydrogen
chloride dissolved in absolute ethanol. Acetone is added to the warm solution
until it becomes turbid and then the solution is cooled. The crude
dihydrochloride which separates is collected and purified by recrystallization
from methanol; MP 240-242°C.
By using an equivalent amount of 4-(4'-hydroxyanilino)-7-bromoquinoline in
the above procedure, 4-(3'-diethylaminomethyl-4'-hydroxyanilino)-7-
bromoquinoline dihydrochloride is obtained; MP (base) 206-208°C dec.
brand name
Camoquin (Parke-Davis).
Therapeutic Function
Antimalarial
Acrichin dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| .GZ HONESTCHEM CO.,LTD | +86-15013270415 | honestchemical@foxmail.com | China | 247 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| zhangjiagang vinsce bio-pharm. limited. | 86-512-58389969 | sales1@swellxin.com | CHINA | 111 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
View Lastest Price from Acrichin dihydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-09-07 | Acrichin dihydrochloride
69-44-3
|
US $30.00 / kg | 1kg | 99% | 1000t/year | Anhui Ruihan Technology Co., Ltd | |
 |
2022-05-17 | Acrichin dihydrochloride
69-44-3
|
US $1.10 / g | 1g | 99.9% Min | 100 Tons | Dideu Industries Group Limited | |
 |
2021-12-10 | Acrichin dihydrochloride
69-44-3
|
US $1.00 / Kg | 1KG | 99.99% | 500 Metric Ton/Day | Handan Tongyi New Material Technology Co., Ltd |
-
- Acrichin dihydrochloride
69-44-3
- US $30.00 / kg
- 99%
- Anhui Ruihan Technology Co., Ltd
-
- Acrichin dihydrochloride
69-44-3
- US $1.10 / g
- 99.9% Min
- Dideu Industries Group Limited
-
- Acrichin dihydrochloride
69-44-3
- US $1.00 / Kg
- 99.99%
- Handan Tongyi New Material Technology Co., Ltd
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