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Bethanechol

Bethanechol
Bethanechol structure
CAS No.
590-63-6
Chemical Name:
Bethanechol
Synonyms
duvoid;Mictone;Uro-Carb;NSC 30783;Mechotane;Mecothane;Betanechol;mechothane;myocholine;urecholine
CBNumber:
CB8156880
Molecular Formula:
C7H17ClN2O2
Formula Weight:
196.68
MOL File:
590-63-6.mol

Bethanechol Properties

Melting point:
187-190°C
storage temp. 
2-8°C
solubility 
H2O: 1.7 g/mL stable for several days at 4°C.
form 
crystalline
color 
white
Merck 
14,1185
CAS DataBase Reference
590-63-6(CAS DataBase Reference)
EPA Substance Registry System
1-Propanaminium, 2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-, chloride (590-63-6)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330-P264-P270-P301+P312a-P330-P501a
Hazard Codes  Xn
Risk Statements  22
Safety Statements  36
WGK Germany  3
RTECS  BR5425000
TSCA  Yes
HS Code  2924190002

Bethanechol price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C5259 Carbamyl-β-methylcholine chloride ≥99% (TLC), crystalline 590-63-6 5g $158 2019-12-02 Buy
Sigma-Aldrich 1071009 Bethanechol chloride United States Pharmacopeia (USP) Reference Standard 590-63-6 200mg $352.8 2019-12-02 Buy
TCI Chemical B4828 Bethanechol Chloride >98.0%(T) 590-63-6 5g $84 2019-12-02 Buy
TCI Chemical B4828 Bethanechol Chloride >98.0%(T) 590-63-6 25g $289 2019-12-02 Buy
Alfa Aesar J65919 Bethanechol chloride, 98% 590-63-6 5g $104 2019-12-02 Buy

Bethanechol Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

cholinergic

Uses

A selective muscarinic receptor stimulant, used to treat cerebral palsy.

Definition

ChEBI: The chloride salt of bethanechol. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention.

brand name

Duvoid (WellSpring); Myotonachol (Glenwood); Urecholine (Odyssey).

General Description

Bethanechol, β-methylcholinechloride carbamate, (2-hydroxypropyl)trimethylammoniumchloride carbamate, carbamylmethylcholinechloride (Urecholine), is nonspecific in its action on muscarinicreceptor subtypes but appears to be more effective ateliciting pharmacological action of M3 receptors. It haspharmacological properties similar to those of methacholine.Both are esters of β-methylcholine and have feeblenicotinic activity. Bethanechol is inactivated more slowlyby AChE in vivo than is methacholine. It is a carbamyl esterand is expected to have stability in aqueous solutions similarto that of carbachol.

Hazard

Headache, flushing, gastrointestinal distress, diarrhea, hypotension, excessive salivation, sweating, hypersensitivity.

Clinical Use

The main use of bethanechol chloride is in the relief ofurinary retention and abdominal distention after surgery.The drug is used orally and by subcutaneous injection. Itmust never be administered by intramuscular or intravenousinjection because of the danger from cholinergic overstimulationand loss of selective action. Proper administration ofthe drug is associated with low toxicity and no serious sideeffects. Bethanechol chloride should be used with caution inasthmatic patients; when used for glaucoma, it producesfrontal headaches from the constriction of the sphinctermuscle in the eye and from ciliary muscle spasms. Its durationof action is 1 hour.

Veterinary Drugs and Treatments

In veterinary medicine, bethanechol is used primarily to stimulate bladder contractions in small animals. It also can be used as an esophageal or general GI stimulant, although metoclopramide and/ or neostigmine have largely supplanted it for these uses.

Bethanechol Preparation Products And Raw materials

Raw materials

Preparation Products


Bethanechol Suppliers

Global( 212)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21687 58
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497 sales01@cooperate-pharm.com CHINA 1817 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22633 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sale@mainchem.com CHINA 32447 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3015 60
Hubei XinRunde Chemical Co., Ltd.
+8615102730682
02783214688 bruce@xrdchem.cn CHINA 570 55
Anhui Royal Chemical Co., Ltd.
+86-025-86736275
dana.jiang@royal-chem.com CHINA 511 55
Hebei Chisure Biotechnology Co., Ltd.
+8613292890173
0311 66567340 luna@speedgainpharma.com CHINA 1014 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29995 58

View Lastest Price from Bethanechol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-24 Bethanechol
590-63-6
US $2.00 / kg 1kg 99% 100kg career henan chemical co
2019-04-28 Bethanechol
590-63-6
US $10.00 / ASSAYS 1ASSAYS 99% 500tons/month Hebei Chisure Biotechnology Co., Ltd.

Bethanechol Spectrum


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