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Sertraline hydrochloride

Description References
Sertraline hydrochloride
Sertraline hydrochloride structure
CAS No.
79559-97-0
Chemical Name:
Sertraline hydrochloride
Synonyms
CP-51974-1;SETRALINE HCL;CP-51974-1 HCl;(1s-cis)-lorid;Lustral:Zoloft;SERTRALINE MANDELATE;Sertraline hydrochlo;SERTRALINE HCL FORM I;SERTRALINE HCL FORM II;Sertaline hydrochloride
CBNumber:
CB8157645
Molecular Formula:
C17H18Cl3N
Formula Weight:
342.69
MOL File:
79559-97-0.mol

Sertraline hydrochloride Properties

Melting point:
246-249°C
alpha 
D23 +37.9° (c = 2 in methanol)
Density 
1.37
Flash point:
9℃
storage temp. 
Desiccate at RT
solubility 
DMSO: ~26 mg/mL
form 
solid
pka
pKa (water): 9.48 ± 0.04; pKa (methanol:water, 40:60 v/v): 8.6; pKa (ethanol:water, 1:1 v/v): 8.5(at 25℃)
color 
white
Merck 
14,8467
Stability:
Store in Freezer
CAS DataBase Reference
79559-97-0(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi,T,F
Risk Statements  36/37/38-39/23/24/25-23/24/25-11
Safety Statements  22-24/25-36-26-45-36/37-16-7
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  3
RTECS  QJ0352070
HazardClass  IRRITANT
HS Code  29214990
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P311 Call a POISON CENTER or doctor/physician.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P501 Dispose of contents/container to..…

Sertraline hydrochloride price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S-021 Sertraline hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material 79559-97-0 021-1ml $37.1 2018-11-13 Buy
Sigma-Aldrich 1612539 Sertraline hydrochloride United States Pharmacopeia (USP) Reference Standard 79559-97-0 100mg $899.15 2018-11-13 Buy
TCI Chemical S0507 Sertraline Hydrochloride >98.0%(HPLC)(T) 79559-97-0 1g $56 2018-11-22 Buy
TCI Chemical S0507 Sertraline Hydrochloride >98.0%(HPLC)(T) 79559-97-0 5g $192 2018-11-22 Buy
Cayman Chemical 14839 Sertraline (hydrochloride) ≥95% 79559-97-0 5mg $40 2018-11-13 Buy

Sertraline hydrochloride Chemical Properties,Uses,Production

Description

Sertraline is the hydrochloride form of sertraliine. Sertraline belongs to the selective serotonin reuptake inhibitor (SSRI) class antidepressant drug. Sertraline is indicated for the treatment of major depressive disorder in adults as well as obsessive-compulsive disorder, post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder and social anxiety disorder occurring in both adults and children. Its exact mechanism of action is still not fully understand. But it is indicated that this drug can selectively inhibit the reuptake of serotonin at the presynaptic membrane, increasing serotonin levels in the synapses and enhancing serotonergic neurotransmission. This effect seems to be related to the antidepressant effect of sertraliine.

References

https://en.wikipedia.org/wiki/Sertraline
https://www.drugbank.ca/drugs/DB01104

Description

Sertraline hydrochloride is a selective serotonin reuptake inhibitor, similar mechanistically to fluoxetine, introduced initially for the maintenance and long-term treatment of depression. It is reportedly non-sedating and compared to fluoxetine has a shorter duration of action and lack of CNS activating effects such as nervousness and anxiety. Sertraline hydrochloride is currently undergoing investigation for the treatment of obesity and obsessive-compulsive disorders.

Chemical Properties

White or almost white, crystalline powder.

Originator

Pfizer (USA)

Uses

A selective serotonin reuptake inhibitor. Used as an antidepressant

Uses

antibacterial

Uses

A selective ST inhibitor

Definition

ChEBI: A hydrochloride resulting from the reaction of equimolar amounts of sertraline and hydrogen chloride. A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as an antidepressant for the treatment of depression, obsessive-compulsive diso der, panic disorder and post-traumatic stress disorder.

brand name

Zoloft (Pfizer);Lustral.

Biological Activity

Potent, orally active selective serotonin re-uptake inhibitor (SSRI) used clinically to treat depression.

Sertraline hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products


Sertraline hydrochloride Suppliers

Global( 264)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21930 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32457 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 E-mail:sales03@shyrchem.com
+86-21-34979012 sales03@shyrchem.com CHINA 661 60
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114
sales@amoychem.com CHINA 6374 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 20516 58
Shaanxi Yikanglong Biotechnology Co., Ltd.
17791478691
yklbiotech@163.com CHINA 297 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20094 58
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8409 58

View Lastest Price from Sertraline hydrochloride manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-22 Sertraline hydrochloride
79559-97-0
US $7.00 / kg 1kg 99% 100KG career henan chemical co

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