ChemicalBook >> CAS DataBase List >>PROSTACYCLIN SODIUM SALT
PROSTACYCLIN SODIUM SALT
- CAS No.
- 61849-14-7
- Chemical Name:
- PROSTACYCLIN SODIUM SALT
- Synonyms
- PGI2;Flolan;PG12-NA;PGI2-NA;PGI2 sodium;Sodium PGI2;EPOPROSTENOL;Eprostol sodium;PROSTAGLANDIN I2;Prostaglandin 12
- CBNumber:
- CB8167138
- Molecular Formula:
- C20H33NaO5
- Molecular Weight:
- 376.47
- MDL Number:
- MFCD00135629
- MOL File:
- 61849-14-7.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
| Melting point | 168-170 °C |
|---|---|
| RTECS | UK8008700 |
| storage temp. | -20°C |
| solubility | H2O: 1 mg/mL Hydrolyzes to 6-ketoprostaglandin F1α in aqueous solution. |
| form | powder |
| color | white |
| Water Solubility | Soluble to 100 mM in water |
| Sensitive | Moisture Sensitive |
| Merck | 13,7967 |
| BRN | 6472195 |
| Stability | Light Sensitive, Temperature Sensitive |
| CAS DataBase Reference | 61849-14-7(CAS DataBase Reference) |
| FDA UNII | 4K04IQ1OF4 |
| ATC code | B01AC09 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H302-H312-H332 |
| Precautionary statements | P261-P280-P301+P312+P330-P280h-P301+P312a-P304+P340-P321-P501a |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22 |
| Safety Statements | 22-26-36 |
| WGK Germany | 3 |
| F | 3-10 |
| HS Code | 29329900 |
PROSTACYCLIN SODIUM SALT price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1237600 | Epoprostenol sodium United States Pharmacopeia (USP) Reference Standard | 61849-14-7 | 100mg | $3490 | 2024-03-01 | Buy |
| Alfa Aesar | J67115 | Prostaglandin I2 sodium salt, 99% | 61849-14-7 | 1mg | $159 | 2023-06-20 | Buy |
| Cayman Chemical | 18220 | Prostaglandin I2 (sodium salt) ≥98% | 61849-14-7 | 1mg | $73 | 2024-03-01 | Buy |
| Cayman Chemical | 18220 | Prostaglandin I2 (sodium salt) ≥98% | 61849-14-7 | 5mg | $324 | 2024-03-01 | Buy |
| Sigma-Aldrich | P6188 | Prostaglandin I2 sodium salt ≥96% (HPLC), synthetic, powder | 61849-14-7 | 1mg | $435 | 2024-03-01 | Buy |
PROSTACYCLIN SODIUM SALT Chemical Properties,Uses,Production
Description
Epoprostenol is a naturally occurring prostaglandin indicated for the preservation of platelet function during cardiopulmonary bypass, prevention of platelet aggregation during charcoal hemoperfusion of patients in hepatic failure, and as an alternative to heparin during renal dialysis.
Chemical Properties
Epoprostenol is white crystalline powder
Originator
Burroughs Wellcome (United Kingdom)
Uses
Prostaglandin I2 sodium salt has been used:
- in the preparation of stock solution for platelet washing procedure
- as supplement in platelet-rich-plasma, for platelet preparation
- to prevent platelet activation
Uses
Epoprostenol is an Eicosanoid which prevents the formation of platelet plugs and is an effective vasodilator.
Manufacturing Process
Preparation of prostacyclin:
Pig aortas were stripped of adventitia, snap frozen in liquid nitrogen, crushed
into a fine powder, resuspended in 0.05 M Tris buffer (pH 7.5) (1:4, w:v) andhomogenised at high speed in a Polytron (KIMENATIC, LUCERNE,
SWITZERLAND) homogenizer. The homogenate was centrifuged for 15 min
and the resulting supernatant centrifuged again for 5 min. The pellet was
discarded, while the pellet obtained after centrifugation of the supernatant
was resuspended in deionized water and lyophilized. An average yield of 150
mg of aortic microsomal powder (51% protein) per 100 g of aortic tissue was
obtained.
brand name
Flolan (GlaxoSmithKline);CYCLO-PROSTIN.
Therapeutic Function
Platelet aggregation inhibitor, Antimetastatic
Biological Activity
Epoprostenol is a potent agonist at IP prostanoid receptors. Inhibits platelet aggregation and induces vasodilation.
Biochem/physiol Actions
Prostacyclin therapy improves hemodynamics in pulmonary arterial hypertension.
storage
Desiccate at -80°C
PROSTACYCLIN SODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 158)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9320 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29220 | 58 |
View Lastest Price from PROSTACYCLIN SODIUM SALT manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-06-04 | PROSTACYCLIN SODIUM SALT USP/EP/BP
61849-14-7
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2019-07-14 | PROSTACYCLIN SODIUM SALT
61849-14-7
|
US $1.00 / KG | 1KG | 99% | 25kg | Career Henan Chemical Co |
-
- PROSTACYCLIN SODIUM SALT USP/EP/BP
61849-14-7
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- PROSTACYCLIN SODIUM SALT
61849-14-7
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
61849-14-7(PROSTACYCLIN SODIUM SALT)Related Search:
Sodium (5Z,13E,15S)-6,9a-epoxy-11a,15-dihydroxyprosta-5,13-dien-1-oate
cGMP Epoprostenol (sodium salt)
(5Z,13E,8R,9S,11R,12R,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oicacidsodiumsalt
Prostacyclin sodium salt Epoprostenol sodium
PGI2Na (Prostaglandin I2Na, Prostacyclin)
Prostaglandin I?, Sodium Salt
EPOPROSTENOL
EPOPROSTENOL SODIUM
EPOPROSTENOL SODIUM SALT
(5-Z)-9-DEOXY-6,9ALPHA-EPOXY-PGF1ALPHA, SODIUM SALT
[5Z,9ALPHA,11ALPHA,13E,15S]-6,9-EPOXY-11,15-DIHYDROXYPROSTA-5,13-DIEN-1-OIC ACID SODIUM SALT
6,9ALPHA-EPOXY-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID, SODIUM SALT
PROSTACYCLINE SODIUM SALT
PROSTACYCLIN SODIUM SALT
PROSTAGLANDINS I2 SODIUM SALT
PROSTAGLANDIN I2
PROSTAGLANDIN I2 NA
PROSTAGLANDIN I2 SODIUM SALT
PG12-NA
PGI2
PGI2-NA
PGI2, SODIUM SALT
(5z,9α,11α,13e,15s)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt
Flolan
PGI2 sodium
Prosta-5,13-dien-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, monosodium salt, (5Z,9α,11α,13E,15S)-
Prostacyclin sodium
Sodium PGI2
Sodium prostacyclin
Epoprostenol sodium salt, PGI2-Na, Prostacyclin sodium salt, (5Z,9α,11α,13E,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt
sodium (5Z,13E,15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dien-1-oate
PROSTAGLANDIN I2 SODIUM
Prostaglandin 12
(5-Z)-9-DEOXY-6,9ALPHA-EPOXY-PGF1ALPHA, SODIUM SALT, 98%, STABILIZED
(5-Z)-9-Deoxy-6,9alpha-epoxy-PGF1alpha, sodium salt, stabilized
(5Z)-5-[(3aR,4R,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]pentanoate
Prostaglandin I, Sodium Salt - CAS 61849-14-7 - Calbiochem
PROSTACYCLIN SODIUM SALT USP/EP/BP
Epoprostenol ELISA Kit
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Epoprostenol sodium
TIANFU CHEM--PROSTACYCLIN SODIUM SALT
Epoprostenol Sodium (COLD SHIPMENT REQUIRED) (1237600)
Eprostol sodium
61849-14-7
C20H32NaO5
C20H31O5Na
C20H31NaO5
Fatty Acids
Lipids
Prostaglandins
Biochemicals and Reagents
BioChemical
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