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5-METHOXY-2-METHYLINDOLE

CAS No.
1076-74-0
Chemical Name:
5-METHOXY-2-METHYLINDOLE
Synonyms
NSC 63817;AKOS JY2082626;5-Methoxy-2-methyindole;2-Methyl-5-Methoxyindole;5-METHOXY-2-METHYLINDOLE;Indole, 5-methoxy-2-methyl-;5-Methoxy-2-methylindole>5-Methoxy-2-methylindole 99%;1H-Indole, 5-methoxy-2-methyl-;5-Methoxy-2-methylindole, 99+%
CBNumber:
CB8174569
Molecular Formula:
C10H11NO
Molecular Weight:
161.2
MDL Number:
MFCD00005620
MOL File:
1076-74-0.mol
MSDS File:
SDS
Last updated:2023-05-25 10:25:47

5-METHOXY-2-METHYLINDOLE Properties

Melting point 86-88 °C (lit.)
Boiling point 145 °C / 1.5mmHg
Density 1.0840 (rough estimate)
refractive index 1.5200 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Soluble in methanol (very faint turbidity.)
pka 17.28±0.30(Predicted)
form Crystalline Powder or Crystals
color White to light beige
InChIKey VSWGLJOQFUMFOQ-UHFFFAOYSA-N
CAS DataBase Reference 1076-74-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  37/39-26
WGK Germany  3
HazardClass  IRRITANT
HS Code  29339900
NFPA 704
1
2 0

5-METHOXY-2-METHYLINDOLE price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M15451 5-Methoxy-2-methylindole 99% 1076-74-0 1g $52.4 2024-03-01 Buy
Sigma-Aldrich M15451 5-Methoxy-2-methylindole 99% 1076-74-0 5g $174 2024-03-01 Buy
TCI Chemical M0730 5-Methoxy-2-methylindole >99.0%(GC) 1076-74-0 1g $147 2024-03-01 Buy
TCI Chemical M0730 5-Methoxy-2-methylindole >99.0%(GC) 1076-74-0 5g $584 2024-03-01 Buy
Alfa Aesar B21348 5-Methoxy-2-methylindole, 99+% 1076-74-0 1g $31.65 2024-03-01 Buy
Product number Packaging Price Buy
M15451 1g $52.4 Buy
M15451 5g $174 Buy
M0730 1g $147 Buy
M0730 5g $584 Buy
B21348 1g $31.65 Buy

5-METHOXY-2-METHYLINDOLE Chemical Properties,Uses,Production

Description

5-methoxy-2-methylindole is a useful organic raw material. It can be used as the reactant in the preparation of indolylquinoxalines by condensation reactions, in preparation of alkylindoles via Ir-catalyzed reductive alkylation, in arylation reactions in the presence of a palladium acetate catalyst, in enantioselective Friedel-Crafts alkylation, as well as in stereo selective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation. It is also employed in inhibiting the chlorinating activity of myeloperoxidase (MPO) and in the metabolic synthesis of acrylacetic acid anti-inflammatory synthesis.

Chemical Properties

white to light beige crystalline powder or

Uses

It is employed as a reactant in preparation of indolylquinoxalines by condensation reactions, reactant in preparation of alkylindoles via Ir-catalyzed reductive alkylation, reactant in arylation reactions using a palladium acetate catalyst, reactant in enantioselective Friedel-Crafts alkylation and reactant in stereoselective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation. As an indole derivative shown to be an effective inhibitor of the chlorinating activity of myeloperoxidase (MPO). Used in the metabolic synthesis of arylacetic acid anti-inflammatory synthesis.

Uses

reactant in preparation of indolylquinoxalines by condensation reactions1reactant in preparation of alkylindoles via Ir-catalyzed reductive alkylation2reactant in arylation reactions using a palladium acetate catalyst3reactant in enantioselective Friedel-Crafts alkylation4reactant in stereoselective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation5

Uses

An indole derivative shown to be an effective inhibitor of the chlorinating activity of myeloperoxidase (MPO). Used in the metabolic synthesis of arylacetic acid antiinflammatory synthesis.

Definition

ChEBI: 5-Methoxy-2-methyl-1H-indole is a member of indoles.

References

https://www.alfa.com/en/catalog/B21348/
http://www.sigmaaldrich.com/catalog/product/aldrich/m15451?lang=en&region=US
https://pubchem.ncbi.nlm.nih.gov/compound/5-Methoxy-2-methylindole#section=2D-Structure

104-94-9
116-09-6
1076-74-0
Synthesis of 5-METHOXY-2-METHYLINDOLE from p-Anisidine and Hydroxyacetone
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View Lastest Price from 5-METHOXY-2-METHYLINDOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
 5-Methoxy-2-methylindole pictures 2022-09-20 5-Methoxy-2-methylindole
1076-74-0
US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
5-METHOXY-2-METHYLINDOLE pictures 2019-12-23 5-METHOXY-2-METHYLINDOLE
1076-74-0
US $0.00 / g 1g 95%min 20kg/month Nanjing jinheyou Trading Co., Ltd.
5-METHOXY-2-METHYLINDOLE pictures 2019-07-06 5-METHOXY-2-METHYLINDOLE
1076-74-0
US $1.00 / kg 1kg 98% 100KG Career Henan Chemical Co
5-Methoxy-2-methylindole, 99+% 5-METHOXY-2-METHYLINDOLE AKOS JY2082626 5-Methoxy-2-methyindole Indole, 5-methoxy-2-methyl- 5-Methoxy-2-Methylindole, 99+% 25GR 5-Methoxy-2-Methylindole, 99+% 5GR 2-Methyl-5-Methoxyindole NSC 63817 5-Methoxy-2-methylindole 99% 1H-Indole, 5-methoxy-2-methyl- 5-Methoxy-2-methylindole> 5-Methoxy-2-methylindole, 99%, for synthesis 1076-74-0 Heterocyclic Building Blocks Building Blocks Simple Indoles Indoles Building Blocks C10 Chemical Synthesis Heterocyclic Building Blocks Aromatics Heterocycles Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Indoles Simple Indoles Building Blocks Heterocyclic Building Blocks Indole Indoles and derivatives