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ChemicalBook >> CAS DataBase List >>1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol

1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol

1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol Structure
1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol structure
CAS No.
685514-01-6
Chemical Name:
1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol
Synonyms
1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol;1-triisopropylsilylpyrrolo[2,3-b]pyridin-5-ol;1-tri(propan-2-yl)silylpyrrolo[2,3-b]pyridin-5-ol;1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridin-5-ol;1-[tris(propan-2-yl)silyl]-1H-pyrrolo[2,3-b]pyridin-5-ol;1-[Tris(1-methylethyl)silyl]-1H-pyrrolo[2,3-b]pyridin-5-ol;1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]-;1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-sulfonic acid
CBNumber:
CB81871753
Molecular Formula:
C16H26N2OSi
Molecular Weight:
290.48
MDL Number:
MFCD11616408
MOL File:
685514-01-6.mol
MSDS File:
SDS
Last updated:2024-03-29 15:21:39
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1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol Properties

Boiling point 341.6±35.0 °C(Predicted)
Density 1.03±0.1 g/cm3(Predicted)
pka 8.50±0.40(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-B1523 1H-Pyrrolo[2,3-b]pyridin-5-ol,1-[tris(1-methylethyl)silyl]- 685514-01-6 250mg $56 2021-12-16 Buy
ChemScene CS-B1523 1H-Pyrrolo[2,3-b]pyridin-5-ol,1-[tris(1-methylethyl)silyl]- 685514-01-6 1g $112 2021-12-16 Buy
American Custom Chemicals Corporation ORS0004629 1-[TRIS-(1-METHYLETHYL)SILYL]-1H-PYRROLO[2,3-B]PYRIDIN-5-OL 95.00% 685514-01-6 5MG $498.83 2021-12-16 Buy
ChemScene CS-B1523 1H-Pyrrolo[2,3-b]pyridin-5-ol,1-[tris(1-methylethyl)silyl]- 685514-01-6 5g $336 2021-12-16 Buy
Matrix Scientific 179557 1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridin-5-ol 685514-01-6 1g $826 2021-12-16 Buy
Product number Packaging Price Buy
CS-B1523 250mg $56 Buy
CS-B1523 1g $112 Buy
ORS0004629 5MG $498.83 Buy
CS-B1523 5g $336 Buy
179557 1g $826 Buy

1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol Chemical Properties,Uses,Production

Synthesis

Add 10.8g (34mmol) of (1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)boronic acid and 120mL of tetrahydrofuran to a round bottom flask equipped with a magnetic stirrer, an inert gas source and a separating funnel, and stir to dissolve; Add 34mL of 1mol/L sodium hydroxide solution and 4.60g (40.6mmol) of 30% hydrogen peroxide dropwise at 0°C. After the addition, React at 0°C for 1 hour and detect the reaction by TLC. Add 4.8g (20.24mmol) of sodium thiosulfate, adjust to pH=5 with 2mol/L hydrochloric acid, extract with ethyl acetate (2x200mL), combine the organic phases, wash with saturated brine in turn, dry with a sodium sulfate, and reduce Concentrate under pressure. The residue was purified by silica gel column chromatography [eluent: dichloromethane] to obtain 1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol 9.4g, yield 95.0%.
1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]-

1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol Preparation Products And Raw materials

Raw materials

Preparation Products

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid

1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol Suppliers

Global( 44)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Yingrui Biopharma Co., Ltd. 		+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60
Shanghai Yingrui Biopharma Co.,Ltd 		21-33585366 export01@shyrchem.com CHINA 1320 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Labnetwork lnc. 		+86-27-50766799 +8618062016861 contact@labnetwork.com China 19994 58
Hefei TNJ Chemical Industry Co.,Ltd. 		0551-65418684 +8618949823763 sales@tnjchem.com China 25363 58
Yangzhou Qinyuan Pharmatech Co.,ltd 		+86-18752526868 jennysun@yzqyyykj.com China 64 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43348 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD. 021-34666753 13311639313 info@shyrchem.com China 570 55
Supplier Advantage
Shanghai Yingrui Biopharma Co., Ltd. 		60
Shanghai Yingrui Biopharma Co.,Ltd 		58
career henan chemical co 		58
Labnetwork lnc. 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Yangzhou Qinyuan Pharmatech Co.,ltd 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
LEAPCHEM CO., LTD. 		58
Amadis Chemical Company Limited 		58
SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD. 55

View Lastest Price from 1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]- pictures 2022-06-23 1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]-
685514-01-6
 US $0.00 / g 10g 98% 10tons Yangzhou Qinyuan Pharmatech Co.,ltd
1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]- pictures 2020-02-17 1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]-
685514-01-6
 US $1.00 / KG 1KG 99% 200kgs Career Henan Chemical Co
1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]- pictures 2018-03-07 1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]-
685514-01-6
 US $0.00 / KG 0KG 99% 100t Shanghai Yingrui Biopharma Co., Ltd.

685514-01-6(1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol)Related Search:

2-[(1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy]-4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl]methyl]piperazin-1-yl]benzoic acid 1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine ABT-199 Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 3-nitro-4-((tetrahydro-2H-pyran-4-yl)MethylaMino)benzenesulfonaMide
4'-chloro-5,5-diMethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-carbaldehyde 1H-PYRROLO[2,3-B]PYRIDIN-5-OL

1of2

1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]- 1-[Tris(1-methylethyl)silyl]-1H-pyrrolo[2,3-b]pyridin-5-ol 1-triisopropylsilylpyrrolo[2,3-b]pyridin-5-ol 1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-sulfonic acid 1-[tris(propan-2-yl)silyl]-1H-pyrrolo[2,3-b]pyridin-5-ol 1-tri(propan-2-yl)silylpyrrolo[2,3-b]pyridin-5-ol 1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridin-5-ol 1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol 685514-01-6 C16H26N2OSi