DIPEPTIDYLPEPTIDASE IV INHIBITOR I

CAS No.
Chemical Name:
DIPEPTIDYLPEPTIDASE IV INHIBITOR I
Synonyms
DIPEPTIDYLPEPTIDASE IV INHIBITOR I
CBNumber:
CB8187497
Molecular Formula:
C19H32F3N3O6
Molecular Weight:
455.47
MDL Number:
MFCD00270878
MOL File:
Mol file

DIPEPTIDYLPEPTIDASE IV INHIBITOR I price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D3822 Dipeptidyl Peptidase IV Inhibitor I 5MG $241 2023-06-20 Buy
Product number Packaging Price Buy
D3822 5MG $241 Buy

DIPEPTIDYLPEPTIDASE IV INHIBITOR I Chemical Properties,Uses,Production

Biochem/physiol Actions

Dipeptidyl peptidase IV is a key enzyme involved in the regulation of incretin hormone levels in the gastrointestinal tract. Incretin hormones, such as glucagon like peptide (GLP-1) and glucose-dependent insulinotopic hormone (GIP) / gastoric inhibitory peptide, cause the glucose stimulated release of insulin. This allows the endocrine system to preemptively stimulate release insulin in response to ingestion of high sugar foods. Type 2 diabetics demonstrate a greatly reduced incretin induced insulin release response. This response in hyperglycemic conditions is counterbalanced by the rapid rate of degradation of these incretin hormones by dipeptidyl peptidase IV in normal conditions. Inhibition of dipeptidyl peptidase IV results in longer lifetime of the incretin hormones in the GI tract and thus prolonged stimulation of insulin production. Specific dipeptidyl peptidase inhibitors are actively being explored as drug targets for treating type 2 diabetes and several candidates are actively in clinical trial. Dipeptidyl peptidase IV (Diprotin A) inhibits both endo- and exopeptidase activities of Dipeptidyl peptidase IV.

DIPEPTIDYLPEPTIDASE IV INHIBITOR I Preparation Products And Raw materials

Raw materials

Preparation Products

DIPEPTIDYLPEPTIDASE IV INHIBITOR I Suppliers

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DIPEPTIDYLPEPTIDASE IV INHIBITOR I