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Fludarabine

Fludarabine
Fludarabine
CAS No.
21679-14-1
Chemical Name:
Fludarabine
Synonyms
f-ara-a;Fludara;2-F-ARAA;NSC 118218;NSC-312887;NSC-328002;ludarabine;21697-14-1;Fludarbine;NSC 118218H
CBNumber:
CB8188247
Molecular Formula:
C10H12FN5O4
Formula Weight:
285.23
MOL File:
21679-14-1.mol

Fludarabine Properties

Melting point:
265-268°C
alpha 
D25 +17 ±2.5° (c = 0.1 in ethanol)
storage temp. 
2-8°C
solubility 
DMF: 20 mg/mL, clear, faintly yellow
form 
Powder
color 
White to Pale Yellow
Water Solubility 
Soluble in DMF, DMSO, methanol or ethanol. Sparingly soluble in water
Merck 
13,4152
BRN 
1225932
CAS DataBase Reference
21679-14-1(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn
Risk Statements  23/24/25-36/37/38-39/23/24/25-39-22
Safety Statements  26-36/37-45-36
WGK Germany  3
RTECS  AU6207000
10
Hazardous Substances Data 21679-14-1(Hazardous Substances Data)
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:

Fludarabine price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich F2773 2-Fluoroadenine-9-β-D-arabinofuranoside DNA synthesis and methylation inhibitor 21679-14-1 5mg $125 2018-11-13 Buy
Sigma-Aldrich F2773 2-Fluoroadenine-9-β-D-arabinofuranoside DNA synthesis and methylation inhibitor 21679-14-1 10mg $225 2018-11-13 Buy
Alfa Aesar J65562 2-Fluoro-9-beta-D-arabinofuranosyladenine, 98% 21679-14-1 1g $61.2 2018-11-13 Buy
Cayman Chemical 14128 Fludarabine ≥98% 21679-14-1 5mg $25 2018-11-13 Buy
Cayman Chemical 14128 Fludarabine ≥98% 21679-14-1 10mg $43 2018-11-13 Buy

Fludarabine Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Used as an antineoplastic

Uses

A STAT-1 activation inhibitor and a DNA synthesis inhibitor.?

Uses

phosphate as antineoplastic;inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase

Uses

Irreversible muscarinic agonist

Uses

DNA synthesis and methylation inhibitor;A cell permeable agent that interferes with DNA synthesis and repair; also inhibits RNA transcription

Biological Activity

Purine analog that inhibits DNA synthesis. Exhibits antiproliferative activity (IC 50 = 1.54 μ M in RPMI cells) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP and survivin expression. Displays anticancer activity against hematological malignancies in vivo .

Fludarabine Preparation Products And Raw materials

Raw materials

Preparation Products


Fludarabine Suppliers

Global( 305)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3217 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22046 58
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497 sales01@cooperate-pharm.com CHINA 1530 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
+86-571-56059825 fandachem@gmail.com CHINA 2110 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 bruce@xrdchem.cn CHINA 552 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 14293 60
QUALITY CONTROL CHEMICALS INC.
13606120588
orders@qcchemical.com CHINA 8430 58
Shenzhen Nexconn Pharmatechs Ltd
15013857715
admin@nexconn.com CHINA 2515 58

View Lastest Price from Fludarabine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-03-28 Fludarbine
21679-14-1
US $10.00 / KG 10G 99% 10MT Hubei XinRunde Chemical Co., Ltd.
2018-08-15 Fludarabine
21679-14-1
US $1.00 / KG 1KG 99% 1000KG career henan chemical co

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