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A[5']P5[5']A SODIUM SALT

CAS No.
4097-04-5
Chemical Name:
A[5']P5[5']A SODIUM SALT
Synonyms
A(5′)P5(5′)A;A[5']P5[5']A SODIUM SALT;DIADENOSINE PENTAPHOSPHATE SODIUM SALT;Diadenosine pentaphosphate pentasodium;5'-ester with adenosine pentasodium salt;P1,P5-Di(adenosine-5;P1,P5-DI(ADENOSINE-5') PENTAPHOSPHATESOD IUM;Diadenosine pentaphosphate pentasodium salt;P1,P5-DI(ADENOSINE-5') PENTAPHOSPHATE SODIUM SALT;P1,P5-di(adenosine-5')pentaphosphate pentasodium salt 5H2O
CBNumber:
CB8189688
Molecular Formula:
C20H24N10Na5O22P5
Molecular Weight:
1026.28
MDL Number:
MFCD00077718
MOL File:
4097-04-5.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

A[5']P5[5']A SODIUM SALT Properties

storage temp. -20°C
solubility H2O: 50 mg/mL
form powder
color white to white with yellow cast
BRN 4949216

SAFETY

Risk and Safety Statements

WGK Germany  3
10-21

A[5']P5[5']A SODIUM SALT price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D4022 P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt ≥95% (HPLC), powder 4097-04-5 2MG $64.2 2023-06-20 Buy
Sigma-Aldrich D4022 P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt ≥95% (HPLC), powder 4097-04-5 10MG $158 2023-06-20 Buy
Sigma-Aldrich D4022 P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt ≥95% (HPLC), powder 4097-04-5 25MG $310 2023-06-20 Buy
Sigma-Aldrich D4022 P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt ≥95% (HPLC), powder 4097-04-5 50MG $557 2023-06-20 Buy
Usbiological 296060 Diadenosine pentaphosphate pentasodium salt 4097-04-5 2mg $347 2021-12-16 Buy
Product number Packaging Price Buy
D4022 2MG $64.2 Buy
D4022 10MG $158 Buy
D4022 25MG $310 Buy
D4022 50MG $557 Buy
296060 2mg $347 Buy

A[5']P5[5']A SODIUM SALT Chemical Properties,Uses,Production

Uses

P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt has been used as:

  • an adenylate kinase (AK) inhibitor in: sarcoma osteogenic (Saos-2) cells
  • mitochondrial lysates during ATP synthesis
  • tetramethylrhodamine methyl ester (TMRM) based membrane potential assay
  • chromoplasts

General Description

P1,P5-Di(adenosine-5′) pentaphosphate (Ap5A) is a diadenosine polyphosphate, which has a tail-to-tail dimer structure. Ap5A is synthesized in a twostep process involving the formation of adenosine 5′-tetraphosphate (P4A) from the ATP and trimeta-phosphate (P3). In the second step, P4A is converted to Ap5A. The synthesis of Ap5A requires a pH optimum in the range of 7.5 to 8.5 and is modulated by metal ions.

Biochem/physiol Actions

A diadenosine polyphosphate stored in secretory granules of thrombocytes, chromaffin and neuronal cells. After release into the extracellular space, it affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5′-nucleotidase and inhibits adenosine kinase activity in vitro. Ap5A is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. In cardiac muscle, pM to nM concentrations significantly increase the open-probability of ryanodine-receptor (RyR2) gates, with prolonged action due to slow dissociation from the receptor.

A[5']P5[5']A SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

A[5']P5[5']A SODIUM SALT Suppliers

Global( 32)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
BEST-REAGENT 400-1166-196 18981987031 cdhxsj@163.com China 11726 57
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 22519 55
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 18521732826; market@aladdin-e.com China 25015 65
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Codow Chemical Co.,Ltd. 18620099427 amy@howeipharm.com China 17698 55
Chengdu Dianchun Technology Co., Ltd 400-1166-196 18502815961 cdhxsj@163.com China 14623 60
Shandong Ono Chemical Co., Ltd. 0539-6362799 20) China 10007 58
Beijing OKA biological technology co., LTD 010-62971590 18548936886 3462612863@qq.com China 6912 58
Shanghai kadel chemical technology co., LTD 021-4007787-550 400-7787-550 2850202386@qq.com China 10618 58

4097-04-5(A[5']P5[5']A SODIUM SALT)Related Search:

A[5']P5[5']A SODIUM SALT P1,P5-DI(ADENOSINE-5') PENTAPHOSPHATE SODIUM SALT Adenosine 5'-(hexahydrogen pentaphosphate), 5'->5'-ester with adenosine, pentasodium salt P1,P5-DI(ADENOSINE-5') PENTAPHOSPHATESOD IUM P1,P5-di(adenosine-5')pentaphosphate pentasodium salt 5H2O Adenosine-5'-pentaphosphateε-5'-adenosyl α,β,γ,δ,ε-pentasodium salt A(5′)P5(5′)A P1,P5-Di(adenosine-5′) pentaphosphate pentasodium 5'-ester with adenosine pentasodium salt P1,P5-Di(adenosine-5 P1,P5-Di(adenosine-5') pentaphosphate pentasodium salt Adenosine 5'-(hexahydrogen pentaphosphate) P''''-5'-ester with adenosine pentasodium salt DIADENOSINE PENTAPHOSPHATE SODIUM SALT Diadenosine pentaphosphate pentasodium Diadenosine pentaphosphate pentasodium salt 4097-04-5 C20H24N10O22P55Na Substrate Analogs Nucleosides, Nucleotides, Oligonucleotides Nucleotide Analogs Enzymes, Inhibitors, and Substrates Enzyme Inhibitors Enzyme Inhibitors by Type Biochemicals and Reagents BioChemical