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Tryptamine

Description Applications Plants Containing Tryptamine Pharmacology
Tryptamine
Tryptamine
CAS No.
61-54-1
Chemical Name:
Tryptamine
Synonyms
Tryptamin;TRYPTAMINE;TRIPTAMINE;NSC 165212;L-TRYPTAMINE;TRYPTAMINE(P);AURORA KA-7834;TRYPTAMINE 99+%;TRYPTAMINE 98+%;Indole-ethylamine
CBNumber:
CB8192006
Molecular Formula:
C10H12N2
Formula Weight:
160.22
MOL File:
61-54-1.mol

Tryptamine Properties

Melting point:
113-116 °C(lit.)
Boiling point:
137 °C0.15 mm Hg(lit.)
Density 
0.9787 (rough estimate)
refractive index 
1.6210 (estimate)
Flash point:
185 °C
storage temp. 
2-8°C
solubility 
water: soluble1g/L at 20°C
pka
10.2(at 25℃)
form 
crystalline
color 
white
PH
11.07 (10g/l, H2O, 24.7℃)
Water Solubility 
negligible
Sensitive 
Air Sensitive
Merck 
14,9796
BRN 
125513
CAS DataBase Reference
61-54-1(CAS DataBase Reference)
NIST Chemistry Reference
1H-Indole-3-ethanamine(61-54-1)
EPA Substance Registry System
1H-Indole-3-ethanamine(61-54-1)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi
Risk Statements  20/21/22-36/37/38-41-37/38-22
Safety Statements  24/25-36/37/39-36-26
WGK Germany  3
RTECS  NL4020000
8-23
HazardClass  IRRITANT
HS Code  28259080
HS Code  29339990
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Tryptamine price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 193747 Tryptamine ≥97% 61-54-1 10g $34.4 2018-11-13 Buy
Sigma-Aldrich 193747 Tryptamine ≥97% 61-54-1 50g $117 2018-11-13 Buy
TCI Chemical T0890 Tryptamine >98.0%(HPLC)(T) 61-54-1 25g $64 2017-11-08 Buy
Alfa Aesar A11116 Tryptamine, 98+% 61-54-1 10g $34.2 2018-11-13 Buy
Alfa Aesar A11116 Tryptamine, 98+% 61-54-1 50g $110 2018-11-13 Buy

Tryptamine Chemical Properties,Uses,Production

Description

Tryptamine is a monoamine alkaloid that can be synthesized by decarboxylation of the amino acid tryptophan. Notably, tryptamine can be found in fungi, plants, Amphibia, animals, and microbes.
Tryptamine has an indole ring structure and a fused double ring that is composed of a benzene ring and a pyrrole ring, linked to an amino group by 2-carbon side chain. The indole ring is the vital nucleus of many complex natural products that have significance in drug discovery as well as some synthetic and non-synthetic drugs that are based on tryptamine skeleton.
The chemical’s distinct structure is an approximation to the neurotransmitter serotonin as well-known drugs and hallucinogens. Tryptamine’s significance as psychedelic drugs, neuromodulator, and neurotransmitter is well understood due to its presence in mammalian brain in small amounts.

Applications

Analogs of tryptamine that are typically produced by its synthetic modification play a significant role in individuals due to the introduction of functionalities that are biologically active in its nucleus that may cause changes in the mental and physical status of the human brain.
Substitutions on the indole ring at nitrogen and C-2 of its side chain produce numerous neuroactive compounds ranging from anti-migraine drugs to toxic substances, such as rizatriptan, sumatriptan, and zolmitriptan. A small amount of tryptamine is required due to its fatalities and intoxication for several reasons.

Plants Containing Tryptamine

In plants, tryptamine in small amounts acts as a promising phase to the plant hormone indole-3-acetic acid in one biosynthetic pathway. N, N-dimethyltryptamine (DMT) is a tryptamine derivative that is an active constituent for the hallucinogenic effect of brew known as the “vine of the souls.” Indigenous Amazonian tribes have traditionally used the drink for therapeutic purposes for effective treatment of some physical maladies and abuse disorders. Magic mushrooms are the most common fungi that contain tryptamine derivatives.

Pharmacology

Serotonin (5-hydroxytryptamine, 5-HT), which is a natural derivative of tryptamine is a significant signaling hormone that helps in the modulation and regulation of numerous processes within the central nervous system, for instance, cognition, sleep, temperature regulation, memory, and behavior. The mammalian brain contains small traces of tryptamine, which generally act as a modulator or neurotransmitter by releasing serotonin agents. It is also an enhancer of serotonergic activity. Only one minute is required for tryptamine to produce psychotropic phenomena when used recreationally. It has been associated with fatalities and intoxications for multiple reasons including low toxic concentrations.

Chemical Properties

White to Orange Crystalline Powder

Uses

Occurs in plants.

Uses

psychotropic

Definition

ChEBI: An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position.

Purification Methods

Crystallise tryptamine from *benzene, Et2O (m 114o) or pet ether (m 118o). It has UV: 222n 276, 282 and 291nm (EtOH) and max 226, 275, 281 and 290nm (HCl). [Beilstein 22 II 346, 22 III/IV 4319, 22/10 V 45.]

Tryptamine Preparation Products And Raw materials

Raw materials

Preparation Products


Tryptamine Suppliers

Global( 233)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
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0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20795 55
Mainchem Co., Ltd.
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+86-0592-6210733 sales@mainchem.com CHINA 32764 55
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025-85710122 sales@fine-chemtech.com CHINA 894 55
Shanghai Zheyan Biotech Co., Ltd.
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career henan chemical co
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Zhengzhou JACS Chemical Co., Ltd. 0371-86259281 15981966935
0371-86259281 jacschem@163.com China 379 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
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Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) sh@meryer.com China 40399 62

View Lastest Price from Tryptamine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-06 Tryptamine
61-54-1
US $1.00 / KG 1KG 98% 200KG

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