ChemicalBook >> CAS DataBase List >>1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
- CAS No.
- 84468-24-6
- Chemical Name:
- 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
- Synonyms
- C-1;IQSP;HA-100;HA-100 HYDROCHLORIDE;HA-100 DIHYDROCHLORIDE;1-(5-ISOQUINOLINESULFONYL)PIPERAZINE;1-(5-isoquinolinylsulfonyl)piperazine;1-(5-isoquinolinylsulfonyl)-piperazin;5-(Piperazin-1-ylsulfonyl)isoquinoline;Isoquinoline,5-(1-piperazinylsulfonyl)-
- CBNumber:
- CB8193285
- Molecular Formula:
- C13H15N3O2S
- Molecular Weight:
- 277.34
- MDL Number:
- MFCD00209852
- MOL File:
- 84468-24-6.mol
- MSDS File:
- SDS
Last updated:2023-09-20 16:43:00
| Melting point | >240°C (dec.) |
|---|---|
| Boiling point | 497.4±55.0 °C(Predicted) |
| Density | 1.332±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | DMSO, Methanol, Water |
| form | Off-white lyophilized solid. |
| pka | 7.66±0.10(Predicted) |
| color | Off-White to Pale Yellow |
| CAS DataBase Reference | 84468-24-6(CAS DataBase Reference) |
1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 0543 | C-1 ≥99%(HPLC) | 84468-24-6 | 10 | $163 | 2021-12-16 | Buy |
| Tocris | 0543 | C-1 ≥99%(HPLC) | 84468-24-6 | 50 | $669 | 2021-12-16 | Buy |
| Usbiological | 366887 | HA-100 Dihydrochloride | 84468-24-6 | 25mg | $505 | 2021-12-16 | Buy |
| Usbiological | 254849 | C-1 | 84468-24-6 | 10mg | $409 | 2021-12-16 | Buy |
| ApexBio Technology | B6343 | C-1 | 84468-24-6 | 25mg | $441 | 2021-12-16 | Buy |
1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE Chemical Properties,Uses,Production
Chemical Properties
Pale Yellow Crystalline Solid
Uses
Exhibited potent inhibition toward protein kinase C and cyclic nucleotide dependent protein kinases
Definition
ChEBI: 5-(1-piperazinylsulfonyl)isoquinoline is a member of isoquinolines.
Biological Activity
Inhibitor of protein kinase C. Vasodilator.
Synthesis of 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE from Piperazine and ISOQUINOLINE-5-SULFONYL CHLORIDE
1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 91)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32360 | 55 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Adamas Reagent, Ltd. | 400-6009262 16621234537 | zhangsn@titansci.com | China | 14113 | 59 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 | rs@raise-chem.com | China | 3156 | 55 |
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protein,PKC,Rho-associated kinase,ROCK,kinase,PKG,HA100,inhibit,Inhibitor,Myosin,HA 100,MLCK,HA-100,Rho-associated protein kinase,ROK,PKA,Rho-kinase,Protein kinase C,Protein kinase A
84468-24-6
C13H17Cl2N3O2S
Cell Biology
Cell Signaling and Neuroscience
BioChemical
Kinase/Phosphatase Biology
Protein Kinase A, C and myosin light chain kinase (PKA, PKC and MLCK)
Serine/Threonine Kinase Inhibitors
Protein Kinase Inhibitors and Activators
Protein Kinase