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TYRPHOSTIN B44

TYRPHOSTIN B44 structure

CAS No.: 133550-32-0

Chemical Name:: TYRPHOSTIN B44

Synonyms: AG 527;Zinc03871437;TYRPHOSTIN B44;TYRPHOSTIN AG 527;TRYPHOSTIN AG 527;TYRPHOSTIN B44(-);Reaxys ID: 4356230;ALPHA-CYANO-(-)-(R)-N-(ALPHA-PHENETHYL)-3,4-DIHYDROXYCINNAMIDE;(-)-(r)-n-(α-methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide;(-)-(R)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXYBENZYLIDINECYANOACETAMIDE

CBNumber:: CB8197102

Molecular Formula:: C18H16N2O3

Molecular Weight:: 308.33

MDL Number:: MFCD00209854

MOL File:: 133550-32-0.mol

Last updated:2023-05-18 11:31:14

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TYRPHOSTIN B44 Properties

Boiling point	603.0±55.0 °C(Predicted)
Density	1.299±0.06 g/cm3(Predicted)
storage temp.	−20°C
solubility	DMSO or ethanol: soluble
form	Yellow solid.
pka	8.81±0.10(Predicted)

SAFETY

Risk and Safety Statements

Safety Statements	22-24/25
WGK Germany	3

TYRPHOSTIN B44 price More Price(6)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	T947983	TyrphostinB44,(-)enantiomer	133550-32-0	5mg	$40	2021-12-16	Buy
TRC	T947983	TyrphostinB44,(-)enantiomer	133550-32-0	50mg	$255	2021-12-16	Buy
Usbiological	256987	Tyrphostin B44,	133550-32-0	10mg	$366	2021-12-16	Buy
Usbiological	256986	Tyrphostin B44,	133550-32-0	10mg	$366	2021-12-16	Buy
TRC	T947983	TyrphostinB44,(-)enantiomer	133550-32-0	100mg	$475	2021-12-16	Buy

Product number	Packaging	Price	Buy
T947983	5mg	$40	Buy
T947983	50mg	$255	Buy
256987	10mg	$366	Buy
256986	10mg	$366	Buy
T947983	100mg	$475	Buy

TYRPHOSTIN B44 Chemical Properties,Uses,Production

Uses

Tyrphostin B44, (-) enantiomer is a potent inhibitor of (EGFR) kinase.

Biological Activity

Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC 50 = 0.4 μ M), more active than the (+) enantiomer ((S)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide ). Selective over ErbB2.

TYRPHOSTIN B44 Preparation Products And Raw materials

Raw materials

Preparation Products

TYRPHOSTIN B44 Suppliers

Global( 35)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.	+86-21-54098501	sales@sinch.com.cn	China	11605	64
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35906	56
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
Spectrum Chemical Manufacturing Corp.	021-021-021-67601398-809-809-809 15221380277	marketing_china@spectrumchemical.com	China	9664	60
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58

Supplier	Advantage
Amadis Chemical Company Limited	58
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.	64
J & K SCIENTIFIC LTD.	76
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Wuhan Chemwish Technology Co., Ltd	56
VDM Biochemicals	64
Spectrum Chemical Manufacturing Corp.	60
BOC Sciences	65
EMMX Biotechnology LLC	60
Shanghai EFE Biological Technology Co., Ltd.	58

133550-32-0(TYRPHOSTIN B44)Related Search:

TYRPHOSTIN B44, (+) ENANTIOMER N1-ISOPROPYL-2-CYANOACETAMIDE D,L-N-(ALPHA-PHENYLETHYL) METHACRYLAMIDE AG 99 3-(1-PHENYLETHYLAMINO)PROPANENITRILE

TYRPHOSTIN B44 (R)-(+)-N-ALLYL-ALPHA-METHYLBENZYLAMINE& N-ISOPROPYLMETHACRYLAMIDE AG 490 BENZYL-((E)-3-PHENYL-ALLYL)-AMINE

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(R)-(E)-2-CYANO-3-(3',4'-DIHYDROXYPHENYL)-N-(1-PHENYLETHYL)-2-PROPENAMIDE (-)-(R)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXY-BENZYLIDENECYANOACETAMIDE (-)-(R)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXYBENZYLIDINECYANOACETAMIDE TYRPHOSTIN AG 527 TYRPHOSTIN B44 TYRPHOSTIN B44(-) TRYPHOSTIN AG 527 AG 527 ALPHA-CYANO-(-)-(R)-N-(ALPHA-PHENETHYL)-3,4-DIHYDROXYCINNAMIDE (-)-(r)-n-(α-methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide Tyrphostin B44, (-)-(R)-N-(α-Methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide Zinc03871437 (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phenylethyl]-2-propenamide Reaxys ID: 4356230 2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phenylethyl]-, (2E)- 133550-32-0 BioChemical Cell Signaling and Neuroscience Cell Biology Receptor Tyrosine Kinase Inhibitors Epidermal Growth Factor Receptor (EGFR) Kinase/Phosphatase Biology Intracellular Signaling Protein Kinase