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Pyridoxine

Description References
Pyridoxine
Pyridoxine structure
CAS No.
65-23-6
Chemical Name:
Pyridoxine
Synonyms
Beesix;PN HCL;VIT B6;B6-HCL;Bezatin;Adermin;Hydoxin;Hexabion;Gravidox;ADERMINE
CBNumber:
CB8197940
Molecular Formula:
C8H11NO3
Formula Weight:
169.18
MOL File:
65-23-6.mol

Pyridoxine Properties

Melting point:
214-215 °C(lit.)
Boiling point:
298.46°C (rough estimate)
Density 
1.2435 (rough estimate)
refractive index 
1.5100 (estimate)
storage temp. 
2-8°C
solubility 
H2O: 0.1 g/mL at 20 °C, clear, colorless
pka
pKa 5.00(H2O t = 25.0 I = 0.15 (mixed)) (Uncertain)
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
LXNHXLLTXMVWPM-UHFFFAOYSA-N
CAS DataBase Reference
65-23-6(CAS DataBase Reference)
NIST Chemistry Reference
2-Methyl-3-hydroxy-4,5-dihydroxymethylpyridine(65-23-6)
EPA Substance Registry System
3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-(65-23-6)

SAFETY

Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  UV1350000
8-10
HS Code  29362500

Pyridoxine price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P5669 Pyridoxine ≥98% 65-23-6 5g $55.1 2018-11-13 Buy
Sigma-Aldrich P5669 Pyridoxine ≥98% 65-23-6 25g $92.1 2018-11-13 Buy
Cayman Chemical 20706 Pyridoxine ≥98% 65-23-6 5g $25 2018-11-19 Buy
Cayman Chemical 20706 Pyridoxine ≥98% 65-23-6 10g $38 2018-11-19 Buy
Cayman Chemical 20706 Pyridoxine ≥98% 65-23-6 25g $81 2018-11-19 Buy

Pyridoxine Chemical Properties,Uses,Production

Description

Pyridoxine hydrochloride provides pyridoxine, which is also known as vitamin B6. Vitamin B6 is naturally found in foods such as cereals, beans, vegetables, liver, meat, and eggs.  Vitamin B6 functionalizes as a coenzyme in the metabolism of protein, carbohydrate, and fat. Vitamin 6 is needed to maintain the health of nerves, skin, and red blood cells.
Pyridoxine is used to prevent or treat vitamin B6 deficiency caused by inadequate dietary intake. It is also used to treat drug induced deficiency in patients taking isoniazid or oral contraceptives.

References

[1] http://www.webmd.com
[2] https://dailymed.nlm.nih.gov

Chemical Properties

crystalline solid

Uses

antibacterial

Uses

A form of vitamin B6

Uses

pyridoxine HCL is a skin-conditioning agent that is also widely used in hair products.

Uses

Vitamin B6, a water-soluble vitamin with a solubility of 1 g in 5 ml of water. It functions in the utilization of protein and is an essential nutrient in enzyme reactions. It is necessary for proper growth. During processing, there is a loss due to leaching of the vitamin in water. It is destroyed by high temperatures, high irradiation, and exposure to light. During storage, loss increases with temperature and storage time. It is found in liver, eggs, and meats.

Definition

ChEBI: A hydroxymethylpyridine with hydroxymethyl groups at positions 4 and 5, a hydroxy group at position 3 and a methyl group at position 2. The 4-methanol form of vitamin B6, it is converted intoto pyridoxal phosphate which is a coenzyme f r synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid.

brand name

Hexa-Betalin (Lilly).

World Health Organization (WHO)

Pyridoxine (vitamin B6) is listed in theWHO Model List of Essential Drugs.

General Description

The discovery of vitamin B6 is generally ascribed to Paul Gy?rgy who first realized there was a vitamin that was distinctly different from vitamin B2 in 1934. Pyridoxine (PN) is the C4 hydroxymethyl derivative, pyridoxal (PL) is the C4 formyl derivative and pyridoxamine (PM) is the C4 aminomethyl derivative of 5-(hydroxymethyl)- 2-methylpyridin-3-ol). Each of these are also converted to their corresponding 5'-phosphate derivatives referred to as pyridoxine 5'-phosphate (PNP), pyridoxal 5'-phosphate (PLP), and pyridoxamine 5'-phosphate (PMP), respectively . Because of their ability to interconvert, all are considered active forms of vitamin B6 in vivo. Although PLP is the major coenzyme form, PMP can also function as a coenzyme primarily in aminotransferases. The major metabolite is 4-pyridoxic acid, which is excreted in the urine.

Clinical Use

Pyridoxine is indicated in the treatment and prevention of known or suspected vitamin B6 deficiency, which is most likely to occur in the setting of alcoholism in developed countries. At least seven genetic disorders that result in a vitamin B6 deficiency syndrome in the presence of an adequate dietary intake have been identified. These result from defects in enzymes that are responsible for the bioactivation or utilization of vitamin B6.

Safety Profile

Moderately toxic by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Human systemic effects: ataxia, local anesthetic, paresthesia. When heated to decomposition it emits toxic fumes of Nox

Veterinary Drugs and Treatments

Pyridoxine use in veterinary medicine is relatively infrequent. It may be of benefit in the treatment of isoniazid (INH) or crimidine (an older rodenticide) toxicity. Pyridoxine deficiency is apparently extremely rare in dogs or cats able to ingest food. Cats with severe intestinal disease may have a greater requirement for pyridoxine in their diet. Experimentally, pyridoxine has been successfully used in dogs to reduce the cutaneous toxicity associated with doxorubicin containing pegylated liposomes (Doxil?). Pyridoxine has been demonstrated to suppress the growth of feline mammary tumors (cell line FRM) in vitro.
In humans, labeled uses for pyridoxine include pyridoxine deficiency and intractable neonatal seizures secondary to pyridoxine dependency syndrome. Unlabeled uses include premenstrual syndrome (PMS), carpal tunnel syndrome, tardive dyskinesia secondary to antipsychotic drugs, nausea and vomiting in pregnancy, hyperoxaluria type 1 and oxalate kidney stones, and for the treatment of isoniazid (INH), cycloserine, hydrazine or Gyometra mushroom poisonings.

Pyridoxine Preparation Products And Raw materials

Raw materials

Preparation Products


Pyridoxine Suppliers

Global( 218)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shaanxi Yikanglong Biotechnology Co., Ltd.
17791478691
yklbiotech@163.com CHINA 297 58
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19917 60
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 892 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1849 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 27142 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23964 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28237 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 8260 58

View Lastest Price from Pyridoxine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-07-03 Pyridoxine
65-23-6
US $1.00 / KG 1KG 98% 1kg,5kg,100kg career henan chemical co
2018-10-07 Pyridoxine
65-23-6
US $1.00 / KG 1KG 99%(Customizable specifications) 800kg Shaanxi Yikanglong Biotechnology Co., Ltd.

65-23-6(Pyridoxine)Related Search:


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