4'-Hydroxyvalerophenone
- CAS No.
- 2589-71-1
- Chemical Name:
- 4'-Hydroxyvalerophenone
- Synonyms
- p-Valerylphenol;4-VALERYL-PHENOL;4-PENTANOYLPHENOL;4'- hydroxyketone;4-Hydroxyvaleropheno;4'-hydroxy-pentanone;Hydroxyvalerophenone;P-HYDROXYVALEROPHENONE;4-HYDROXYVALEROPHENONE;p-Hydroxypentanophenone
- CBNumber:
- CB8203348
- Molecular Formula:
- C11H14O2
- Molecular Weight:
- 178.23
- MDL Number:
- MFCD00009719
- MOL File:
- 2589-71-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4′-Hydroxyvalerophenone 98% | 245143 | 25g | $180 |
| 4'-Hydroxyvalerophenone >98.0%(T) | H0627 | 25g | $118 |
| 4'-Hydroxyvalerophenone >98.0%(T) | H0627 | 500g | $1092 |
| 4''-Hydroxyvalerophenone | H995618 | 5g | $65 |
| 4'-Hydroxyvalerophenone 98% | JK235759 | 25g | $75 |
| More product size | |||
| Melting point | 62-65 °C |
|---|---|
| Boiling point | 182-183 °C/3 mmHg(lit.) |
| Density | 1.0292 (rough estimate) |
| refractive index | 1.5390 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 8.13±0.15(Predicted) |
| form | powder to crystal |
| color | White to Orange to Green |
| InChI | InChI=1S/C11H14O2/c1-2-3-4-11(13)9-5-7-10(12)8-6-9/h5-8,12H,2-4H2,1H3 |
| InChIKey | ZKCJJGOOPOIZTE-UHFFFAOYSA-N |
| SMILES | C(C1=CC=C(O)C=C1)(=O)CCCC |
| CAS DataBase Reference | 2589-71-1(CAS DataBase Reference) |
| FDA UNII | RFV916NJJ6 |
| NIST Chemistry Reference | 1-Pentanone, 1-(4-hydroxyphenyl)-(2589-71-1) |
| EPA Substance Registry System | 1-Pentanone, 1-(4-hydroxyphenyl)- (2589-71-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25-37/39-26 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29182900 | |||||||||
| NFPA 704 |
|
4'-Hydroxyvalerophenone price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 245143 | 4′-Hydroxyvalerophenone 98% | 2589-71-1 | 25g | $180 | 2023-06-20 | Buy |
| TCI Chemical | H0627 | 4'-Hydroxyvalerophenone >98.0%(T) | 2589-71-1 | 25g | $118 | 2026-04-30 | Buy |
| TCI Chemical | H0627 | 4'-Hydroxyvalerophenone >98.0%(T) | 2589-71-1 | 500g | $1092 | 2026-04-30 | Buy |
| TRC | H995618 | 4''-Hydroxyvalerophenone | 2589-71-1 | 5g | $65 | 2021-12-16 | Buy |
| Frontier Specialty Chemicals | JK235759 | 4'-Hydroxyvalerophenone 98% | 2589-71-1 | 25g | $75 | 2021-12-16 | Buy |
4'-Hydroxyvalerophenone Chemical Properties,Uses,Production
Chemical Properties
white to light beige powder
Uses
4'-Hydroxyvalerophenone is an organic intermediate and pharmaceutical intermediate for the preparation of acylphenoxyacetic acid compounds.
Preparation
4'-Hydroxyvalerophenone is synthesized from phenol and valeryl chloride. It is a raw material intermediate for liquid crystals.
Synthesis Reference(s)
Tetrahedron Letters, 35, p. 6537, 1994 DOI: 10.1016/S0040-4039(00)78266-9
Synthesis
638-29-9
108-95-2
2589-71-1
GENERAL METHOD: Phenol (0.28 mmol) was dissolved in trifluoromethanesulfonic acid (TfOH, 3 mL) with n-pentanoyl chloride (0.28 mmol) at 0 °C. The reaction mixture was gradually warmed up to room temperature according to the conditions shown in Table 2 and kept for an appropriate time. After completion of the reaction, the mixture was poured into a mixture of ice water and ethyl acetate. The organic layer was separated and washed sequentially with 1 M hydrochloric acid, saturated sodium bicarbonate solution and saturated sodium chloride solution. The organic layer was dried over anhydrous magnesium sulfate and filtered, and the filtrate was concentrated. The crude product was purified by silica gel column chromatography to give 4-hydroxyvalerophenone. The spectral data of all the products were in agreement with those reported in the literature.
References
[1] Tetrahedron, 2011, vol. 67, # 3, p. 641 - 649
[2] Chemische Berichte, 1985, vol. 118, # 8, p. 3332 - 3349
[3] Tetrahedron, 1981, vol. 37, # 16, p. 2815 - 2821
[4] Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 1998, vol. 54, # 2, p. 285 - 297
[5] Bioorganic and Medicinal Chemistry Letters, 2001, vol. 11, # 6, p. 841 - 844
4'-Hydroxyvalerophenone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2176 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Hebei Yiduo Import and Export Co., Ltd. | joycedemei1505@outlook.com | China | 215 | 58 | |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13843 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21590 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29819 | 58 |
| Cangzhou Wanyou New Material Technology Co.,Ltd | 18631714998 | sales@czwytech.com | CHINA | 904 | 58 |
| Shanghai Longyu Biotechnology Co., Ltd. | +8619521488211 | info@longyupharma.com | China | 2542 | 58 |
View Lastest Price from 4'-Hydroxyvalerophenone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-20 | 4'-Hydroxyvalerophenone
2589-71-1
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-06-27 | 4'-Hydroxyvalerophenone
2589-71-1
|
US $0.00 / KG | 1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-06-20 | 4-Hydroxyvalerophenone
2589-71-1
|
US $0.00 / KG | 1KG | 0.99 | 25kg | Hebei Yanxi Chemical Co., Ltd. |
-
- 4'-Hydroxyvalerophenone
2589-71-1
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 4'-Hydroxyvalerophenone
2589-71-1
- US $0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 4-Hydroxyvalerophenone
2589-71-1
- US $0.00 / KG
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
