ChemicalBook >> CAS DataBase List >>5-Amino-2,4,6-triiodoisophthaloyl dichloride
5-Amino-2,4,6-triiodoisophthaloyl dichloride
- CAS No.
- 37441-29-5
- Chemical Name:
- 5-Amino-2,4,6-triiodoisophthaloyl dichloride
- Synonyms
- 5-AMINO-2,4,6-TRIIODOISOPHTHALOYL DICHLORIDE;5-Amino-2,4,6-triiodoisophthalic acid dichloride;ATIPA-DICL;ATIPA DICHLORIDE;Iohexol Impurity 9;5-Amino-2,4,6- trii; Iohexol Impurity L;5-Amino-2,4,6-Triodoisophthalo;Amino triiodisophthaloyl dichloride;5-amino-2,4,6-triiodisophthaloyl dichlor
- CBNumber:
- CB8206516
- Molecular Formula:
- C8H2Cl2I3NO2
- Molecular Weight:
- 595.73
- MDL Number:
- MFCD00270836
- MOL File:
- 37441-29-5.mol
Last updated:2023-12-04 16:56:25
| Melting point | 231°C(lit.) |
|---|---|
| Boiling point | 566.9±50.0 °C(Predicted) |
| Density | 2.826±0.06 g/cm3(Predicted) |
| vapor pressure | 0.018Pa at 20℃ |
| storage temp. | Refrigerator, under inert atmosphere |
| solubility | Acetone (Slightly), Methanol (Very Slightly) |
| pka | -3.45±0.10(Predicted) |
| form | Solid |
| color | Yellow toDark Brown |
| λmax | 233nm(MeOH)(lit.) |
| LogP | 3.7 at 20℃ |
| CAS DataBase Reference | 37441-29-5(CAS DataBase Reference) |
| EWG's Food Scores | 1-2 |
| FDA UNII | 9OP12587AJ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H317-H319-H411 | |||||||||
| Precautionary statements | P261-P264-P272-P273-P280-P302+P352+P333+P313+P363-P305+P351+P338+P337+P313-P391-P501 | |||||||||
| Hazard Codes | Xi,N | |||||||||
| Risk Statements | 43-51/53 | |||||||||
| Safety Statements | 22-36/37-61 | |||||||||
| RIDADR | 3077 | |||||||||
| HS Code | 2922.49.3700 | |||||||||
| HazardClass | 9 | |||||||||
| PackingGroup | III | |||||||||
| NFPA 704 |
|
5-Amino-2,4,6-triiodoisophthaloyl dichloride price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A2854 | 5-Amino-2,4,6-triiodoisophthaloyl Dichloride >98.0%(T) | 37441-29-5 | 5g | $156 | 2024-03-01 | Buy |
| TCI Chemical | A2854 | 5-Amino-2,4,6-triiodoisophthaloyl Dichloride >98.0%(T) | 37441-29-5 | 25g | $542 | 2024-03-01 | Buy |
| TRC | A630815 | 5-Amino-2,4,6-triiodoisophthaloyl Dichloride | 37441-29-5 | 250mg | $130 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA05533 | 5-Amino-2,4,6,-triiodoisophthaloyl dichloride | 37441-29-5 | 100g | $600 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0024319 | 5-AMINO-2,4,6-TRIIODISOPHTHALOYL ACID DICHLORIDE 95.00% | 37441-29-5 | 2.5G | $1947 | 2021-12-16 | Buy |
5-Amino-2,4,6-triiodoisophthaloyl dichloride Chemical Properties,Uses,Production
Description
5-Amino-2,4,6-triiodoisophthaloyl dichloride is a triiodinated compound that has been shown to bind to the receptor for asialoglycoprotein. It is used in the diagnosis of liver and kidney diseases. 5-Amino-2,4,6-triiodisophthaloyl acid dichloride is taken up by tissues and organs and causes damage to these tissues. The chloride ion binds to the molecule, making it more water soluble. The lactobionic acid residue is then cleaved off by an enzyme in the cell called beta-galactosidase. This leaves a molecule containing iodine which can be detected with a diagnostic technique such as X-ray crystallography or nuclear magnetic resonance spectroscopy.
Chemical Properties
Yellow Solid
Uses
5-Amino-2,4,6- triiodisophthaloyl acid dichloride is used in the preparation of trimeric X-ray contrast agents.
Preparation
5-Amino-2,4,6-triiodo-isophtalic acid (30 g, 0.054 mol), thionyl chloride (8.2 ml, 0.113 mol) and pyridine (0.2 ml) in 1 ,2 dichloroethane (20 ml) were heated to 70 ℃. A portion of thionyl chloride (15.2 ml, 0.21 mol) was added dropwise during 2 h, and the mixture was heated to 85 ℃ for 6 h. After cooling the reaction mixture to room temperature, it was poured into 300 g of ice-water. The yellow precipitate was filtered off, sucked dry and then washed with water until pH=5. The filter cake was then dried in a vacuum oven for 3 hrs. A light yellow powder was obtained as 5-Amino-2,4,6-triiodisophthaloyl acid dichloride.
Flammability and Explosibility
Not classified
Synthesis of 5-Amino-2,4,6-triiodoisophthaloyl dichloride from 5-Amino-2,4,6-triiodoisophthalic acid
5-Amino-2,4,6-triiodoisophthaloyl dichloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 289)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Yutian pharmaceutical Co.,Ltd. | +undefined-0518-86098006 +undefined19851887368 | lvan.hui@jsytsw.com | China | 80 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
View Lastest Price from 5-Amino-2,4,6-triiodoisophthaloyl dichloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-25 | 5-Amino-2,4,6-triiodoiso phthaloyl dichloride
37441-29-5
|
US $90.90 / Kg/Drum | 25Kg/Drum | 98.00%HPLC | 2tons/month | Asia Chem I and E (Jiangsu) Co Ltd | |
 |
2022-09-16 | 5-Amino-2,4,6-triiodoisophthaloyl chloride
37441-29-5
|
US $30.00-28.00 / Kg | 1Kg | 99.0% up | 50 tons per month | Xinxiang Hongqi District Houyuan Trading Co.,Ltd | |
 |
2021-12-21 | 5-Amino-2,4,6- Triiodisophthaloyl Acid Dichloride
37441-29-5
|
US $10.00 / KG | 1KG | ≥98% | 100tons | Qiuxian Baitai New Material Co., LTD |
-
- 5-Amino-2,4,6-triiodoiso phthaloyl dichloride
37441-29-5
- US $90.90 / Kg/Drum
- 98.00%HPLC
- Asia Chem I and E (Jiangsu) Co Ltd
-
- 5-Amino-2,4,6-triiodoisophthaloyl chloride
37441-29-5
- US $30.00-28.00 / Kg
- 99.0% up
- Xinxiang Hongqi District Houyuan Trading Co.,Ltd
-
- 5-Amino-2,4,6- Triiodisophthaloyl Acid Dichloride
37441-29-5
- US $10.00 / KG
- ≥98%
- Qiuxian Baitai New Material Co., LTD
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oyl acid dichloride
37441-29-5
C8H2Cl2I3NO2
Intermediate of Ioversol