ChemicalBook >> CAS DataBase List >>3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one

3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one

CAS No.
51225-30-0
Chemical Name:
3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
Synonyms
Wighteone;Erythrinin B;5,7,4'-Trihydroxy-6-prenylisoflavone;4',5,7-Trihydroxy-6-prenyl-isoflavone;4',5,7-Trihydroxy-6-(3-methyl-2-butenyl)isoflavone;5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methylbut-2-enyl)chromen-4-one;5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methylbut-2-enyl)-1-benzopyran-4-one;5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one;3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-
CBNumber:
CB82324582
Molecular Formula:
C20H18O5
Molecular Weight:
338.35
MDL Number:
MFCD06796682
MOL File:
51225-30-0.mol
Last updated:2023-05-15 10:43:29

3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one Properties

Melting point 227 °C(Solv: methanol (67-56-1))
Boiling point 586.1±50.0 °C(Predicted)
Density 1.351±0.06 g/cm3(Predicted)
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form powder
pka 7.03±0.20(Predicted)
color Yellow
Stability Light Sensitive
FDA UNII 48ZS74CB9A

3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC W499205 Wighteone 51225-30-0 1mg $70 2021-12-16 Buy
TRC W499205 Wighteone 51225-30-0 5mg $275 2021-12-16 Buy
TRC W499205 Wighteone 51225-30-0 25mg $935 2021-12-16 Buy
Biosynth Carbosynth FW138624 Wighteone 51225-30-0 10mg $1200 2021-12-16 Buy
American Custom Chemicals Corporation PXT0000273 WIGHTEONE 95.00% 51225-30-0 10G $1334.03 2021-12-16 Buy
Product number Packaging Price Buy
W499205 1mg $70 Buy
W499205 5mg $275 Buy
W499205 25mg $935 Buy
FW138624 10mg $1200 Buy
PXT0000273 10G $1334.03 Buy

3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one Chemical Properties,Uses,Production

Uses

Wighteone is a natural product derivative of Genistein (G350000). Genistein exhibits specific inhibitory activity against tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol.

Definition

ChEBI: A member of the class of 7-hydroxyisoflavones that is isoflavone substituted by hydroxy groups at positions 5, 7 and 4' and a prenyl group at position 6. It has been isolated from Ficus mucuso.

target

HSP (e.g. HSP90) | Antifection

446-72-0
51225-30-0
Synthesis of 3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one from Genistein

3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one Preparation Products And Raw materials

3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one Suppliers

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View Lastest Price from 3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Wighteone pictures 2023-02-24 Wighteone
51225-30-0
US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
  • Wighteone pictures
  • Wighteone
    51225-30-0
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one 4',5,7-Trihydroxy-6-(3-methyl-2-butenyl)isoflavone 4',5,7-Trihydroxy-6-prenyl-isoflavone 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one Erythrinin B Wighteone 5,7,4'-Trihydroxy-6-prenylisoflavone 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methylbut-2-enyl)-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)- 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methylbut-2-enyl)chromen-4-one 51225-30-0