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4-Methylpyrazole

4-Methylpyrazole
4-Methylpyrazole structure
CAS No.
7554-65-6
Chemical Name:
4-Methylpyrazole
Synonyms
Antizol;fomepizol;FOMEPIZOLE;Antizol-Vet;AKOS B014452;Antizol (TN);4-Methylpyrazol;4-methyl-pyrazol;4-METHYLPYRAZOLE;4-METHYLPYRRAZOLE
CBNumber:
CB8233079
Molecular Formula:
C4H6N2
Formula Weight:
82.1
MOL File:
7554-65-6.mol

4-Methylpyrazole Properties

Melting point:
13°C
Boiling point:
99-100 °C6 mm Hg(lit.)
Density 
0.993 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.495(lit.)
Flash point:
205 °F
storage temp. 
2-8°C
solubility 
soluble
form 
Liquid After Melting
color 
Clear colorless to yellow
Specific Gravity
0.993
Water Solubility 
soluble
Sensitive 
Hygroscopic
Merck 
14,4226
BRN 
105204
CAS DataBase Reference
7554-65-6(CAS DataBase Reference)
NIST Chemistry Reference
4-methylpyrazole(7554-65-6)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26-36-24/25
RIDADR  2810
WGK Germany  3
RTECS  UQ7350000
10-23
HazardClass  6.1(b)
PackingGroup  III
HS Code  29331990
Toxicity LD50 (7 days) in mice, rats (mmol/kg): 3.8, 3.8 i.v.; 7.8, 6.5 orally (Magnusson)
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
P501 Dispose of contents/container to..…

4-Methylpyrazole price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 222569 Fomepizole 99% 7554-65-6 1g $79.3 2018-11-13 Buy
Sigma-Aldrich 222569 Fomepizole 99% 7554-65-6 5g $274 2018-11-13 Buy
TCI Chemical M0774 4-Methylpyrazole >98.0%(GC) 7554-65-6 1g $88 2018-11-22 Buy
TCI Chemical M0774 4-Methylpyrazole >98.0%(GC) 7554-65-6 5g $265 2018-11-22 Buy
Alfa Aesar A18083 4-Methyl-1H-pyrazole, 97+% 7554-65-6 1g $67.9 2018-11-13 Buy

4-Methylpyrazole Chemical Properties,Uses,Production

Description

Fomepizole is the first drug indicated as an antidote for ethylene glycol poisoning (it has also shown promise as a treatment for methanol poisoning). Fomepizole is 4-methyl-1H-pyrazole active as a synthetic alcohol dehydrogenase inhibitor, blocking the formation of toxic ethylene glycol metabolites which are responsible for a severe metabolic acidosis and renal failure. In limited human studies, it reversed the toxicity of potentially lethal doses of ethylene glycol. The main urinary metabolite has been reported to be 4-carboxypyrazole by oxidation of the methyl group. Compared with the current treatment (ethanol), the duration of action is longer and the safety is improved, with no toxic effects reported.

Chemical Properties

clear colourless to yellowish liquid after melting

Originator

Orphan Medical (US)

Uses

Useful as an antidote in methanol and ethylene glycol poisoning.

Uses

Antidote in methanol or ethylene glycol poisoning;Alcohol dehydrogenase inhibitor

Uses

antidote to ethylene glycol or methanol poisoning

Definition

ChEBI: A member of the class of pyrazoles that is 1H-pyrazole substituted by a methyl group at position 4.

brand name

Antizol (Jazz).

4-Methylpyrazole Preparation Products And Raw materials

Raw materials

Preparation Products


4-Methylpyrazole Suppliers

Global( 196)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19917 60
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32451 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070;product@chemlin.com.cn
product@chemlin.com.cn CHINA 3015 60
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 25795 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23958 58
Hubei Jusheng Technology Co.,Ltd.
8615527864001
sales@jushengtech.com CHINA 20084 58
Accela ChemBio Inc.
(+1)-858-699-3322
(+1)-858-876-1948 info@accelachem.com United States 12233 58
Nanjing ShengSai Chemical Co., Ltd. 13951876367
025-85205967 sales@shengsaichem.com China 306 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
PharmaBlock Sciences (Nanjing),Inc. 400 025 5188
86-025-86918232 sales_china@pharmablock.com China 6448 55

View Lastest Price from 4-Methylpyrazole manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-19 4-Methylpyrazole
7554-65-6
US $1.00 / kg 1kg 99% Customized career henan chemical co

4-Methylpyrazole Spectrum


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