ChemicalBook >> CAS DataBase List >>TAFENOQUINE SUCCINATE
TAFENOQUINE SUCCINATE
- CAS No.
- 106635-81-8
- Chemical Name:
- TAFENOQUINE SUCCINATE
- Synonyms
- SB-252263;WR-238605;Krintafel;SB 252263AX;Wr238605 succinate;Tafenoquine Succinate;N-[2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine;Parasite,inhibit,WR-238605,Inhibitor,Tafenoquine Succinate,Tafenoquine,WR238605,WR 238605;N4-(2,6-Dimethoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)quinolin-8-yl)pentane-1,4-diamine succinate(1:1);8-[(4-Amino-1-methylbutyl)amino]-2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinoline succinate
- CBNumber:
- CB82360531
- Molecular Formula:
- C28H34F3N3O7
- Molecular Weight:
- 581.5806696
- MDL Number:
- MFCD00892249
- MOL File:
- 106635-81-8.mol
Last updated:2023-09-20 16:43:00
| Melting point | 146-149° |
|---|---|
| storage temp. | 2-8°C |
| solubility | DMSO: soluble5mg/mL (clear solution) |
| form | powder |
| color | white to beige |
| FDA UNII | DL5J0B8VSS |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| WGK Germany | 3 |
| Toxicity | LD50 in male, female rats (mg/kg): 102, 71 i.p.; 429, 416 orally (LaMontagne) |
TAFENOQUINE SUCCINATE price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0396 | Tafenoquine succinate ≥95% (HPLC) | 106635-81-8 | 10mg | $93.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0396 | Tafenoquine succinate ≥95% (HPLC) | 106635-81-8 | 50mg | $380 | 2024-03-01 | Buy |
| TRC | T004760 | Tafenoquine succinate | 106635-81-8 | 10mg | $275 | 2021-12-16 | Buy |
| ChemScene | CS-0083862 | Tafenoquine succinate 99.98% | 106635-81-8 | 10mg | $290 | 2021-12-16 | Buy |
| ChemScene | CS-0083862 | Tafenoquine succinate 99.98% | 106635-81-8 | 5mg | $190 | 2021-12-16 | Buy |
TAFENOQUINE SUCCINATE Chemical Properties,Uses,Production
Uses
Tatenoquine is a new 8-aminoquinoline with an improved therapeutic index and safety profile as compared to primaquine (P733500).Tafenoquine has the potential to become a widely used drug in the prevention and treatment of malaria infection and could replace some currently used drugs as resistant strains of Plasmodium species increase.
Uses
Tafenoquine succinate is a new 8-aminoquinoline with an improved therapeutic index and safety profile as compared to primaquine (P733500).Tafenoquine has the potential to become a widely used drug in the preven tion and treatment of malaria infection and could replace some currently used drugs as resistant strains of Plasmodium species increase.
Biochem/physiol Actions
Tafenoquine is an antimalarial primaquine analog being investigated to treat and prevent Plasmodium vivax infections. It can eliminate both blood and liver stages of Plasmodium vivax. Tafenoquine has also been tested as a therapy for leishmaniasis.
TAFENOQUINE SUCCINATE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 45)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 +86-13986145403 | info@fortunachem.com | China | 5986 | 58 |
| Guangzhou TongYi biochemistry technology Co.,LTD | +8613073028829 | mack@tongyon.com | China | 2996 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. | 17702719238 17702719238 | sales@sun-shinechem.com | China | 905 | 64 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 | sales-cpd@caerulumpharma.com | China | 3419 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
View Lastest Price from TAFENOQUINE SUCCINATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-09-29 | Tafenoquine succinate
106635-81-8
|
US $0.00-0.00 / g | 1g | 98.0% | 1kg/month | WUHAN FORTUNA CHEMICAL CO., LTD |
-
- Tafenoquine succinate
106635-81-8
- US $0.00-0.00 / g
- 98.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
WR-238605
Butanedioic acid, compd. with N(sup 4)-(2,6-dimethoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)-8-quinolinyl)-1,4-pentanediamine (1:1)
Wr238605 succinate
Tafenoquine Succinate
N-[2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine
SB-252263
SB 252263AX
8-[(4-Amino-1-methylbutyl)amino]-2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinoline succinate
N4-(2,6-Dimethoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)quinolin-8-yl)pentane-1,4-diamine succinate(1:1)
TAFENOQUINE SUCCINATE; WR-238605, WR 238605, WR238605, SB-252263-AAB; SB252263-AAB; SB 252263-AAB; KRINTAFEL;
Krintafel
Parasite,inhibit,WR-238605,Inhibitor,Tafenoquine Succinate,Tafenoquine,WR238605,WR 238605
106635-81-8
C24H28F3N3O3C4H6O4