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Esculin

CAS No.
531-75-9
Chemical Name:
Esculin
Synonyms
ESCULIN;Escosyl;BICOLOIN;AESCULIN;POLYDROM;Esculine;Bicolorin;Crataegin;Polychrom;vitaminc2
CBNumber:
CB8245061
Molecular Formula:
C15H16O9
Molecular Weight:
340.28
MDL Number:
MFCD00006879
MOL File:
531-75-9.mol
MSDS File:
SDS
Last updated:2024-03-26 17:16:27

Esculin Properties

Melting point 203 °C
alpha -88 º (c=2,dioxane/water1:1)
Boiling point 396.1°C (rough estimate)
Density 0.791 g/mL at 20 °C
vapor pressure 0Pa at 25℃
refractive index -79 ° (C=2.4, 50% Dioxane)
Flash point 15 °C
storage temp. 2-8°C
solubility methanol: 50 mg/mL hot, clear to very faintly turbid, yellow-green fluoresc.
pka 7.00±0.20(Predicted)
form Liquid
color Clear
optical activity [α]20/D 41±2°, c = 5% in pyridine
Water Solubility MODERATELY SOLUBLE
Merck 3698
Stability Stable. Incompatible with strong oxidizing agents.
InChIKey YRABYCJKUBFWQY-FHXAZYNBSA-N
LogP -1.307 (est)
CAS DataBase Reference 531-75-9(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 1Y1L18LQAF
NIST Chemistry Reference 7-Hydroxy-2-oxo-2h-chromen-6-yl hexopyranoside(531-75-9)
EPA Substance Registry System Esculin (531-75-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312+P330-P501
Hazard Codes  F,C,Xi
Risk Statements  11-20/21/22-34-68/20/21/22-36/37/38
Safety Statements  26-36/37/39-45-24/25-36/37-16
RIDADR  UN 2924 3/PG 2
WGK Germany  3
RTECS  DJ3085000
3-10-23
HS Code  29389090

Esculin price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E8250 Esculin hydrate ≥98% 531-75-9 5g $58.4 2024-03-01 Buy
Sigma-Aldrich 02350 Esculin hydrate ≥98.0%(HPLC) 531-75-9 10g $83.6 2024-03-01 Buy
Sigma-Aldrich 02350 Esculin hydrate ≥98.0%(HPLC) 531-75-9 50g $302 2024-03-01 Buy
Sigma-Aldrich 06212 Esculin hydrate analytical standard 531-75-9 100mg $75.4 2022-05-15 Buy
Sigma-Aldrich Y0001612 Esculin European Pharmacopoeia (EP) Reference Standard 531-75-9 y0001612 $153 2024-03-01 Buy
Product number Packaging Price Buy
E8250 5g $58.4 Buy
02350 10g $83.6 Buy
02350 50g $302 Buy
06212 100mg $75.4 Buy
Y0001612 y0001612 $153 Buy

Esculin Chemical Properties,Uses,Production

Description

Aesculin (also Esculin) is a glucoside compound, which occurs naturally in unprocessed seeds, leaves, bark, and flowers of horse chestnut. Aesculin is used for the identification of bacteria, for the treatment of hemorrhoids and venous peripheral diseases. In cosmetics, aesculin was found to be effective in the treatment of aging skin. Owing to its ultraviolet absorbing activity, aesculin is employed in tanning preparations. Aesculin can be also used as a substrate for the detection of ß-gluocosidase activity in polyacrylamide gels.

References

[1] Anna D. Orla-Jensen, About the application of aesculin for the identification of bacteria, APMIS, 1934, vol. 11, 312-322
[2] S. Srijayanta, A. Raman and B. L. Goodwin, A comparative study of the constituents of Aesculus hippocastanum and Aesculus indica, Journal of Medical Food, 1999, vol. 2, 45-50
[3] Ki-Sun Kwon, Jaehoon Lee, Hyung Gyoo Kang and Yung Chil Hah, Detection of ß-Glucosidase Activity in Polyacrylamide Gels with Esculin as Substrate, Appl. Environ. Microbil., 1994, vol. 80, 4584-4586
[4] Dennis J Mckenna, Kenneth Jones, Kerry Hughes and Virginia M Tyler, Botanical Medicines: The Desk Reference for Major Herbal Supplements, Second Edition, 2011

Chemical Properties

White to nearly white

Uses

Esculin hydrate has been used as a component of sporulation-inducing esculin agar. It has also been used for esculin uptake assay.

Uses

esculoside is utilized in formulations for the treatment of cellulite. es culoside is apparently beneficial for impaired microcirculation.

Uses

esculin is used as a skin protectant in ointments and creams. This is a glucoside compound originally obtained from the leaves and bark of the horse chestnut tree.

Definition

ChEBI: A hydroxycoumarin that is the 6-O-beta-D-glucoside of esculetin.

General Description

Esculin hydrate has vasoprotective and venotonic properties.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

Esculin is a coumarin glycoside that demonstrates antioxidant activitites and protection against chemically-induced carcinogenesis. Esculin is utilized in microbiology for the isolation and identification of Enterococcus (group D streptococci).

Esculin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 404)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Haibo Biotechnology Co., Ltd
+86-02963020060 +86-18629295024 hibo06@xaltbio.com China 1000 58
Henan Fengda Chemical Co., Ltd
+8613613820652 info@fdachem.com China 5085 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21700 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9354 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3424 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58

View Lastest Price from Esculin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Aesculin pictures 2024-03-28 Aesculin
531-75-9
US $100.00 / kg 1kg 10-98% 10000 Changsha Staherb Natural Ingredients Co., Ltd.
Esculin pictures 2024-03-28 Esculin
US $10.00 / kg 1kg 80% 10000 Changsha Staherb Natural Ingredients Co., Ltd.
Esculin pictures 2024-03-26 Esculin
531-75-9
US $5.00-0.20 / KG 1KG 98% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
  • Aesculin pictures
  • Aesculin
    531-75-9
  • US $100.00 / kg
  • 10-98%
  • Changsha Staherb Natural Ingredients Co., Ltd.
  • Esculin pictures
  • Esculin
  • US $10.00 / kg
  • 80%
  • Changsha Staherb Natural Ingredients Co., Ltd.
  • Esculin pictures
  • Esculin
    531-75-9
  • US $5.00-0.20 / KG
  • 98%
  • Henan Fengda Chemical Co., Ltd
BICOLOIN ESCULETIN-6-O-GLUCOSIDE ESCULIN ESCULETIN-6-GLUCOSIDE ESCULOSIDE Esculinsesquimonohydrate 2H-1-Benzopyran-2-one, 6-(beta-D-glucopyranosyloxy)-7-hydroxy- 6,7-DIHYDROXYCOUMARIN-6-O-GLUCOSIDE 6-(beta-d-glucopyranosyloxy)-7-hydroxy-2h-1-benzopyran-2-one 6-(BETA-D-GLUCOPYRANOSYLOXY)-7-HYDROXY-2H-1-BEZOPYRAN-2-ONE 6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one 6,7-Dihydrocoumarin-6-glucoside 6-β-Glucosido-7-hydrox Aesculin;Bicolorin;6,7-Dihydrocoumarin-6-glucoside;6,7-Dihydroxycoumarin 6-glucoside;Enallachrome;Escosyl;Esculetin-6-β-D-glucopyranoside;Esculin;Esculinic acid;Esculoside;6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one;6-β-Glucosido-7-hydrox Esculinic acid ESCULIN, PLANT EXTRACT 10:1 AESCULIN (Esculin Sesquihydrate) EsculinNLT98% 7-hydroxycoumarin-6-yl beta-d-glucopyranoside ESCULIN(ESCULETIN-6-GLUCOSIDE)(P) 7-HYDROXY-6-O-GLUCOSYLCOUMARIN 6-(β-D-Glucopyranosyloxy)-7-hydroxycoumarin ESCULIN extrapure AESCULETIN AESCULETIN-6B-D-GLUCOPYRANOSIDE AESCULETIN-6-BETA-D-GLUCOPYRANOSIDE AESCULIN POLYDROM POLYCHROME 6-(beta-d-glucopyranosyloxy)-7-hydroxy-2h-1-benzopyran-2-on Bicolorin Crataegin Enallachrome Escosyl Esculetin 6-beta-D-glucoside Esculine Polychrom Vitamin C2 vitaminc2 6,7-DIHYDROXYCOUMARIN 6-GLUCOSIDE Esculin,Esculine 6-(b-D-Glucopyranosyloxy)-7-hydroxycoumarin Esculetin 6-b-D-glucoside Esculin hydrate,97% 6-glucoside hydrate F. bangeana DC.p.e 6-glucoside hydrat 7-hydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chroMen-2-one Esculin hydrate, 97% 10GR Aesculin (Esculin) Schillerstoff 2H-1-Benzopyran-2-one,6-(b-D-glucopyranosyloxy)-7-hydroxy- 2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy)-7-hydroxy- 6,7-dihydroxychromen-2-one 6-β-D-glucoside 6,7-dihydroxycoumarin 6-β-D-glucoside 7-hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy- 6-(hydroxymethyl)-2-tetrahydropyranyl]oxy}-2-chromenone Esculetin 6-β-D-glucoside 7-hydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-1-benzopyran-2-one hydrate