Y 134

CAS No.
849662-80-2
Chemical Name:
Y 134
Synonyms
Y 134;Y-134,Y134;[6-HYDROXY-2-(4-HYDROXYPHENYL)BENZO[B]THIEN-3-YL]-[4-[4-(1-METHYLETHYL)-1-PIPERAZINYL]PHENYL]METHANONE;Methanone, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[4-(1-methylethyl)-1-piperazinyl]phenyl]-
CBNumber:
CB82453417
Molecular Formula:
C28H28N2O3S
Molecular Weight:
472.6
MDL Number:
MFCD09970973
MOL File:
849662-80-2.mol
Last updated:2023-09-04 15:51:00

Y 134 Properties

storage temp. Desiccate at RT
solubility Soluble to 100 mM in DMSO and to 100 mM in ethanol
form Powder

Y 134 price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 2676 Y134 ≥98%(HPLC) 849662-80-2 10 $191 2021-12-16 Buy
Tocris 2676 Y134 ≥98%(HPLC) 849662-80-2 50 $751 2021-12-16 Buy
TRC Y120005 Y134 849662-80-2 100mg $1260 2021-12-16 Buy
TRC Y120005 Y134 849662-80-2 10mg $160 2021-12-16 Buy
TRC Y120005 Y134 849662-80-2 50mg $710 2021-12-16 Buy
Product number Packaging Price Buy
2676 10 $191 Buy
2676 50 $751 Buy
Y120005 100mg $1260 Buy
Y120005 10mg $160 Buy
Y120005 50mg $710 Buy

Y 134 Chemical Properties,Uses,Production

Uses

Y 134 is a SERM displaying selectivity for ERα over ERβ.

Definition

ChEBI: [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(4-propan-2-yl-1-piperazinyl)phenyl]methanone is an aromatic ketone.

Biological Activity

Selective estrogen receptor modulator (SERM) that displays selectivity for ER α over ER β (K i values are 0.09 and 11.31 nM respectively) and no cross-reactivity with mineralocorticoid, glucocorticoid, androgen and progesterone receptors. Acts as an agonist in the bone and antagonist in reproductive tissue. Suppresses estrogen-stimulated proliferation of ER-positive human breast cancer MCF-7 and T47D cells.

storage

Desiccate at RT

Y 134 Preparation Products And Raw materials

Raw materials

Preparation Products

Y 134 Suppliers

Global( 24)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9445 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9414 58
ShangHai ChuanQian Chemcial Technique Centre 15869524721 3525679403@qq.com China 3915 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58

Y 134 Spectrum

849662-80-2(Y 134)Related Search:

Y 134 [6-HYDROXY-2-(4-HYDROXYPHENYL)BENZO[B]THIEN-3-YL]-[4-[4-(1-METHYLETHYL)-1-PIPERAZINYL]PHENYL]METHANONE Methanone, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[4-(1-methylethyl)-1-piperazinyl]phenyl]- Y-134,Y134 849662-80-2