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PI-103

PI-103
PI-103 structure
CAS No.
371935-74-9
Chemical Name:
PI-103
Synonyms
PI-103;PI 103;PI 103 HYDROCHLORIDE;PI-103, Free Base, >99%;PI-103HydrochlorideSalt;PI 3-Kinase Inhibitor (PI-103) B-0303;PI-103 - CAS 371935-74-9 - Calbiochem;PI-103, 98%, a potent PI3K/Akt and mTOR inhibitor;3-(4-Morpholinopyrido[3',2':4,5] furo[3,2-d]pyriMidin-2-yl)phenol;3-[4-(4-Morpholinylpyrido[3',2',4,5]furo[3,2-d]pyrimidin-2-yl]phenol;3-[4-Morpholin-4-ylpyrido[3',2':4,5]furo[3,2-d]pyriMidin-2-yl]phenol
CBNumber:
CB82454333
Molecular Formula:
C19H16N4O3.ClH
Formula Weight:
384.821
MOL File:
371935-74-9.mol

PI-103 Properties

Density 
1.409±0.06 g/cm3(Predicted)
storage temp. 
Desiccate at +4°C
form 
White solid
pka
9.06±0.10(Predicted)

PI-103 price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 528100 PI-103 - CAS 371935-74-9 - Calbiochem
A cell-permeable pyridinylfuranopyrimidine compound that acts as a potent and ATP-competitive inhibitor of DNA-PK, PI3-K, and mTOR.
371935-74-9 1mg $130 2019-12-02 Buy
Sigma-Aldrich 528100 PI-103 - CAS 371935-74-9 - Calbiochem
A cell-permeable pyridinylfuranopyrimidine compound that acts as a potent and ATP-competitive inhibitor of DNA-PK, PI3-K, and mTOR.
371935-74-9 5mg $478 2019-12-02 Buy
Cayman Chemical 10009209 PI-103 ≥98% 371935-74-9 1mg $23 2020-06-24 Buy
Cayman Chemical 10009209 PI-103 ≥98% 371935-74-9 5mg $92 2020-06-24 Buy
Cayman Chemical 10009209 PI-103 ≥98% 371935-74-9 10mg $138 2020-06-24 Buy

PI-103 Chemical Properties,Uses,Production

Definition

ChEBI: An organic heterotricyclic compound that is pyrido[3',2':4,5]furo[3,2-d]pyrimidine substituted at positions 2 and 4 by 3-hydroxyphenyl and morpholin-4-yl groups respectively. A dual-kinase inhibitor with anti-cancer properties.

Biological Activity

Inhibitor of DNA-PK, PI 3-kinase (p110 α ) and mTOR (IC 50 values are 2, 8, 20, 26, 48, 83, 88, 150, 850, 920, ~ 1000 and 2300 nM for DNA-PK, p110 α , mTORC1, PI3KC2 β , p110 δ , mTORC2, p110 β , p110 γ , ATR, ATM, PI3KC2 α and hsVPS34 respectively). Inhibits growth of human tumor xenografts in mice in vivo .

PI-103 Preparation Products And Raw materials

Raw materials

Preparation Products


PI-103 Suppliers

Global( 117)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86-571-85586718
+86-571-85864795 sales@capotchem.com China 19929 60
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 24723 60
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30045 58
Biochempartner
0086-13720134139
candy@biochempartner.com CHINA 968 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 linda@hubeijusheng.com CHINA 23045 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 35434 58
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63728 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com CHINA 47486 58
Amadis Chemical Company Limited
0086-571-89925085
0086-571-89925065 sales@amadischem.com China 132149 58
Chuzhou KeMail Chemical Technology Co., Ltd 15000891977 0550-5196001
0550-5196001 wj520wjxby@126.com China 1526 55

View Lastest Price from PI-103 manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-24 PI-103
371935-74-9
US $2.00 / kg 1kg 99% 100kg career henan chemical co

371935-74-9(PI-103)Related Search:


  • Phenol, 3-[4-(4-Morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyriMidin-2-yl]-
  • 3-(4-Morpholinopyrido[3',2':4,5] furo[3,2-d]pyriMidin-2-yl)phenol
  • PI-103, Free Base, >99%
  • PI 3-Kinase Inhibitor (PI-103) B-0303
  • PI-103HydrochlorideSalt
  • 3-[4-(4-Morpholinylpyrido[3',2',4,5]furo[3,2-d]pyrimidin-2-yl]phenol
  • 3-(4-morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol hydrochloride
  • 3-[4-(4-Morpholinylpyrido[3',2',4,5]furo[3,2-d]pyrimidin-2-yl]phenol PI 103
  • PI 103 3-[4-(4-Morpholinylpyrido[3',2',4,5]furo[3,2-d]pyrimidin-2-yl]phenol
  • PI-103;PI 103
  • 3-[4-(4-MORPHOLINYLPYRIDO)[3',2':4,5]FURO[3,2-D]PYRIMIDIN-2-YL]PHENOL HYDROCHLORIDE
  • PI 103 HYDROCHLORIDE
  • 3-[4-Morpholin-4-ylpyrido[3',2':4,5]furo[3,2-d]pyriMidin-2-yl]phenol
  • PI-103, 98%, a potent PI3K/Akt and mTOR inhibitor
  • PI-103 - CAS 371935-74-9 - Calbiochem
  • 371935-74-9
  • C19H16N4O3HCl
  • Inhibitors
  • Akt
  • mTOR
  • PI3K
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