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rac-Lasofoxifene

CAS No.
180915-78-0
Chemical Name:
rac-Lasofoxifene
Synonyms
rac-Lasofoxifene;cis-5,6,7,8-Tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2-naphthalenol;(5R,6S)-rel-5,6,7,8-Tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2-naphthalenol;2-Naphthalenol, 5,6,7,8-tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-, (5R,6S)-rel-
CBNumber:
CB82510332
Molecular Formula:
C28H31NO2
Molecular Weight:
413.55
MDL Number:
MFCD00949977
MOL File:
180915-78-0.mol
Last updated:2023-05-04 17:34:35

rac-Lasofoxifene Properties

Melting point >155°C (dec.)
storage temp. Refrigerator
solubility Chloroform, Methanol
form Solid
color White to Off-White

rac-Lasofoxifene price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC L176490 rac-Lasofoxifene 180915-78-0 1mg $110 2021-12-16 Buy
TRC L176490 rac-Lasofoxifene 180915-78-0 5mg $495 2021-12-16 Buy
Product number Packaging Price Buy
L176490 1mg $110 Buy
L176490 5mg $495 Buy

rac-Lasofoxifene Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

rac-Lasofoxifene is a non-steroidal selective estrogen receptor modulator, used to treat osteoporosis.

Definition

ChEBI: Lasofoxifene is a member of the class of tetralins that is 5,6,7,8-tetrahydronaphthalen-2-ol in which the hydrogens at positions 5 and 6 are replaced by 4-[2-(pyrrolidin-1-yl)ethoxy]phenyl and phenyl groups, respectively (the 5R,6S-stereoisomer). It is a selective estrogen receptor modulator indicated for the prevention and treatment of osteoporosis in post-menopausal women. It has a role as an antineoplastic agent, a cardioprotective agent, an estrogen receptor agonist, an estrogen receptor antagonist and a bone density conservation agent. It is a member of tetralins, an aromatic ether, a member of naphthols and a N-alkylpyrrolidine.

rac-Lasofoxifene Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 9)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 94838 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979 info@tsbiochem.com China 8073 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55717 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
rac-Lasofoxifene (5R,6S)-rel-5,6,7,8-Tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2-naphthalenol cis-5,6,7,8-Tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2-naphthalenol 2-Naphthalenol, 5,6,7,8-tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-, (5R,6S)-rel- 180915-78-0 Aromatics Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Aromatics, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals