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Y27632 (hydrochloride)

Y27632 (hydrochloride)
Y27632 (hydrochloride) structure
CAS No.
129830-38-2
Chemical Name:
Y27632 (hydrochloride)
Synonyms
CS-1919;Y27632 HCl;Y27632 (hydrochloride);Y-27632; Y27632; Y 27632;Y-27632 dihydrochloride, >=98%;Y27632 (hydrochloride) USP/EP/BP;Y-27632, Dihydrochloride Salt, >99%;Y-27632 DIHYDROCHLORIDE;ROCK INHIBITOR;Y-27632 dihydrochloride, 98.5%, a selective ROCK1 (p160ROCK) inhibitor;Y-27632; Y27632; Y 27632;Y 27632 DIHYDROCHLORIDE;Y27632 DIHYDROCHLORIDE
CBNumber:
CB82526054
Molecular Formula:
C14H23Cl2N3O
Formula Weight:
320.25792
MOL File:
129830-38-2.mol

Y27632 (hydrochloride) Properties

Melting point:
258℃
storage temp. 
2-8°C
solubility 
H2O: soluble14mg/mL
form 
powder
color 
white to beige
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P280-P301+P312+P330
Hazard Codes  Xn
Risk Statements  20/21/22
Safety Statements  36
WGK Germany  3
HS Code  29333990

Y27632 (hydrochloride) price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0503 Y-27632 dihydrochloride ≥98% (HPLC) 129830-38-2 1mg $207 2021-12-16 Buy
Sigma-Aldrich Y0503 Y-27632 dihydrochloride ≥98% (HPLC) 129830-38-2 5mg $714 2021-12-16 Buy
TCI Chemical Y0018 Y 27632 Dihydrochloride 129830-38-2 50MG $479 2021-12-16 Buy
TCI Chemical Y0018 Y 27632 Dihydrochloride 129830-38-2 10MG $160 2021-12-16 Buy
Cayman Chemical 10005583 Y-27632 (hydrochloride) ≥98% 129830-38-2 5mg $113 2021-12-16 Buy

Y27632 (hydrochloride) Chemical Properties,Uses,Production

Uses

A cell permeable inhibitor of ROCK-1 and ROCK-2

Uses

Y-27632 dihydrochloride has been used:
  • as a medium supplement in pancreatic ductal adenocarcinoma organoid culture
  • in the inhibition of Ras homolog gene family (Rho) kinase in mouse embryonic stem cells
  • in the inhibition of Rho-associated protein kinase (ROCK) in human embryonic stem cells and human induced pluripotent stem cells (iPSCs)

General Description

Y-27632 dihydrochloride is an effective bronchodilator and improves lung resistance (RL) induced by antigen and acetylcholine. Y-27632 controls neutrophil migration and lung edema and may be a potential drug for treating acute lung injury.

Biochem/physiol Actions

Y-27632 is highly potent, cell-permeable, selective ROCK (Rho-associated coiled coil forming protein serine/threonine kinase) inhibitor. Ki = 140 nM for p160ROCK. Y-27632 also inhibits ROCK-II with equal potency. The inhibition is competitive with respect to ATP.

Y27632 (hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products


Y27632 (hydrochloride) Suppliers

Global( 126)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Biochempartner
0086-13720134139
candy@biochempartner.com CHINA 968 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com China 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 9150 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 26782 60
Shandong chuangyingchemical Co., Ltd.
18853181302
sale@chuangyingchem.com CHINA 5917 58
BOC Sciences
1-631-485-4226
1-631-614-7828 inquiry@bocsci.com United States 19752 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com China 47498 58
Target Molecule Corp
18019718960 781-999-5354
marketing@targetmol.com United States 19231 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
13588875226 86-571-88216897、88216896
86-571-88216895 sales@hzclap.com CHINA 6469 58

View Lastest Price from Y27632 (hydrochloride) manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-07-02 Cabergoline
81409-90-7
US $3090.00 / g/Bag 1g/Bag 99%+ HPLC Monthly supply of 100KG Zhuozhou Wenxi import and Export Co., Ltd
2021-01-06 Y27632 (hydrochloride)
129830-38-2
US $3.07 / KG 1KG 98% 1000KG Career Henan Chemica Co

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