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(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride

(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride structure

CAS No.: 1204818-19-8

Chemical Name:: (R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride

Synonyms: Sitagliptin-2;Sitalettinic acid;Sitagliptin Impurity 17;Sitagliptin Impurity 2 HCl;Sitagliptin Impurity 4 HCl;Sitagliptin Impurity 13 HCl;Sitagliptin Impurity 25 HCl;Sitagliptin Acid (USP IMP A);Sitagliptin Acid Impurity HCl;Sitagliptin FP Impurity E Hydrochloride

CBNumber:: CB82550778

Molecular Formula:: C10H11ClF3NO2

Molecular Weight:: 269.6480496

MDL Number:: MFCD06659146

MOL File:: 1204818-19-8.mol

Last updated:2023-05-15 10:44:00

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(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride Properties

Melting point	218-220℃
storage temp.	Inert atmosphere,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
color	White to Off-White
Sensitive	Air Sensitive
Stability	Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

NFPA 704

	0
2		0

(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	A630750	(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoicAcidHydrochloride	1204818-19-8	250mg	$145	2021-12-16	Buy
AK Scientific	B604	(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoicacidhydrochloride	1204818-19-8	25mg	$49	2021-12-16	Buy
American Custom Chemicals Corporation	AAA0010959	(R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOIC ACID HYDROCHLORIDE 95.00%	1204818-19-8	5MG	$501.28	2021-12-16	Buy
American Custom Chemicals Corporation	AAA0010959	(R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOIC ACID HYDROCHLORIDE 95.00%	1204818-19-8	250MG	$776	2021-12-16	Buy
Alichem	1204818198	(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoicacidhydrochloride	1204818-19-8	5g	$795.96	2021-12-16	Buy

Product number	Packaging	Price	Buy
A630750	250mg	$145	Buy
B604	25mg	$49	Buy
AAA0010959	5MG	$501.28	Buy
AAA0010959	250MG	$776	Buy
1204818198	5g	$795.96	Buy

(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride Chemical Properties,Uses,Production

Uses

(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic Acid Hydrochloride is an intermediate in the synthesis of the new antidiabetic drug Sitagliptine (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor.

(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride synthesis

Synthesis of (R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride from Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid

(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride Preparation Products And Raw materials

Raw materials

(R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid Sitagliptin Impurity 2,2-DiMethyl-5-[(2,4,5-trifluorophenyl)acetyl]-1,3-dioxane-4,6-dione

ethyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate (R)-3-Amino-4-(2,4,5-trifluorophenyl)butyric acid (R)-Ethyl 2,4,5-trifluoro-b-homophenylalaninateHCl 1-Bromo-2,4,5-trifluorobenzene 2,4,5-Trifluorophenylacetic acid

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Preparation Products

(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride Suppliers

Global( 69)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Allfluoro pharmaceutical co. ltd.	021-26137118 +8615821363818	sales@allfluoro.com	China	5791	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3149	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19915	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12382	58
Zhengzhou Anhuida Chemical Co., Ltd	+8615903659408	admin@ahdchem.com	China	298	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58

Supplier	Advantage
Hubei Jusheng Technology Co.,Ltd.	58
BOC Sciences	58
Allfluoro pharmaceutical co. ltd.	58
Career Henan Chemica Co	58
Hangzhou Huarong Pharm Co., Ltd.	58
Nextpeptide Inc	58
sgtlifesciences pvt ltd	58
Zhengzhou Anhuida Chemical Co., Ltd	58
LEAPCHEM CO., LTD.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58

1204818-19-8((R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride)Related Search:

Sitagliptin Impurity 28 Sitagliptin Impurity 46 Sitagliptin Impurity 77 Sitagliptin impurity 5 Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate

ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate 2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE Sitagliptin Impurity 34 2,4,5-TRIFLUOROBENZYL CHLORIDE (R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate

Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,Methylester,(bR)- Sitagliptin Sitagliptin Impurity 14 Sitagliptin Defuoro IMpurity 5 Sitagliptin DeaMino IMpurity 1

(S)-Sitagliptin Phosphate 2,2,2-TRIFLUORO-N'-(TRIFLUOROACETYL)ACETOHYDRAZIDE (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione

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(R)-b-Amino-2,4,5-trifluoro-benzenebutanoic acid HCl Sitagliptin Impurity 17 Sitagliptin Acid Impurity HCl Sitagliptin-2 Sitagliptin impurity 37/(R)-3-Amino-4-(2,4,5-trifluorophenyl)butyric acid hydrochloride (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid,hydrochloride (R)-3-amino-4-phenyl(2,4,5-trifluorophenyl)butanoic acid hydrochloride (3R)-3-amino -4-(2, 4-difluorophenyl)-1-[3-(trifluoromethyl)butyl]-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]butan-1-one Sitagliptin FP Impurity E Hydrochloride (R)-b-Amino-2,4,5-trifluoro-benzenebutanoic acid hydrochloride Sitagliptin Impurity 25 HCl Sitalettinic acid Sitagliptin Acid (USP IMP A) (βR)-β-Amino-2,4,5-trifluorobenzenebutanoic Acid Hydrochloride Sitagliptin Impurity 2 HCl Sitagliptin Impurity 13 HCl Sitagliptin Impurity 4 HCl Sitagliptin FP Impurity E (Sitagliptin Phosphate Monohydrate Acid Impurity) 1204818-19-8