ChemicalBook >> CAS DataBase List >>CID 5951923
CID 5951923
- CAS No.
- 749872-43-3
- Chemical Name:
- CID 5951923
- Synonyms
- AC1NZ6UQ;CID 5951923;KLF5 Inhibitor, CID 5951923;KLF5 Inhibitor, CID 5951923 - CAS 749872-43-3 - Calbiochem;[2-[(1,1-Dioxothiolan-3-yl)-methylamino]-2-oxoethyl] (E)-3-(3-nitrophenyl)prop-2-enoate;2-((1,1-Dioxidotetrahydrothiophen-3-yl)(methyl)amino)-2-oxoethyl 3-(3-nitrophenyl)acrylate;3-(3-Nitro-phenyl)-acrylic acid [(1,1-dioxo-tetrahydro-1l6-thiophen-3-yl)-methyl-carbamoyl]-me;2-[Methyl(tetrahydro-1,1-dioxido-3-thienyl)amino]-2-oxoethyl (E)-3-(3-nitrophenyl)prop-2-enoate;3-(3-Nitrophenyl)-2-propenoic Acid 2-[Methyl(tetrahydro-1,1-dioxido-3-thienyl)aMino]-2-oxoethyl Ester;3-(3-Nitro-phenyl)-acrylic acid [(1,1-dioxo-tetrahydro-1l6-thiophen-3-yl)-methyl-carbamoyl]-methyl ester
- CBNumber:
- CB82574686
- Molecular Formula:
- C16H18N2O7S
- Molecular Weight:
- 382.39
- MDL Number:
- MFCD04796932
- MOL File:
- 749872-43-3.mol
- MSDS File:
- SDS
Last updated:2023-09-04 15:51:00
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
WGK Germany | 3 |
CID 5951923 price More Price(23)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 422625 | KLF5 Inhibitor, CID 5951923 | 749872-43-3 | 10mg | $172 | 2024-03-01 | Buy |
Sigma-Aldrich | SML0375 | CID 5951923 ≥98% (HPLC) | 749872-43-3 | 5mg | $113 | 2022-05-15 | Buy |
Cayman Chemical | 21649 | CID 5951923 ≥98% | 749872-43-3 | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 21649 | CID 5951923 ≥98% | 749872-43-3 | 5mg | $109 | 2024-03-01 | Buy |
Cayman Chemical | 21649 | CID 5951923 ≥98% | 749872-43-3 | 10mg | $139 | 2024-03-01 | Buy |
CID 5951923 Chemical Properties,Uses,Production
Uses
This compound acts as a KLF-5 expression inhibitor. which in turn reduces proliferation cell rates in colorectal cancer cells in humans.
General Description
A cell-permeable phenylpropenoate compound that inhibits the proliferation of colon cancer cell lines exhibiting high levels of KLF5 (IC50 = 1.6 μM in DLD-1 cells). Downregulates the expression of early growth response protein 1 (EGR1), which modulates KLF5 expression at transcription level. Shown to activate the EGFR/ERK pathway by stimulating phosphorylation of EGFR-Tyr1068 and ERK1/2-Thr202/Tyr204. Also, up-regulates the phosphorylation of p38 MAPK-Thr180/Tyr182.
CID 5951923 Preparation Products And Raw materials
Raw materials
Preparation Products
CID 5951923 Suppliers
Global( 57)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8072 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
Pharmacodia (Beijing) Co.,Ltd | +86-400-851-9921 | sales@pharmacodia.com | China | 2317 | 55 |
CID 5951923
3-(3-Nitrophenyl)-2-propenoic Acid 2-[Methyl(tetrahydro-1,1-dioxido-3-thienyl)aMino]-2-oxoethyl Ester
[2-[(1,1-Dioxothiolan-3-yl)-methylamino]-2-oxoethyl] (E)-3-(3-nitrophenyl)prop-2-enoate
AC1NZ6UQ
3-(3-Nitro-phenyl)-acrylic acid [(1,1-dioxo-tetrahydro-1l6-thiophen-3-yl)-methyl-carbamoyl]-me
KLF5 Inhibitor, CID 5951923
3-(3-Nitro-phenyl)-acrylic acid [(1,1-dioxo-tetrahydro-1l6-thiophen-3-yl)-methyl-carbamoyl]-methyl ester
KLF5 Inhibitor, CID 5951923 - CAS 749872-43-3 - Calbiochem
2-[Methyl(tetrahydro-1,1-dioxido-3-thienyl)amino]-2-oxoethyl (E)-3-(3-nitrophenyl)prop-2-enoate
2-((1,1-Dioxidotetrahydrothiophen-3-yl)(methyl)amino)-2-oxoethyl 3-(3-nitrophenyl)acrylate
Krüppel-like factor,CID-5951923,CID5951923,KLF5,inhibit,cancer,factor,KLF,transcription,Inhibitor,Krüppel-like,CID 5951923
2-Propenoic acid, 3-(3-nitrophenyl)-, 2-[methyl(tetrahydro-1,1-dioxido-3-thienyl)amino]-2-oxoethyl ester
749872-43-3
Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals