Uric Acid Assay Kit

Description

Uric acid (urate) is the end product of human purine metabolism and is mainly excreted in urine. Many factors, including genetic components and acquired factors, such as obesity and alcohol consumption, influence serum uric acid concentrations. Hyperuricemia induces or facilitates gout, kidney stones, metabolic syndrome, hypertension, and renal and cardiovascular disease, while exercise-induced acute renal failure is a significant complication of renal hypouricemia. Cayman’s Uric Acid Assay provides a fluorescence-based method for detecting uric acid in serum, plasma, and urine.

Uses

Uric Acid Assay Kit has been used

• to determine the uric acid content in human adipose-derived stem cell culture supernatant
• to measure serum uric acid level in order to analyse kidney function in rat models
• to determine the uric acid concentration in serum and to study the e antiinflammatory effects of sunflower head ethanol extract in rats
• in quantitative analysis of uric acid degradation

General Description

In humans and primates, uric acid is the end product of purine metabolism. It is produced by the oxidation of xanthine and hypoxanthine by xanthine oxidase and excreted in urine. High serum levels of uric acid, hyperuricemia, are associated with insulin resistance, cardiovascular disease, and gout. The mechanisms leading to hyperuricemia are typically either increased uric acid production or decreased urine excretion. Increased serum uric acid may be a marker of renal disease.