ChemicalBook >> CAS DataBase List >>4-Chloro-3-nitroaniline

4-Chloro-3-nitroaniline

CAS No.
635-22-3
Chemical Name:
4-Chloro-3-nitroaniline
Synonyms
4-Chlor-3-nitroanilin;3-NITRO-4-CHLOROANILINE;4-CHLORO-3-NITROANILINE;4-chloro-3-nitro-anilin;Aniline, 4-chloro-3-nitro-;4-Chloro-3-nitrobenzenamine;4-chloro-3-nitro-benzenamin;4-Chloro-3-nitroaniline,97%;4-Chloro-3-nitroaniline >5-Amino-2-chloronitrobenzene
CBNumber:
CB8264060
Molecular Formula:
C6H5ClN2O2
Molecular Weight:
172.57
MDL Number:
MFCD00007844
MOL File:
635-22-3.mol
MSDS File:
SDS
Last updated:2024-01-02 10:32:02

4-Chloro-3-nitroaniline Properties

Melting point 99-101 °C (lit.)
Boiling point 200°C (rough estimate)
Density 1.5610 (rough estimate)
refractive index 1.5870 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka 1.87±0.10(Predicted)
form powder to crystal
color White to Yellow to Orange
BRN 1309394
InChI InChI=1S/C6H5ClN2O2/c7-5-2-1-4(8)3-6(5)9(10)11/h1-3H,8H2
InChIKey FOHHWGVAOVDVLP-UHFFFAOYSA-N
SMILES C1(N)=CC=C(Cl)C([N+]([O-])=O)=C1
CAS DataBase Reference 635-22-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII B13U77ZL3A
NIST Chemistry Reference Benzenamine, 4-chloro-3-nitro-(635-22-3)
EPA Substance Registry System 4-Chloro-3-nitroaniline (635-22-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08,GHS09,GHS07
Signal word  Danger
Hazard statements  H300+H310+H330-H315-H319-H300-H310-H330-H373-H411
Precautionary statements  P301+P310a-P304+P340-P320-P330-P501a-P260-P264-P273-P280-P284-P302+P350-P262-P270-P271-P301+P310+P330-P302+P352+P310+P361+P364-P304+P340+P310-P305+P351+P338+P337+P313-P314-P391-P403+P233-P405-P501
Hazard Codes  T+,N,T
Risk Statements  26/27/28-33-51/53
Safety Statements  28-36/37-45-61-28A
RIDADR  UN 2237 6.1/PG 3
WGK Germany  3
RTECS  BX1750000
Hazard Note  Very Toxic
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29214210
NFPA 704
0
4 0

4-Chloro-3-nitroaniline price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C1138 4-Chloro-3-nitroaniline >99.0%(GC)(T) 635-22-3 25g $20 2024-03-01 Buy
TCI Chemical C1138 4-Chloro-3-nitroaniline >99.0%(GC)(T) 635-22-3 500g $116 2021-12-16 Buy
American Custom Chemicals Corporation HCH0023453 4-CHLORO-3-NITROANILINE 95.00% 635-22-3 1G $128.1 2021-12-16 Buy
Matrix Scientific 081157 4-Chloro-3-nitroaniline 97% 635-22-3 50g $135 2021-12-16 Buy
Biosynth Carbosynth FC170383 4-Chloro-3-nitroaniline 635-22-3 100g $150 2021-12-16 Buy
Product number Packaging Price Buy
C1138 25g $20 Buy
C1138 500g $116 Buy
HCH0023453 1G $128.1 Buy
081157 50g $135 Buy
FC170383 100g $150 Buy

4-Chloro-3-nitroaniline Chemical Properties,Uses,Production

Chemical Properties

ochre powder

Uses

Intermediate in the manufacture of azo dyes, pharmaceuticals, and other organic compounds.

Application

Commercial 4-chloro-3-nitroaniline could be used as a starting material for 3-azido-4-chlorophenylisothiocyanate through a 5-step synthesis. In order to research the impact of the strain on the metabolite profile of plasma samples in rats, 45 mg/kg bw/day 4-chloro-3-nitroaniline (4C3N) was evaluated for 4 weeks. 4C3N administration led to extravascular hemolytic anemia with a few metabolome changes, which were strain-dependent [1-2].

Hazard

Toxic by ingestion and inhalation.

Safety Profile

Poison by ingestion and intraperitoneal routes. Experimental reproductive effects. Skin and eye irritant. When heated to decomposition it emits toxic fumes of NOx and Cl-.

References

[1] H. Lamotte. “Synthesis of N‐(3‐azido‐4‐chlorophenyl)‐N′‐[3H‐methyl] thiourea, an efficient photoaffinity probe for the urea carrier.” Journal of Labelled Compounds and Radiopharmaceuticals 42 1 (1994): 289–295.
[2] O’Donoghue, John L. “Subchronic oral toxicology of 4-chloro-3-nitroaniline in the rat.” Fundamental and Applied Toxicology 6 3 (1986): Pages 551-558.

Global( 150)Suppliers
Supplier Tel Email Country ProdList Advantage
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21700 55
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-81138252 +86-18789408387 1057@dideu.com China 3979 58
Fuxin Pharmaceutical
+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10297 58
Antai Fine Chemical Technology Co.,Limited
18503026267 info@antaichem.com CHINA 9641 58

Related articles

View Lastest Price from 4-Chloro-3-nitroaniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Chloro-3-nitroaniline  pictures 2022-07-30 4-Chloro-3-nitroaniline
635-22-3
US $1.10 / g 1g 99.00% 100 Tons Min Dideu Industries Group Limited
4-Chloro-3-nitroaniline pictures 2020-01-10 4-Chloro-3-nitroaniline
635-22-3
US $1.00 / g 1g 99.0% 100kg Career Henan Chemical Co
4-Chloro-3-nitroaniline  pictures 2019-12-31 4-Chloro-3-nitroaniline
635-22-3
US $1.00 / KG 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd
4-chloro-3-nitro-benzenamin Aniline, 4-chloro-3-nitro- benzenamine,-chloro-3-nitro- 5-Amino-2-chloronitrobenzene 4-AMINO-1-CHLORO-2-NITROBENZENE 4-Chloro-3-nitrobenzenamine 4-CHLORO-3-NITROANILINE 3-NITRO-4-CHLOROANILINE 1-AMINO-4-CHLORO-3-NITROBENZENE 4-Chloro-3-Nitroaniline 3-Nitro-4-Chloroaniline 4-Chlor-3-nitroanilin 4-Chloro-3-nitroaniline,97% 4-CHLORO-3-NITROANILINE 99+% 1-Amino-3-nitro-4-Chlorobenzene 4-chloro-3-nitro-anilin 4-Chloro-3-nitroaniline > Benzenamine, 4-chloro-3-nitro- 4-Chloro-3-nitroaniline ISO 9001:2015 REACH 635-22-3 C6H5N2ClO2 Amines Building Blocks C2 to C6 Organic Building Blocks Nitrogen Compounds Amines Building Blocks C6 Chemical Synthesis Nitrogen Compounds Organic Building Blocks Aromatics Compounds Intermediates of Dyes and Pigments