8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt
![8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt Structure](CAS/20150408/GIF/276695-22-8.gif)
- CAS No.
- 276695-22-8
- Chemical Name:
- 8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt
- Synonyms
- (Rac)-WAY-161503 (hydrochloride);8,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one hydrochloride;8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt
- CBNumber:
- CB82662976
- Molecular Formula:
- C11H12Cl3N3O
- Molecular Weight:
- 308.59148
- MDL Number:
- MFCD06411596
- MOL File:
- 276695-22-8.mol
| Product description | Number | Pack Size | Price |
| WAY 161503 hydrochloride ≥98% (HPLC) | W0270 | 5mg | $118.75 |
| WAY 161503 hydrochloride ≥98% (HPLC) | W0270 | 25mg | $435 |
| WAY 161503 hydrochloride | W498705 | 10mg | $115 |
| WAY 161503 hydrochloride | B6859 | 10mg | $234 |
| WAY 161503 hydrochloride | B6859 | 50mg | $975 |
8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W0270 | WAY 161503 hydrochloride ≥98% (HPLC) | 276695-22-8 | 5mg | $118.75 | 2025-07-31 | Buy |
| Sigma-Aldrich | W0270 | WAY 161503 hydrochloride ≥98% (HPLC) | 276695-22-8 | 25mg | $435 | 2022-05-15 | Buy |
| TRC | W498705 | WAY 161503 hydrochloride | 276695-22-8 | 10mg | $115 | 2021-12-16 | Buy |
| ApexBio Technology | B6859 | WAY 161503 hydrochloride | 276695-22-8 | 10mg | $234 | 2021-12-16 | Buy |
| ApexBio Technology | B6859 | WAY 161503 hydrochloride | 276695-22-8 | 50mg | $975 | 2021-12-16 | Buy |
8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt Chemical Properties,Uses,Production
Uses
WAY 161503 Hydrochloride is a potent serotonin 5-HT2C receptor agonist with antiobesity effects. It is the salt analogue of WAY 161503 (D437235).
Biological Activity
The 5-HT2C receptors have been implicated in conditions including obesity, anxiety, depression, OCD, schizophrenia, migraine, nociception and erectile dysfunction.
in vivo
(Rac)-WAY-161503 (3-30 mg/kg; i.p.; male C57BL/6J mice) hydrochloride dose-dependently decreases locomotor activity, an effect that is blocked by the 5-HT2C/2B antagonist SER-082[1].
| Animal Model: | Male C57BL/6J mice with hallucinogen 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)[1] |
| Dosage: | 3 mg/kg, 10 mg/kg, 30 mg/kg |
| Administration: | Intraperitoneal injection (i.p.) |
| Result: | Antagonized the PGE2-mediated inhibition of LPS-induced TNF-α release from rat whole blood culture, in a dose-dependent way. |
IC 50
5-HT2C Receptor: 4 nM (Ki); 5-HT2C Receptor: 12 nM (EC50)
storage
Desiccate at RT
8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt Preparation Products And Raw materials
Raw materials
Preparation Products
8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32435 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3135 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19962 | 58 |
| Tianjin Derchemist Science & Technology Co., Ltd. | 22-58627059 13920586291 | zdcomcon@126.com | China | 3829 | 50 |
| Jiaxing Novartis Chemical Co., Ltd. | 18957373295 | China | 1580 | 58 | |
| Cool Pharm, Ltd | 021-58581007 18019463053 | sales@coolpharm.com | China | 12884 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44918 | 58 |
| Nantong Hi-Future Biotechnology Co., Ltd | 18051384581 | sales@chemhifuture.com | China | 2997 | 58 |
View Lastest Price from 8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-10-27 | WAY 161503 hydrochloride
276695-22-8
|
US $2500.00-1520.00 / mg | 10g | TargetMol Chemicals Inc. |
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- WAY 161503 hydrochloride
276695-22-8
- US $2500.00-1520.00 / mg
- TargetMol Chemicals Inc.
