Thiazolidine-4-carboxylic acid
- CAS No.
- 444-27-9
- Chemical Name:
- Thiazolidine-4-carboxylic acid
- Synonyms
- TIMONACIC;THIOPROLINE;Timonacic Acid;t-4ca;Detoxepa;norgamem;nsc25855;Hepaldine;usafa-3701;AURORA 619
- CBNumber:
- CB8271143
- Molecular Formula:
- C4H7NO2S
- Molecular Weight:
- 133.17
- MDL Number:
- MFCD00128958
- MOL File:
- 444-27-9.mol
- MSDS File:
- SDS
| Melting point | 196.5°C |
|---|---|
| Boiling point | 350.3±37.0 °C(Predicted) |
| Density | 1.226 (estimate) |
| refractive index | 1.5480 (estimate) |
| storage temp. | Room Temperature |
| solubility | DMSO (Slightly), Water (Slightly) |
| form | solid |
| pka | 2.09±0.20(Predicted) |
| Water Solubility | 29.3g/L(21 ºC) |
| CAS DataBase Reference | 444-27-9(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | E5913T3IBL |
| NCI Drug Dictionary | timonacic |
| EPA Substance Registry System | 4-Thiazolidinecarboxylic acid (444-27-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H312+H332-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P310+P330-P302+P352+P312-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P403+P233-P405-P501 |
| RIDADR | 2811 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
Thiazolidine-4-carboxylic acid price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AK Scientific | I627 | 1,3-Thiazolidine-4-carboxylicacid | 444-27-9 | 100mg | $81 | 2021-12-16 | Buy |
| AK Scientific | J55101 | 1,3-Thiazolidine-4-carboxylicacid | 444-27-9 | 100mg | $60 | 2021-12-16 | Buy |
| Matrix Scientific | 174045 | 1,3-Thiazolidine-4-carboxylic acid | 444-27-9 | 1g | $432 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0015821 | 4-THIAZOLIDINECARBOXYLIC ACID 95.00% | 444-27-9 | 0.5G | $605 | 2021-12-16 | Buy |
| Matrix Scientific | 174045 | 1,3-Thiazolidine-4-carboxylic acid | 444-27-9 | 5g | $1206 | 2021-12-16 | Buy |
Thiazolidine-4-carboxylic acid Chemical Properties,Uses,Production
Originator
Hepaldine,Riker,France,1964
Uses
Timonacic is a derivative of Proline (P756050), a cyclic nonessential amino acid. Timonacic is a research molecule of interest with potential antineoplastic activities by acting on the cell membrane of tumour cells and causing reverse transformation to normal cells.
Uses
hepatoprotectant
Definition
ChEBI: A sulfur-containing amino acid that is proline in which the methylene group at position 4 is replaced by a sulfur atom.
Manufacturing Process
Cysteine is first dissolved in distilled water which has been freed of oxygen by boiling. Formaldehyde of 30% (w/v) concentration is added while stirring and the temperature of the mixture rises, while the thiazolidine carboxylic acid begins crystallizing. The stirring is continued for 2 hours after which ethyl alcohol of 95% (w/v) concentration is added to induce further crystallization. The mixture is left to stand for 24 hours at 4°C. The mixture is then filtered with retention of a crude product, which is purified by recrystallization from boiling distilled water. The crystals are then dried at about 40°C. The free acid is then converted to the sodium salt with NaOH.
Therapeutic Function
Hepatoprotectant, Choleretic
Thiazolidine-4-carboxylic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12382 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
View Lastest Price from Thiazolidine-4-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | Thiazolidine-4-carboxylic acid
444-27-9
|
US $1.00 / KG | 1G | 98% | 100KG | Career Henan Chemical Co |
-
- Thiazolidine-4-carboxylic acid
444-27-9
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
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