ChemicalBook >> CAS DataBase List >>I-CBP112
I-CBP112
- CAS No.
- 1640282-31-0
- Chemical Name:
- I-CBP112
- Synonyms
- CS-2420;I-CBP112;I-CBP112, >98%;I-CBP112 hydrochloride;I-CBP112, 1640282-31-0;I-CBP112; I-CBP-112; I-CBP 112;I-CBP112,Inhibitor,HATs,I CBP112,inhibit,I-CBP-112,HAT,ICBP112,Epigenetic Reader Domain,Histone Acetyltransferase;1-[7-(3,4-dimethoxyphenyl)-9-[[(3S)-1-methyl-3-piperidyl]methoxy]-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]propan-1-one;1-Propanone, 1-[7-(3,4-dimethoxyphenyl)-2,3-dihydro-9-[[(3S)-1-methyl-3-piperidinyl]methoxy]-1,4-benzoxazepin-4(5H)-yl]-;1-[7-(3,4-Dimethoxyphenyl)-9-[[(3S)-1-methylpiperidin-3-yl]methoxy]-2,3,4,5-tetrahydro-1,4-benzoxazepin-4-yl]propan-1-one
- CBNumber:
- CB82714666
- Molecular Formula:
- C27H36N2O5
- Molecular Weight:
- 468.59
- MDL Number:
- MFCD26792587
- MOL File:
- 1640282-31-0.mol
Last updated:2023-06-30 15:45:59
| Boiling point | 623.5±55.0 °C(Predicted) |
|---|---|
| Density | 1.129±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility |
DMSO:63.0(Max Conc. mg/mL);134.44(Max Conc. mM) Ethanol:94.0(Max Conc. mg/mL);200.6(Max Conc. mM) Water:94.0(Max Conc. mg/mL);200.6(Max Conc. mM) |
| pka | 9.07±0.10(Predicted) |
| form | powder |
| color | white to beige |
I-CBP112 price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1134 | I-CBP112 ≥98% (HPLC) | 1640282-31-0 | 5mg | $197 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1134 | I-CBP112 ≥98% (HPLC) | 1640282-31-0 | 25mg | $230.8 | 2024-03-01 | Buy |
| Tocris | 4891 | I-CBP112 ≥98%(HPLC) | 1640282-31-0 | 10 | $289 | 2021-12-16 | Buy |
| Tocris | 4891 | I-CBP112 ≥98%(HPLC) | 1640282-31-0 | 50 | $1195 | 2021-12-16 | Buy |
| TRC | I163883 | I-CBP112 | 1640282-31-0 | 2.5mg | $360 | 2021-12-16 | Buy |
I-CBP112 Chemical Properties,Uses,Production
Uses
I-CBP112 has been used in cell culture and sample preparation, to verify the acetylation of VPS34 (vacuolar protein sorting 34), by p300 at K29, K771 and K781 and to diminish synergistic gene expression.
Biochem/physiol Actions
I-CBP112 is a selective inhibitor of the bromodomain-containing transcription factors CREBBP (CBP) and EP300 (IC50 = 0.142 and 0.625 μM, respectively). I-CBP112 has little activity against other bromodomains at concentrations up to 1 mM. For full characterization details, please see I-CBP112 on the Structural Genomics Consortium (SGC) website.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
storage
+4°C
I-CBP112 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 71)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
View Lastest Price from I-CBP112 manufacturers
I-CBP112
1-[7-(3,4-Dimethoxyphenyl)-9-[[(3S)-1-methylpiperidin-3-yl]methoxy]-2,3,4,5-tetrahydro-1,4-benzoxazepin-4-yl]propan-1-one
I-CBP112, 1640282-31-0
I-CBP112 hydrochloride
I-CBP112, >98%
I-CBP112; I-CBP-112; I-CBP 112
CS-2420
1-Propanone, 1-[7-(3,4-dimethoxyphenyl)-2,3-dihydro-9-[[(3S)-1-methyl-3-piperidinyl]methoxy]-1,4-benzoxazepin-4(5H)-yl]-
I-CBP112,Inhibitor,HATs,I CBP112,inhibit,I-CBP-112,HAT,ICBP112,Epigenetic Reader Domain,Histone Acetyltransferase
1-[7-(3,4-dimethoxyphenyl)-9-[[(3S)-1-methyl-3-piperidyl]methoxy]-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]propan-1-one
1640282-31-0