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NIBR189

CAS No.
1599432-08-2
Chemical Name:
NIBR189
Synonyms
NIBR189;CS-1583;NIBR-189; NIBR 189;(E)-3-(4-bromophenyl)-1-(4-(4-methoxybenzoyl)piperazin-1-yl)prop-2-en-1-one;(2E)-3-(4-Bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-2-propen-1-one;(2E)-3-(4-Bromophenyl)-1-[4-4-methoxybenzoyl)-1-piperazinyl]-2-propene-1-one;2-Propen-1-one, 3-(4-bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-, (2E)-;Inhibitor,mice,small molecule,NIBR 189,autoimmune diseases,autoimmune,EBI2/GPR183,NIBR189,U937,NIBR-189,G protein,inhibit,migration
CBNumber:
CB82715658
Molecular Formula:
C21H21BrN2O3
Molecular Weight:
429.31
MDL Number:
MFCD13304236
MOL File:
1599432-08-2.mol
Last updated:2023-06-30 15:45:59

NIBR189 Properties

Boiling point 639.7±55.0 °C(Predicted)
Density 1.403±0.06 g/cm3(Predicted)
storage temp. Desiccate at -20°C
solubility ≥42.9 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form solid
pka -0.86±0.70(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
NFPA 704
0
2 0

NIBR189 price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 18792 NIBR189 ≥95% 1599432-08-2 1mg $44 2024-03-01 Buy
Cayman Chemical 18792 NIBR189 ≥95% 1599432-08-2 5mg $109 2024-03-01 Buy
Cayman Chemical 18792 NIBR189 ≥95% 1599432-08-2 10mg $172 2024-03-01 Buy
Tocris 5203 NIBR189 ≥99%(HPLC) 1599432-08-2 10 $193 2021-12-16 Buy
Tocris 5203 NIBR189 ≥99%(HPLC) 1599432-08-2 50 $789 2021-12-16 Buy
Product number Packaging Price Buy
18792 1mg $44 Buy
18792 5mg $109 Buy
18792 10mg $172 Buy
5203 10 $193 Buy
5203 50 $789 Buy

NIBR189 Chemical Properties,Uses,Production

Uses

(2E)-3-(4-Bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-2-propen-1-one recently known as NIBR 189, is a selective Epstein-barr virus-induced gene 2 (EBI-2) receptor antagonist, resulting in a modulation of immune responses related to auto-immune diseases.

Biological Activity

nibr189 is a small molecule antagonist of the epstein-barr virus-induced gene 2 (ebi2; gpr183) receptor with ic50 of 16 nm(binding) and 11 nm (functional).

storage

Store at +4°C

NIBR189 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 77)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
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BOC Sciences
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Alchem Pharmtech,Inc.
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Career Henan Chemica Co
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HANGZHOU CLAP TECHNOLOGY CO.,LTD
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Zhejiang J&C Biological Technology Co.,Limited
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InvivoChem
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Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581 sales@chemhifuture.com China 3136 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11681 58

NIBR189 Spectrum

NIBR189 (E)-3-(4-bromophenyl)-1-(4-(4-methoxybenzoyl)piperazin-1-yl)prop-2-en-1-one (2E)-3-(4-Bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-2-propen-1-one 2-Propen-1-one, 3-(4-bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-, (2E)- (2E)-3-(4-Bromophenyl)-1-[4-4-methoxybenzoyl)-1-piperazinyl]-2-propene-1-one NIBR-189; NIBR 189 CS-1583 Inhibitor,mice,small molecule,NIBR 189,autoimmune diseases,autoimmune,EBI2/GPR183,NIBR189,U937,NIBR-189,G protein,inhibit,migration 1599432-08-2 api