ChemicalBook >> CAS DataBase List >>LCZ696 InteMediate
LCZ696 InteMediate
- CAS No.
- 1426129-50-1
- Chemical Name:
- LCZ696 InteMediate
- Synonyms
- (R)-tert-butyl 1-(biphenyl-4-yl)-3-hydroxypropan-2-ylcarbamate;150kg;EOS-61581;LCZ696interN-3;Shakubiqu 50-1;LCZ696 InteMediate;(1-([1,1'-biphenyL;LCZ696 InteMediate I;(R)-tert-butyl (1-([1;)-3-hydroxypropan-2-yL
- CBNumber:
- CB82723677
- Molecular Formula:
- C20H25NO3
- Molecular Weight:
- 327.42
- MDL Number:
- MFCD28359221
- MOL File:
- 1426129-50-1.mol
Last updated:2025-03-06 08:32:39
| Boiling point | 514.5±50.0 °C(Predicted) |
|---|---|
| Density | 1.103±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 11.85±0.46(Predicted) |
| InChI | InChI=1S/C20H25NO3/c1-20(2,3)24-19(23)21-18(14-22)13-15-9-11-17(12-10-15)16-7-5-4-6-8-16/h4-12,18,22H,13-14H2,1-3H3,(H,21,23)/t18-/m1/s1 |
| InChIKey | TYQICOFAZDVKMK-GOSISDBHSA-N |
| SMILES | C(OC(C)(C)C)(=O)N[C@@H](CO)CC1=CC=C(C2=CC=CC=C2)C=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
LCZ696 InteMediate price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B397950 | N-[(1R)-2-[1,1''-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]-carbamicAcid1,1-DimethylethylEster | 1426129-50-1 | 10g | $880 | 2021-12-16 | Buy |
| AK Scientific | X3805 | (R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate | 1426129-50-1 | 25g | $967 | 2021-12-16 | Buy |
| AK Scientific | J56908 | (R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate | 1426129-50-1 | 25g | $725 | 2021-12-16 | Buy |
| Ambeed | A120802 | (R)-tert-Butyl(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate 95% | 1426129-50-1 | 250mg | $5 | 2021-12-16 | Buy |
| Ambeed | A120802 | (R)-tert-Butyl(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate 95% | 1426129-50-1 | 1g | $7 | 2021-12-16 | Buy |
LCZ696 InteMediate Chemical Properties,Uses,Production
Description
LCZ696 InteMediate is chemically known as (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbaMate. It is a pharmaceutical intermediate compound and a by-product in the preparation of LCZ696 (Sacubitril/valsartan). LCZ696 InteMediate can also be used to synthesize (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid.
Uses
LCZ696 InteMediate is a useful intermediate for preparing Sacubitril (S080900)/Valsartan (V095750).
LCZ696 InteMediate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 308)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Yutian pharmaceutical Co.,Ltd. | +undefined-0518-86098006 +undefined19851887368 | lvan.hui@jsytsw.com | China | 80 | 58 |
| ChemExpress | +86-021-58950125 +86-021-58950125; | info@chemexpress.com | China | 782 | 58 |
| Zhejiang guotuohuanuo pharmatech Co.,Ltd, | +86-18600013947 +86-18600013947 | prp336019@vip.163.com | China | 32 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531157085 | abby@chuanghaibio.com | China | 8808 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12810 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 | info@dakenam.com | China | 19809 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 810 | 58 |
View Lastest Price from LCZ696 InteMediate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-23 | LCZ696 InteMediate
1426129-50-1
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-03-21 | LCZ696 InteMediate
1426129-50-1
|
US $0.00 / KG | 1KG | 99% | 20tons | Hebei Mujin Biotechnology Co.,Ltd | |
 |
2025-03-06 | LCZ696 InteMediate
1426129-50-1
|
US $0.00 / kg | 1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- LCZ696 InteMediate
1426129-50-1
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- LCZ696 InteMediate
1426129-50-1
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- LCZ696 InteMediate
1426129-50-1
- US $0.00 / kg
- 99%
- Shaanxi Dideu New Materials Co. Ltd
1426129-50-1(LCZ696 InteMediate)Related Search:
Sacubitril Impurity 10
LCZ696
LCZ Impurity
(S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one
Sacubitril Impurity 72
2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)-
(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid
(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoic acid
(S)-5-[(Biphenyl-4-yl)carbonyl]pyrrolidin-2-one
LCZ696 interMediate
Valsartan
(2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid
(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate
((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester
(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoate
1of4
tert-butyl (R)-(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
1)(R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamic acid 1,1-dimethylethyl ester
LCZ696 InteMediate
(R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbaMate
LCZ696 InteMediate USP/EP/BP
N-[(1R)-2-[1,1’-biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamic acid
(R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-y...
D-N-Boc-biphenyl propanol
(R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamateQ: What is
(R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate Q: What is the CAS Number of
(R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate Q: What is the storage condition of
(R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate Q: What are the applications of
(R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
(R)-tert-butyl (1-([1
1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
LCZ-696 Intermediate 39
EOS-61581
Carbamic acid, N-[(1R)-2-[1,1'-biphenyl]-4-yl-1-(hydroxymethyl)ethyl]-, 1,1-dimethylethyl ester
N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxyethyl)ethyl]carbamic acid 1,1-dimethylethyl ester
(2-Biphenyl-4-yl-1-hydroxymethyl-ethyl)-carbamic acid tert-butyl ester
LCZ696interN-3
(R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbaMate1426129-50-1
(1-([1,1'-biphenyL
)-3-hydroxypropan-2-yL
tert-butylN-[(2R)-1-hydroxy-3-(4-phenylphenyl)propan-2-yl]carbamate
LCZ696(valsartan + sacubitril) impurity 29
(R) -tert-butyl (1-([1,1'-biphenyl] -4-yl) -3-hydroxypropane-2-yl) carbamate
(R)-tert-butyl 1-(biphenyl-4-yl)-3-hydroxypropan-2-ylcarbamate
(R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxy
Benzenamine,2-bromo-10-methyl-
Methanol,3-chloro-,benzoate
1,4-Benzenedicarboxylicacid,bis(4-methylethyl)ester
low price LCZ696 Intermediate
1,1-Dimethylethyl N-[(1R)-2-[1,1'-biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamate
AMINO DIPHENYL METHANOL
Sacubitril Impurity 78
tert-Butyl N-(1R)-2-biphenyl-4-yl-1-(hydroxymethyl)ethylcarbamate
150kg
(R)-2-(Boc-amino)-3-(4-biphenylyl)-1-propanol
LCZ696 InteMediate I
Shakubiqu 50-1
LCZ696 Intermediate A-1
Calcium bis(4-{[(2S,4R)-1-(4-biphenylyl)-5-ethoxy-4-methyl-5-oxo-2-pentanyl]amino}-4-oxobutanoate)
(R)-tert-Butyl(-1-([1,1'-biphenyl]-3-yl)-3-hydroxypropan-2-yl)carbamate
1426129-50-1
LCZ696
LCZ 696
1426129-50-1