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LCZ696 InteMediate

LCZ696 InteMediate structure

CAS No.: 1426129-50-1

Chemical Name:: LCZ696 InteMediate

Synonyms: (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbaMate;tert-butyl (R)-(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate;(R)-tert-butyl 1-(biphenyl-4-yl)-3-hydroxypropan-2-ylcarbamate;N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamic acid 1,1-dimethylethyl ester;Carbamic acid, N-[(1R)-2-[1,1'-biphenyl]-4-yl-1-(hydroxymethyl)ethyl]-, 1,1-dimethylethyl ester;150kg;EOS-61581;LCZ696interN-3;Shakubiqu 50-1;Compound X3805

CBNumber:: CB82723677

Molecular Formula:: C20H25NO3

Molecular Weight:: 327.42

MDL Number:: MFCD28359221

MOL File:: 1426129-50-1.mol

MSDS File:: SDS

Last updated:2026-05-28 06:09:17

Product description	Number	Pack Size	Price
N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]-carbamic Acid1,1-Dimethylethyl Ester	BHC12950	5g	$900
N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]-carbamic Acid1,1-Dimethylethyl Ester	BHC12950	50g	$900
N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]-carbamic Acid1,1-Dimethylethyl Ester	BHC12950	2g	$900
N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]-carbamic Acid1,1-Dimethylethyl Ester	BHC12950	25g	$900
N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]-carbamic Acid1,1-Dimethylethyl Ester	BHC12950	10g	$900
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LCZ696 InteMediate Properties

Boiling point	514.5±50.0 °C(Predicted)
Density	1.103±0.06 g/cm3(Predicted)
storage temp.	2-8°C
pka	11.85±0.46(Predicted)
Appearance	Off-white to light yellow Solid
optical activity	26.1434°(C=0.1946g/100ml MEOH)
InChI	InChI=1S/C20H25NO3/c1-20(2,3)24-19(23)21-18(14-22)13-15-9-11-17(12-10-15)16-7-5-4-6-8-16/h4-12,18,22H,13-14H2,1-3H3,(H,21,23)/t18-/m1/s1
InChIKey	TYQICOFAZDVKMK-GOSISDBHSA-N
SMILES	C(OC(C)(C)C)(=O)N[C@@H](CO)CC1=CC=C(C2=CC=CC=C2)C=C1

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P280-P305+P351+P338

LCZ696 InteMediate price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	BHC12950	N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]-carbamic Acid1,1-Dimethylethyl Ester	1426129-50-1	5g	$900	2026-06-04	Buy
Biosynth	BHC12950	N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]-carbamic Acid1,1-Dimethylethyl Ester	1426129-50-1	50g	$900	2026-06-04	Buy
Biosynth	BHC12950	N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]-carbamic Acid1,1-Dimethylethyl Ester	1426129-50-1	2g	$900	2026-06-04	Buy
Biosynth	BHC12950	N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]-carbamic Acid1,1-Dimethylethyl Ester	1426129-50-1	25g	$900	2026-06-04	Buy
Biosynth	BHC12950	N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]-carbamic Acid1,1-Dimethylethyl Ester	1426129-50-1	10g	$900	2026-06-04	Buy

Product number	Packaging	Price	Buy
BHC12950	5g	$900	Buy
BHC12950	50g	$900	Buy
BHC12950	2g	$900	Buy
BHC12950	25g	$900	Buy
BHC12950	10g	$900	Buy

LCZ696 InteMediate Chemical Properties,Uses,Production

Description

LCZ696 InteMediate is chemically known as (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbaMate. It is a pharmaceutical intermediate compound and a by-product in the preparation of LCZ696 (Sacubitril/valsartan). LCZ696 InteMediate can also be used to synthesize (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid.

Uses

LCZ696 InteMediate is a useful intermediate for preparing Sacubitril (S080900)/Valsartan (V095750).

LCZ696 InteMediate synthesis

Synthesis of LCZ696 InteMediate from BOC-D-4,4'-BIPHENYLALANINE

LCZ696 InteMediate Preparation Products And Raw materials

Raw materials

METHYL-N-TERT-BUTYLOXYCARBONYL-AMINO-4,4'-BIPHENYL-R-ALANINE BOC-D-4,4'-BIPHENYLALANINE

Preparation Products

LCZ696 InteMediate Suppliers

Global( 330)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Jiangsu Yutian pharmaceutical Co.,Ltd.	+undefined-0518-86098006 +undefined19851887368	lvan.hui@jsytsw.com	China	80	58
Zhejiang guotuohuanuo pharmatech Co.,Ltd,	+86-18600013947	prp336019@vip.163.com	China	31	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971	deasea125996@gmail.com	China	2472	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	14026	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21585	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60

Supplier	Advantage
Jiangsu Yutian pharmaceutical Co.,Ltd.	58
Zhejiang guotuohuanuo pharmatech Co.,Ltd,	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Bao Enluo International TradeCo.，LTD	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Hi-Tech Chemistry Corp	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60

View Lastest Price from LCZ696 InteMediate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-06-30	LCZ696 InteMediate 1426129-50-1		1kg	99%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2026-03-20	LCZ696 InteMediate 1426129-50-1	$10.00	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2026-02-02	LCZ696 InteMediate 1426129-50-1	$1.00	1g	99%	50tons	Shaanxi Dideu Medichem Co. Ltd

LCZ696 InteMediate
1426129-50-1
$0.00
99%
Shaanxi Dideu New Materials Co. Ltd

LCZ696 InteMediate
1426129-50-1
$10.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

LCZ696 InteMediate
1426129-50-1
$1.00
99%
Shaanxi Dideu Medichem Co. Ltd

1426129-50-1(LCZ696 InteMediate)Related Search:

Sacubitril Impurity 10 LCZ696 LCZ Impurity (S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one Sacubitril Impurity 72

2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoic acid (S)-5-[(Biphenyl-4-yl)carbonyl]pyrrolidin-2-one LCZ696 interMediate

Valsartan (2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate ((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoate

AHU-377 (R,E)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate (2R,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid

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1)(R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate LCZ696 InteMediate LCZ696 InteMediate USP/EP/BP N-[(1R)-2-[1,1’-biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamic acid (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-y... D-N-Boc-biphenyl propanol (R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamateQ: What is (R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate Q: What is the CAS Number of (R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate Q: What is the storage condition of (R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate Q: What are the applications of (R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate (R)-tert-butyl (1-([1 1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate LCZ-696 Intermediate 39 EOS-61581 N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxyethyl)ethyl]carbamic acid 1,1-dimethylethyl ester (2-Biphenyl-4-yl-1-hydroxymethyl-ethyl)-carbamic acid tert-butyl ester LCZ696interN-3 (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbaMate1426129-50-1 (1-([1,1'-biphenyL )-3-hydroxypropan-2-yL tert-butylN-[(2R)-1-hydroxy-3-(4-phenylphenyl)propan-2-yl]carbamate LCZ696(valsartan + sacubitril) impurity 29 (R) -tert-butyl (1-([1,1'-biphenyl] -4-yl) -3-hydroxypropane-2-yl) carbamate (R)-tert-butyl 1-(biphenyl-4-yl)-3-hydroxypropan-2-ylcarbamate (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxy Benzenamine,2-bromo-10-methyl- Methanol,3-chloro-,benzoate 1,4-Benzenedicarboxylicacid,bis(4-methylethyl)ester low price LCZ696 Intermediate 1,1-Dimethylethyl N-[(1R)-2-[1,1'-biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamate AMINO DIPHENYL METHANOL Sacubitril Impurity 78 tert-Butyl N-(1R)-2-biphenyl-4-yl-1-(hydroxymethyl)ethylcarbamate 150kg (R)-2-(Boc-amino)-3-(4-biphenylyl)-1-propanol LCZ696 InteMediate I Shakubiqu 50-1 LCZ696 Intermediate A-1 Calcium bis(4-{[(2S,4R)-1-(4-biphenylyl)-5-ethoxy-4-methyl-5-oxo-2-pentanyl]amino}-4-oxobutanoate) (R)-tert-Butyl(-1-([1,1'-biphenyl]-3-yl)-3-hydroxypropan-2-yl)carbamate (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3- (R)-tert-butyl (1-([1, 1'-biphenyl]-4-base)-3-Hydroxypropane-2-base)Carbamate Compound X3805 (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbaMate Carbamic acid, N-[(1R)-2-[1,1'-biphenyl]-4-yl-1-(hydroxymethyl)ethyl]-, 1,1-dimethylethyl ester N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamic acid 1,1-dimethylethyl ester tert-butyl (R)-(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate 1426129-50-1 LCZ696 LCZ 696 1426129-50-1