Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>FMoc-α-Me-Lys(Boc)-OH

FMoc-α-Me-Lys(Boc)-OH

FMoc-α-Me-Lys(Boc)-OH Structure
FMoc-α-Me-Lys(Boc)-OH structure
CAS No.
1202003-49-3
Chemical Name:
FMoc-α-Me-Lys(Boc)-OH
Synonyms
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)-2-methylhexanoic acid;Fmoc-a-Me-Lys(Boc)-OH;Fmoc-α-Me-Lys(Boc)-OH;Fmoc-alpha-Me-Lys(Boc)-OH;Fmoc-α-methyl-L-Lysine(Boc);Fmoc-alpha-Me-L-Lys(Boc)-OH;FMoc-α-Me-Lys(Boc)-OH USP/EP/BP;N6-Boc-N2-Fmoc-alfa-Me--L-Lys-OH;N6-Boc-N2-Fmoc-2-methyl-L-Lysine;(S)-Na-Fmoc-NW-Boc-α-Methyllysine
CBNumber:
CB82729321
Molecular Formula:
C27H34N2O6
Molecular Weight:
482.57
MDL Number:
MFCD17019258
MOL File:
1202003-49-3.mol
Last updated:2023-04-27 16:27:43
Request For Quotation

FMoc-α-Me-Lys(Boc)-OH Properties

Boiling point 687.9±55.0 °C(Predicted)
Density 1.196±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 3.92±0.41(Predicted)
form powder
color white
InChIKey MYQXEVZHWDILHG-MHZLTWQESA-N
SMILES C(O)(=O)[C@](C)(CCCCNC(OC(C)(C)C)=O)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335-H336-H351-H373
Precautionary statements  P261-P281-P305+P351+P338
Hazard Codes  Xn
Risk Statements  36/37/38-40-67
Safety Statements  23-24/25-36/37
TSCA  No

FMoc-α-Me-Lys(Boc)-OH price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC F647540 (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)-2-methylhexanoicAcid 1202003-49-3 10mg $60 2021-12-16 Buy
AK Scientific 0415AP Fmoc-alpha-Me-Lys(Boc)-OH 1202003-49-3 25mg $95 2021-12-16 Buy
ChemSupplyAustralia 300598 (S)-Nα-Fmoc-Nω-Boc-α-Methyllysine, 98% 1202003-49-3 100mg $121 2021-12-16 Buy
Activate Scientific AS115441 (S)-Na-Fmoc-Nw-Boc-alpha-methyllysine 97+% ee 1202003-49-3 100mg $194 2021-12-16 Buy
AK Scientific 0415AP Fmoc-alpha-Me-Lys(Boc)-OH 1202003-49-3 100mg $217 2021-12-16 Buy
Product number Packaging Price Buy
F647540 10mg $60 Buy
0415AP 25mg $95 Buy
300598 100mg $121 Buy
AS115441 100mg $194 Buy
0415AP 100mg $217 Buy

FMoc-α-Me-Lys(Boc)-OH Chemical Properties,Uses,Production

Chemical Properties

White to off-white powder.

Uses

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)-2-methylhexanoic acid is a reagent in the preparation/biological evaluation of a vapreotide analogs containing (S)-α-methyl-lysine.

Uses

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)-2-methylhexanoic acid is a reagent in the preparation/biological evaluation of a vapreotide analogs containing (S)?-?α-?methyl-?lysine.

Synthesis

Benzyl (2R,3S)-(?)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate (4) was successively alkylated with methyl iodide and 1,4-diiodobutane using a base. In each alkylation step anti-alkylated product formed exclusively. The iodo group was displaced with azide, which served as a precursor for the side-chain amino function. Catalytic hydrogenation with concomitant cleavage of the chiral auxiliary afforded (L)-α-Me-Lys-OH (9) in a total of four steps in good yield. (L)-Fmoc-α-Me-Lys(Boc)-OH (16) was obtained from 9 via regioselective benzyloxycarbonylation. Alternately, (L)-Fmoc-α-Me-Lys(Boc)-OH (16) was obtained via Staudinger reduction of azide (8) in a total of six steps in good yield.

FMoc-α-Me-Lys(Boc)-OH synthesis

1202003-44-8
82911-69-1
1202003-49-3
Synthesis of FMoc-α-Me-Lys(Boc)-OH from H-α-Me-Lys(Boc)-OH and N-(9-Fluorenylmethoxycarbonyloxy)succinimide

FMoc-α-Me-Lys(Boc)-OH Preparation Products And Raw materials

Raw materials

L-Lysine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-2-methyl-, hydrochloride (1:1) Propanedioic acid, 2-[4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)butyl]-2-methyl-, 1,3-diethyl ester H-α-Me-Lys(Boc)-OH (2S)-6-amino-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylhexanoic acid Di-tert-butyl dicarbonate
N-(9-Fluorenylmethoxycarbonyloxy)succinimide

1of2

Preparation Products

FMoc-α-Me-Lys(Boc)-OH Suppliers

Global( 94)Suppliers
Supplier Tel Email Country ProdList Advantage
Apeloa Pharmaceutical Co., Ltd.
+86-0571-87635730 +8615858229168 chem1022@hengdian-group.com China 1469 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19915 58
Jiangxi Chiyan Biopharmaceutical Technology Co.,Ltd.
+86-18616643091 +86-18616643091 info@rochipharma.com China 246 58
Alpha Biopharmaceuticals Co., Ltd 		+86-411-39042497 +8613921981412 sales@alphabiopharm.com China 886 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Zhejiang ZETian Fine Chemicals Co. LTD 		18957127338 stella@zetchem.com China 2141 58
GL Biochem (Shanghai) Ltd. 		+86-021-61263370 +86-18901917034 CHINA 3904 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 29321 58
BOC Sciences 		+16314854226 inquiry@bocsci.com United States 19743 58
Hefei Hirisun Pharmatech Co., Ltd 		+8615056975894 shawn@hirisunpharm.com CHINA 9923 58
Supplier Advantage
Apeloa Pharmaceutical Co., Ltd.
58
Nextpeptide Inc
58
Jiangxi Chiyan Biopharmaceutical Technology Co.,Ltd.
58
Alpha Biopharmaceuticals Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Zhejiang ZETian Fine Chemicals Co. LTD 		58
GL Biochem (Shanghai) Ltd. 		58
Dideu Industries Group Limited 		58
BOC Sciences 		58
Hefei Hirisun Pharmatech Co., Ltd 		58

View Lastest Price from FMoc-α-Me-Lys(Boc)-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
FMoc-α-Me-Lys(Boc)-OH pictures 2022-10-09 FMoc-α-Me-Lys(Boc)-OH
1202003-49-3
 US $0.00-0.00 / KG 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.

1202003-49-3(FMoc-α-Me-Lys(Boc)-OH)Related Search:

Fmoc-α-Me-L-Dab(Boc)-OH Fmoc-α-Me-homoPhe-OH FMoc-α-Me-Trp(Boc)-OH (R)-N-FMoc-2-(6'-heptenyl)alanine (S)-N-FMoc-2-(2'--propynyl)alanine
(S)-N-Fmoc-2-(3'-butenyl)alanine FMoc-α-Me-D-Pro-OH FMoc-α-Me-Asp(OtBu)-OH (S)-N-FMoc-2-(5'-pentenyl)alanine (S)-N-FMoc-2-(6'-heptenyl)alanine
(S)-N-Fmoc-2-(2'-propylenyl)alanine FMoc-α-Me-D-Phe(2-F)-OH FMoc-α-Me-D-Orn(Boc)-OH Fmoc-α-methyl-L-Leucine FMOC-ALPHA-METHYL-L-PHE
FMoc-α-Me-D-Lys(Boc)-OH FMoc-α-Me-Orn(Boc)-OH Fmoc-alpha-methyl-D-leucine

1of4

N6-[(1,1-Dimethylethoxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-2-methyl-L-lysine (S)-N-ALPHA-FMOC-N-EPSILON-BOC-ALPHA-METHYLLYSINE (S)-NΑ-FMOC-NΩ-BOC-Α-METHYLLYSINE (S)-Na-Fmoc-NW-Boc-α-Methyllysine Fmoc-alpha-Me-L-Lys(Boc)-OH (2S)-6-{[(tert-butoxy)carbonyl]amino}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylhexanoic acid (9H-Fluoren-9-yl)MethOxy]Carbonyl Alpha-Methyl-Lys(Boc)-OH N6-Boc-N2-Fmoc-alfa-Me--L-Lys-OH (S)-N-ALPHA-FMOC-N-EPSILON-BOC-ALPHA-METHYLLYSINE, >97% Fmoc-a-Me-Lys(Boc)-OH Fmoc-α-methyl-L-Lysine(Boc) (S)-Na-Fmoc-Nw-Boc-A-Methyllysine Fmoc-alpha-Me-Lys(Boc)-OH L-Lysine, N6-[(1,1-dimethylethoxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-2-methyl- N6-Boc-N2-Fmoc-2-methyl-L-Lysine Fmoc-α-Me-Lys(Boc)-OH FMoc-α-Me-Lys(Boc)-OH USP/EP/BP N-α-(9-Fluorenylmethoxycarbonyl)-N-ε-(t-butoxycarbonyl)-α-methyl-L-lysine (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)-2-methylhexanoic acid (S)-Na-Fmoc-NW-Boc-α-Methyllysine 1202003-49-3 1202003-41-3 α-Methyl Amino Acids