ChemicalBook >> CAS DataBase List >>COENZYME Q1

COENZYME Q1

CAS No.
727-81-1
Chemical Name:
COENZYME Q1
Synonyms
Nsc 268269;COENZYME Q1;UBIQUINONE-5;Ubiquinone 1;Ubiquinone Q1;2-Isopentenyl-5,6-dimethoxy-3-methyl-p-benzoquinone;2,3-DIMETHOXY-5-METHYL-6-(3-METHYL-2-BUTENYL)-1,4-BENZOQUINONE;2,3-dimethoxy-5-methyl-6-(3-methylbut-2-enyl)cyclohexa-2,5-diene-1,4-dione;2,3-Dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-2,5-cyclohexadiene-1,4-dione;2,5-Cyclohexadiene-1,4-dione, 2,3-dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-
CBNumber:
CB8278506
Molecular Formula:
C14H18O4
Molecular Weight:
250.29
MDL Number:
MFCD00274412
MOL File:
727-81-1.mol
MSDS File:
SDS
Last updated:2023-06-08 09:02:31

COENZYME Q1 Properties

Boiling point 389.1±42.0 °C(Predicted)
Density 1.10±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMF: 10 mg/ml; Ethanol: 10 mg/ml
form Orange-red to red liquid.
FDA UNII JR17826E4G

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS02
Signal word  Danger
Safety Statements  23-24/25
WGK Germany  3
NFPA 704
3
0 0

COENZYME Q1 price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C7956 Coenzyme Q1 ≥95% 727-81-1 2mg $124 2024-03-01 Buy
Sigma-Aldrich C7956 Coenzyme Q1 ≥95% 727-81-1 10mg $373 2024-03-01 Buy
Cayman Chemical 18741 Coenzyme Q1 ≥98% 727-81-1 1mg $49 2024-03-01 Buy
Cayman Chemical 18741 Coenzyme Q1 ≥98% 727-81-1 5mg $190 2024-03-01 Buy
Sigma-Aldrich C7956 Coenzyme Q1 ≥95% 727-81-1 5x10mg $1500 2024-03-01 Buy
Product number Packaging Price Buy
C7956 2mg $124 Buy
C7956 10mg $373 Buy
18741 1mg $49 Buy
18741 5mg $190 Buy
C7956 5x10mg $1500 Buy

COENZYME Q1 Chemical Properties,Uses,Production

Description

Cooenzyme Q10 (CoQ10) is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. CoQ1 is an amphipathic CoQ10 homolog that has a tail consisting of five isoprene units. It has been used as an electron acceptor to study a range of oxidoreductases as isolated enzymes, in subcellular fractions, in intact cells in culture, and in perfused organs. Ubiquinone analogs, including CoQ1, impact mitochondrial permeability transition pore (PTP) formation, as well as PTP-dependent cell death, in an analog- and cell-specific manner.

Uses

Coenzyme Q1 is an electron acceptor and a component of the electron transport chain. It also play a role in the?mitochondrial permeability transition pore (PTP). Coenzyme Q1 is structurally similar to?coenzyme Q2 (C636450)?and?coenzyme Q10 (C636501).

Uses

Coenzyme Q1 has been used to measure the mitochondrial respiratory chain complex 1 activity.

Definition

ChEBI: Ubiquinones is any benzoquinone derived from 2,3-dimethoxy-5-methylbenzoquinone; one of a group of naturally occurring homologues. The redox-active quinoid moiety usually carries a polyprenoid side chain at position 6, the number of isoprenoid units in which is species-specific. Ubiquinones are involved in the control of mitochondrial electron transport, and are also potent anti-oxidants. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is a prenylquinone and a member of 1,4-benzoquinones. It is functionally related to a 2,3-dihydroxy-5-methyl-1,4-benzoquinone.

General Description

Coenzyme Q (CoQ) is localized to the hydrophobic domain of the phospholipid bilayer of mitochondria, plasma lipoproteins, and other biological membranes. It is a ubiquinone homolog with a short isoprenoid side chain.

Biochem/physiol Actions

Coenzyme Q1 (CoQ1) is a 1 isoprenyl group (not naturally occurring) member of a family of ubiquinones that share a quinine chemical group but differ in the number of isoprenyl chemical subunits in their tail. The CoQ compounds are lipid soluble components of cell membranes where they perform multiple functions such as electron and proton transport. The most well studied CoQ compound is CoQ10. CoQ1 is frequently used in comparison studies on the effect of isoprenyl chain length on CoQ functions or distribution and to identify quinone reductases.

COENZYME Q1 Preparation Products And Raw materials

Raw materials

Preparation Products

COENZYME Q1 Suppliers

Global( 40)Suppliers
Supplier Tel Email Country ProdList Advantage
Creative Enzymes
1-516-855-7709 info@creative-enzymes.com United States 8748 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Rhawn Reagent 400-400-1332688 18019345275 amy@rhawn.cn China 15503 58
Beijing OKA biological technology co., LTD 010-62971590 18548936886 3462612863@qq.com China 6912 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223 psaitong@jm-bio.com China 29834 58
2,3-DIMETHOXY-5-METHYL-6-(3-METHYL-2-BUTENYL)-1,4-BENZOQUINONE COENZYME Q1 UBIQUINONE-5 2,3-dimethoxy-5-methyl-6-(3-methylbut-2-enyl)cyclohexa-2,5-diene-1,4-dione Ubiquinone Q1 2,3-Dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-1,4-benzoquinone, Ubiquinone-1, Ubiquinone-5 2,3-Dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-2,5-cyclohexadiene-1,4-dione 2-Isopentenyl-5,6-dimethoxy-3-methyl-p-benzoquinone Ubiquinone 1 2,5-Cyclohexadiene-1,4-dione, 2,3-dimethoxy-5-methyl-6-(3-methyl-2-butenyl)- Nsc 268269 2,5-Cyclohexadiene-1,4-dione, 2,3-dimethoxy-5-methyl-6-(3-methyl-2-buten-1-yl)- 727-81-1 Electron Transport and Cellular Respiration Cofactors and Substrates Metabolomics Metabolic Pathways BioChemical