D-Luciferin | 2591-17-5

D-Luciferin Properties

Melting point	200-204 °C
alpha	D22 -36° (c = 1.2 in DMF)
Boiling point	587.6±60.0 °C(Predicted)
Density	1.4916 (rough estimate)
refractive index	1.5650 (estimate)
storage temp.	-20°C
solubility	DMF:30.0(Max Conc. mg/mL);107.02(Max Conc. mM) DMSO:35.33(Max Conc. mg/mL);126.05(Max Conc. mM)
pka	8.31±0.40(Predicted)
form	Powder
color	Off-white to light yellow
λmax	360nm(H2O)(lit.)
Merck	14,4086
BRN	30484
InChI	InChI=1S/C11H8N2O3S2/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16/h1-3,7,14H,4H2,(H,15,16)/t7-/m1/s1
InChIKey	BJGNCJDXODQBOB-SSDOTTSWSA-N
SMILES	S1C[C@H](C(O)=O)N=C1C1=NC2=CC=C(O)C=C2S1
FDA UNII	5TBB02N29K

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P271-P280
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36/37/39-24/25
WGK Germany	3
F	8-10
HS Code	29342000

D-Luciferin price More Price(38)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	L6152	D-Luciferin synthetic, BioXtra, ≥99% (HPLC)	2591-17-5	1mg	$279	2024-03-01	Buy
Sigma-Aldrich	L6152	D-Luciferin synthetic, BioXtra, ≥99% (HPLC)	2591-17-5	10mg	$1380	2024-03-01	Buy
TCI Chemical	A5030	D-(-)-Luciferin [Chemiluminescence Reagent] >98.0%(HPLC)	2591-17-5	10mg	$204	2024-03-01	Buy
TCI Chemical	A5030	D-(-)-Luciferin [Chemiluminescence Reagent] >98.0%(HPLC)	2591-17-5	50mg	$622	2024-03-01	Buy
Cayman Chemical	25836	D-Luciferin ≥98%	2591-17-5	10mg	$37	2024-03-01	Buy

Product number	Packaging	Price	Buy
L6152	1mg	$279	Buy
L6152	10mg	$1380	Buy
A5030	10mg	$204	Buy
A5030	50mg	$622	Buy
25836	10mg	$37	Buy

D-Luciferin Chemical Properties,Uses,Production

Description

D-Luciferin is a popular bioluminescent substrate of luciferase in the presence of ATP, used in luciferase-based bioluminescence imaging and cell-based high-throughput screening applications. In an immunocompetent mouse model of ovarian cancer, the use of D-luciferin substrate and firefly luciferase preserves tumour-host immune interactions since bioluminescent imaging is a more sensitive indication of tumour growth than weight gain.

Chemical Properties

off-white to light yellow powder

Uses

D-Luciferin has been used in the preparation of the reaction mixture for nitric oxide determination by minescence measurement. It has also been used in the preparation of D-luciferin stock solution for luciferin assays.

Uses

In the assay of ATP.

Uses

D-Luciferin has been used in determining luciferase activity by luciferase assay in mice and Arabidopsis thaliana seeds. It has also been used in measuring bioluminescence in neonatal rat ventricular cardiomyocytes.

Definition

ChEBI: A 1,3-thiazolemonocarboxylic acid consisting of 3,5-dihydrothiophene-4-carboxylic acid having a 6-hydroxybenzothiazol-2-yl group at the 2-position.

General Description

D-Luciferin is a small molecule present abundantly in bioluminescent organisms. This molecule is sensitive to oxygen and light.

Biochem/physiol Actions

D-Luciferin uptake within the cells is regulated by the adenosine triphosphate (ATP)-binding cassette (ABC) transporter inhibitors like ATP-binding cassette transporter G2 (ABCG2)/ breast cancer resistance protein (BCRP) inhibitor fumitremorgin C. This substrate is oxidized by firefly luciferase that results in emitting a photon, which has the capability of passing through living tissues.

Purification Methods

D-Luciferin crystallises as pale yellow needles from H2O, or MeOH (83mg/7mL). It has UV max at 263 and 327nm (log 3.88 and 4.27) in 95% EtOH. The Na salt has a solubility of 4mg in 1 mL of 0.05M glycine. [White et al. J Am Chem Soc 83 2402 1961, 85 337 1963, UV and IR: Bitler & McElroy Arch Biochem 72 358 1957, Review: Cormier et al. Fortschr Chem Org Naturst 30 1 1973, Beilstein 27 III/IV 8934.]

D-Luciferin Preparation Products And Raw materials

Raw materials

Preparation Products

D-Luciferin Suppliers

Global( 323)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Wuhan Mayue Longteng Technology Development Co., Ltd.	+undefined15171477138	helen.yan@lantu-tech.com	China	287	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	967	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5738	58
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd	+86-86-22-87899925 +86-8618522618860	18522618860@163.com	China	694	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58

Supplier	Advantage
Wuhan Mayue Longteng Technology Development Co., Ltd.	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Biochempartner	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from D-Luciferin manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-02-16	D-luciferin 2591-17-5	US $0.00 / G	10G	98%min	30kg/month	WUHAN FORTUNA CHEMICAL CO., LTD
2022-09-08	D-Luciferin 2591-17-5	US $0.00-0.00 / KG	1KG	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2019-07-06	D-LUCIFERIN 2591-17-5	US $1.00 / kg	1kg	98%	100KG	Career Henan Chemical Co

D-luciferin
2591-17-5
US $0.00 / G
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

D-Luciferin
2591-17-5
US $0.00-0.00 / KG
98%
Henan Aochuang Chemical Co.,Ltd.

D-LUCIFERIN
2591-17-5
US $1.00 / kg
98%
Career Henan Chemical Co

D-Luciferin Spectrum

D-LUCIFERIN(2591-17-5)¹HNMR

2591-17-5(D-Luciferin)Related Search:

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D-Luciferin sodium salt L-LUCIFERIN,L-Luciferin free acid, 99%,L-Luciferin free acid, 99%,L-LUCIFERIN LUCIFERASE 6-Benzothiazolol(7CI,8CI,9CI) D-luciferin 6-O-phosphate sodium,D-LUCIFERIN 6'-O-PHOSPHATE TRISODIUM &,D-LUCIFERIN 6'-O-PHOSPHATE TRISODIUM &,D-luciferin 6-O-phosphate sodium

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4,5-DIHYDRO-2-(6-HYDROXY-2-BENZOTHIAZOLYL)-4-THIAZOLECARBOXY 4,5-DIHYDRO-2-[6-HYDROXY-2-BENZOTHIAZOLYL]-4-THIAZOLE-CARBOXYLIC ACID 4,5-DIHYDRO-(6-HYDROXY-2-BENZOTHIAZOYL)-4-THIAZOLE CARBOXYLIC ACID LUCIFERIN, D- LUCIFERIN D(-)-2-(6'-HYDROXY-BENZOTHIAZOLYL)-DELTA2-THIAZOLINE-4-CARBOXYLIC ACID D(-)-LUCIFERIN D-LUCIFERIN D-LUCIFERIN FIREFLY D-Luciferin≥ 99% (HPLC) Photinus luciferin (S)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4 thiazolecarboxylic acid (4S)-2-(6-Hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid FIREFLY LUCIFERIN BEETLE LUCIFERIN AURORA KA-6717 (S)-2-[6-HYDROXY-2-BENZOTHIAZOLYL]-2-THIAZOLENE-4 (S)-2-(6-HYDROXY-2-BENZOTHIAZOLYL)-2-THIAZOLINE-4-CARBOXYLIC ACID (S)-4,5-dihydro-2-(6-hydroxybenzothiazol-2-yl)thiazole-4-carboxylic acid D-Luciferin free acid, 99% D-LUCIFERIN SYNTHETIC D-LUCIFERIN SIGMAULTRA D -LUCIFERIN SYNTHETIC CRYSTALLINE Beetle luciferin Firefly luciferin D-LUCIFERIN,FREEACID,ULTRAPURE D-Leciferin (4S)-2-(6-hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid D-(-)-Luciferin (D)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid, Firefly (synthetic), 99% D-LUCIFERINFREEACID,99% D-Luciferin, Free acid >99.5% 2-(6-Hydroxy-benzothiazol-2-yl)-thiazole-4-carboxylic acid D-Luciferin Firefly Luciferin, (S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic acid, 4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid (4S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4β-carboxylic acid (4S)-2-(6-Hydroxybenzothiazole-2-yl)-2-thiazoline-4-carboxylic acid D-(-)-Luciferin [Chemiluminescence Reagent] (4S)-4,5-Dihydro-(6-hydroxy-2-benzothiazoyl)-4-thiazolecarboxylic acid (S)-2-(6-hydroxybenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid D-Luciferin, free acid *CAS#: 2591-17-5* Luciferin, D- - Firefly Luciferin 2-(6-oxo-1,3-benzothiazol-2-ylidene)-4-thiazolidinecarboxylic acid D-(-)-Luciferin [Chemiluminescence Reagent]> uciferin 4-Thiazolecarboxylic acid, 4,5-dihydro-2-(6-hydroxy-2-benzothiazolyl)-, (4S)- D-luciferin (Firefly luciferin) D-Luciferin ex. Firefly, 99% 7-Dihydroxyflavone D-Luciferin Firefly, Free Acid 2591-17-5 2951-17-5 C11H7FN2O3S2 Biochemicals and Reagents Analytical Enzymes BioChemical Enzymes, Inhibitors, and Substrates Detection Fluorescent Probes, Labels, Particles and Stains Luciferase