Bopindolol
- CAS No.
- 62658-63-3
- Chemical Name:
- Bopindolol
- Synonyms
- Bopindolol;rac Bopindolol;Bopindolol USP/EP/BP;1-(tert-ButylaMino)-3-((2-Methyl-1H-indol-4-yl)oxy)propan-2-yl benzoate;2-[(1,1-Dimethylethyl)amino]-1-{[(2-methyl-1H-indol-4-yl)oxy]methyl}ethyl benzoate;1-[(1,1-DiMethylethyl)aMino]-3-[(2-Methyl-1H-indol-4-yl)oxy]-2-propanol 2-Benzoate;2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[(2-methyl-1H-indol-4-yl)oxy]-, 2-benzoate;2-PROPANOL, 1-[(1,1-DIMETHYLETHYL)AMINO]-3-[(2-METHYL-1H-INDOL-4-YL)OXY]-, BENZOATE (ESTER);(±)-1-[(1,1-DiMethylethyl)aMino]-3-[(2-Methyl-1H-indol-4-yl)oxy]-2-propanol Benzoate (Ester)
- CBNumber:
- CB8294403
- Molecular Formula:
- C23H28N2O3
- Molecular Weight:
- 380.48
- MDL Number:
- MFCD00864589
- MOL File:
- 62658-63-3.mol
- MSDS File:
- SDS
| Melting point | 117-120°C |
|---|---|
| Boiling point | 557.0±50.0 °C(Predicted) |
| Density | 1.143±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated) |
| pka | 17.59±0.30(Predicted) |
| form | Solid |
| color | White to Pale Beige |
| FDA UNII | KT304VZO57 |
| ATC code | C07AA17 |
Bopindolol price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B675400 | racBopindolol | 62658-63-3 | 5mg | $185 | 2021-12-16 | Buy |
| AK Scientific | C962 | Bopindolol | 62658-63-3 | 1mg | $191 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB37307 | Bopindolol | 62658-63-3 | 5mg | $300 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB37307 | Bopindolol | 62658-63-3 | 10mg | $520 | 2021-12-16 | Buy |
| AK Scientific | C962 | Bopindolol | 62658-63-3 | 10mg | $752 | 2021-12-16 | Buy |
Bopindolol Chemical Properties,Uses,Production
Description
Bopindolol is a potent, long-acting, non-selective β-adrenergic blocker related to pindolol and useful in the treatment of hypertension. Unlike many other agents of this type, it appears to have negligible effects on serum lipoproteins.
Chemical Properties
Off-White to pale Yellow Solid
Originator
sandoz (Switzerland)
Uses
Bopindolol is an ester prodrug of Pindolol (P468000). Bopindolol is a long acting β-adrenoceptor blocking agent. Bopindolol displays antispasmogenic activity mediated by α1-adrenoceptors and 5-HT2 receptors.
Definition
ChEBI: 1-(tert-butylamino)-3-[(2-methyl-1H-indol-4-yl)oxy]propan-2-yl benzoate is a methylindole that is 2-methyl-1H-indol-4-ol in which the hydrogen of the hydroxy group is replaced by a 2-(benzoyloxy)-3-(tert-butylamino)propyl group. It is a methylindole, a secondary amino compound, an aromatic ether and a benzoate ester.
Manufacturing Process
4-(2-Benzoyloxy-3-t-butylaminopropoxy)-2-methyl-indole:
26 g of benzoic acid are dissolved, while heating, in 50 ml of
hexamethylphosphoric acid triamide and 3.5 g of 1-t-butylamino-3-(2-methylindole-
4-yloxy)-2-propanol are added. After cooling, 3.0 g of benzoic acid
anhydride are added and stirred for 20 hours at room temperature. The
resulting clear, yellow solution is poured onto ice 0.5 liters of ether are added
and stirred for 2 hours. After making the liquid alkaline with concentrated
ammonia, the ether phase is separated, shaken out with tartaric acid, made
alkaline with caustic soda solution while cooling with ice and extracted with
methylene chloride. After evaporating the solvent, the residue is crystallized
with 1 mol of fumaric acid from methanol and acetone.
brand name
SANDONORM
Therapeutic Function
Beta-adrenergic blocker
Bopindolol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 | 1057@dideu.com | China | 3586 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29271 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Angel Pharmatech, Ltd. | 17317130613 | 3358272972@qq.com | China | 3237 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 021-61109150 | sales@tcisct.com | China | 31183 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
View Lastest Price from Bopindolol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-13 | Bopindolol USP/EP/BP
62658-63-3
|
US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-05-12 | rac Bopindolol
62658-63-3
|
US $1.00 / KG | 1KG | 99% | 20T | Shaanxi Dideu Medichem Co. Ltd |
-
- Bopindolol USP/EP/BP
62658-63-3
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- rac Bopindolol
62658-63-3
- US $1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd