Mirin
- CAS No.
- 1198097-97-0
- Chemical Name:
- Mirin
- Synonyms
- CS-2593;(Z)-Mirin;(Z)-Mirin,Inhibitor,(Z)Mirin,(Z) Mirin,inhibit;(Z)-2-Amino-5-(4-hydroxybenzylidene)thiazol-4(5H)-one;(5Z)-2-Amino-5-[(4-hydroxyphenyl)methylene]-4(5H)-thiazolone;4(5H)-Thiazolone, 2-amino-5-[(4-hydroxyphenyl)methylene]-, (5Z)-;(5Z) -2-amino-5- [(4-hydroxyphenyl) methylene] -4 (5H) - thiazolidone
- CBNumber:
- CB83037397
- Molecular Formula:
- C10H8N2O2S
- Molecular Weight:
- 220.25
- MDL Number:
- MFCD05885480
- MOL File:
- 1198097-97-0.mol
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H319-H315 |
Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
Mirin price More Price(17)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | M364938 | Mirin | 1198097-97-0 | 50mg | $225 | 2021-12-16 | Buy |
ApexBio Technology | B5389 | Mirin | 1198097-97-0 | 50mg | $228 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0004757 | 2-AMINO-5-[(4-HYDROXYPHENYL)METHYLENE]-, (5Z)-4(5H)-THIAZOLONE 95.00% | 1198097-97-0 | 5MG | $502.78 | 2021-12-16 | Buy |
ApexBio Technology | B5389 | Mirin | 1198097-97-0 | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
ApexBio Technology | B5389 | Mirin | 1198097-97-0 | 10mg | $83 | 2021-12-16 | Buy |
Mirin Chemical Properties,Uses,Production
Uses
Mirin is an MRN-ATM pathway inhibitor blocking 3’ and 5’ exonuclease activity associated with Mre11, inducing G2 cell cycle arrest.
Biological Activity
mirin is a potent mrn complex inhibitor. mirin inhibits mre11-associated exonuclease activity, rather than alters dna-binding or mrn complex formation. moreover, mirin prevents mrn-dependent activation of atm in response to dna double-strand breaks, with an ic50 value of 12 μm. the mrn complex acts as a dna damage sensor, responsible for maintaining genome stability during dna replication, promoting homology-dependent dna repair and activating atm. the mrn-atm pathway plays an essential role in sensing and signaling from dna double-strand breaks.1. dupré a, boyer-chatenet l, sattler rm, et al. a forward chemical genetic screen reveals an inhibitor of the mre11-rad50-nbs1 complex. nature chemical biology, 2008, 4(2): 119-125.
storage
Store at +4°C
Mirin Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 1000 | 58 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +8618829768577 | gao490372054@gamil.com | China | 1250 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
View Lastest Price from Mirin manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-04-12 | Mirin
1198097-97-0
|
US $0.00 / kg | 1kg | 99% | 2000ton | Shaanxi Haibo Biotechnology Co., Ltd | ||
2019-09-06 | (5Z)-2-Amino-5-[(4-hydroxyphenyl)methylene]-4(5H)-thiazolone
1198097-97-0
|
US $1.00 / ASSAYS | 1ASSAYS | 95%~99% | per week:100kg | Career Henan Chemical Co |
- Mirin
1198097-97-0
- US $0.00 / kg
- 99%
- Shaanxi Haibo Biotechnology Co., Ltd
- (5Z)-2-Amino-5-[(4-hydroxyphenyl)methylene]-4(5H)-thiazolone
1198097-97-0
- US $1.00 / ASSAYS
- 95%~99%
- Career Henan Chemical Co