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ChemicalBook >> CAS DataBase List >>(S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide

(S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide

(S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide Structure
(S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide structure
CAS No.
1448440-52-5
Chemical Name:
(S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide
Synonyms
CS-2845;SP-13786;UAMC-1110;UAMC-01110;SP 13786,SP13786;Fmoc-FAPI-4/ SCHEMBL21257089;SP-13786 (UAMC1110, FAP-IN-1);(S)-N-[2-(2-Cyano-4,4-difluoro-1-pyrrolidinyl)-2-oxoethyl]quinoline-4-carboxamide;(S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide;4-Quinolinecarboxamide, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-
CBNumber:
CB83052176
Molecular Formula:
C17H14F2N4O2
Molecular Weight:
344.32
MDL Number:
MFCD29477499
MOL File:
1448440-52-5.mol
Last updated:2023-05-18 11:31:00
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(S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide Properties

Melting point >70°C (Decomposed)
Boiling point 676.4±55.0 °C(Predicted)
Density 1.42±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Sparingly), Methanol (Slightly)
pka 12.43±0.46(Predicted)
form Solid
color Off-White to Pale Yellow
Stability Hygroscopic

(S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 153693 (S)-N-(2-(2-Cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide 95% 1448440-52-5 100mg $2960 2021-12-16 Buy
Matrix Scientific 153693 (S)-N-(2-(2-Cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide 95% 1448440-52-5 250mg $5514 2021-12-16 Buy
Chemenu CM328725 N-[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide 95%+ 1448440-52-5 10g $7728 2021-12-16 Buy
Crysdot CD11254374 SP-13786 97% 1448440-52-5 5mg $125 2021-12-16 Buy
Crysdot CD11254374 SP-13786 97% 1448440-52-5 10mg $194 2021-12-16 Buy
Product number Packaging Price Buy
153693 100mg $2960 Buy
153693 250mg $5514 Buy
CM328725 10g $7728 Buy
CD11254374 5mg $125 Buy
CD11254374 10mg $194 Buy

(S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide Chemical Properties,Uses,Production

Uses

UAMC1110 is a useful research chemical and a fibroblast activation protein inhibitor displaying low nanomolar inhibitory potency and high selectivity against related dipeptidyl peptidases.

(S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide synthesis

1448440-40-1
486-74-8
1448440-52-5
Synthesis of (S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide from (S)-1-(2-aminoacetyl)-4,4-difluoropyrrolidine-2-carbonitrile 2,2,2-trifluoroacetate and QUINOLINE-4-CARBOXYLIC ACID

(S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide Preparation Products And Raw materials

Raw materials

(S)-4,4-difluoropyrrolidine-2-carboxamide 2,2,2-trifluoroacetate N-Boc-4-oxo-L-Proline methyl ester N-Boc-trans-4-Hydroxy-L-proline methyl ester (S)-1-(2-aminoacetyl)-4,4-difluoropyrrolidine-2-carbonitrile 2,2,2-trifluoroacetate (S)-1-(2-aminoacetyl)-4,4-difluoropyrrolidine-2-carbonitrile 4-methylbenzenesulfonate
(S)-tert-butyl (2-(2-carbamoyl-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate (S)-tert-butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate BOC-4,4-DIFLUORO-L-PROLINE METHYL ESTER BOC-4,4-DIFLUORO-L-PROLINAMIDE N-BOC-4,4-difluoro-L-proline
QUINOLINE-4-CARBOXYLIC ACID

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Preparation Products

(S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide Suppliers

Global( 62)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
LEAP CHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 24738 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		+86-18341751992 +86-15382112998 757984502@qq.com China 892 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+undefined18621343501 product@acmec-e.com China 33349 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4121 55
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
InvivoChem 		58
LEAP CHEM CO., LTD. 		58
TargetMol Chemicals Inc. 		58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		58
Shanghai Acmec Biochemical Technology Co., Ltd. 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
Shanghai Lollane Biological Technology Co.,Ltd. 55

1448440-52-5((S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide)Related Search:

5-DIMETHYLAMINO-1-NAPHTHALENESULFONIC ACID HYDRATE Sulfanilamide
(S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide SP-13786 (S)-N-[2-(2-Cyano-4,4-difluoro-1-pyrrolidinyl)-2-oxoethyl]quinoline-4-carboxamide CS-2845 (S)-N-(2-(2-Cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide (UAMC1110) UAMC-1110 4-Quinolinecarboxamide, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]- SP-13786 (UAMC1110, FAP-IN-1) UAMC-01110 Fmoc-FAPI-4/ SCHEMBL21257089 SP 13786,SP13786 UAMC1110, (S)-N-(2-(2-cyano-4,4-difluoropyrrolidin- 1-yl)- 2-oxoethyl)quinoline-4-carboxamide 1448440-52-5