ChemicalBook >> CAS DataBase List >>H-VAL-NH2 HCL

H-VAL-NH2 HCL

H-VAL-NH2 HCL structure

CAS No.: 3014-80-0

Chemical Name:: H-VAL-NH2 HCL

Synonyms: L-Val-NH2;Val-Nh2.Hcl;H-Val-NH HCl;L-Val-NH2·HCl;VALINE-NH2 HC;H-VAL-NH2 HCL;VALINE-NH2 HCL;H-L-VAL-NH2 HCL;L-Valinamide HCl;L-VALINE AMIDE HCL

CBNumber:: CB8306409

Molecular Formula:: C5H12N2O.ClH

Molecular Weight:: 152.62

MDL Number:: MFCD00039085

MOL File:: 3014-80-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:13

Product description	Number	Pack Size	Price
L-Valinamide hydrochloride 97%	459232	5g	$63.1
L-Valinamide Hydrochloride >98.0%(N)(T)	V0102	5g	$31
L-Valinamide Hydrochloride >98.0%(N)(T)	V0102	25g	$89
L-ValineAmide	V094210	10g	$120
L-Valineamidehydrochloride,99%(HPLC) 99%(HPLC)	03166	250G	$571.2
More product size

Request For Quotation

H-VAL-NH2 HCL Properties

Melting point	266-270 °C(lit.)
refractive index	27 ° (C=1, H2O)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Soluble in methanol (50 mg/ ml-clear, colorless solution).
form	Solid
color	White to Almost white
optical activity	[α]25/D +25.8°, c = 1 in H2O
Major Application	peptide synthesis
InChI	InChI=1/C5H12N2O.ClH/c1-3(2)4(6)5(7)8;/h3-4H,6H2,1-2H3,(H2,7,8);1H/t4-;/s3
InChIKey	XFCNYSGKNAWXFL-NDILARRWNA-N
SMILES	[C@@H](N)(C(=O)N)C(C)C.Cl \|&1:0,r\|
UNSPSC Code	12352209
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P305+P351+P338

Safety Statements

24/25

WGK Germany

HS Code

29241990

Storage Class

11 - Combustible Solids

NFPA 704

	1
0		0

H-VAL-NH2 HCL price More Price(24)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	459232	L-Valinamide hydrochloride 97%	3014-80-0	5g	$63.1	2026-04-30	Buy
TCI Chemical	V0102	L-Valinamide Hydrochloride >98.0%(N)(T)	3014-80-0	5g	$31	2026-04-30	Buy
TCI Chemical	V0102	L-Valinamide Hydrochloride >98.0%(N)(T)	3014-80-0	25g	$89	2026-04-30	Buy
TRC	V094210	L-ValineAmide	3014-80-0	10g	$120	2021-12-16	Buy
Chem-Impex	03166	L-Valineamidehydrochloride,99%(HPLC) 99%(HPLC)	3014-80-0	250G	$571.2	2021-12-16	Buy

Product number	Packaging	Price	Buy
459232	5g	$63.1	Buy
V0102	5g	$31	Buy
V0102	25g	$89	Buy
V094210	10g	$120	Buy
03166	250G	$571.2	Buy

H-VAL-NH2 HCL Chemical Properties,Uses,Production

Chemical Properties

Crystalline

Uses

L-Valine Amide is a reagent used in the synthesis of alkylpyrazines. Also used in the synthesis of elastase inhibitory activity.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

72-18-4

7732-18-5

75-24-1

3014-80-0

Preparation of Example 9 (S)-2-Amino-3-methylbutyramide hydrochloride: anhydrous ammonia was passed into 150 mL of cooled dichloromethane (ice bath) at 0°C until the solution was saturated. The mixture was cooled to 5°C and trimethylaluminum (136.2 mL of a 2M hexane solution, 272.4 mmol) was added slowly and dropwise under nitrogen protection. The resulting turbid solution was warmed to room temperature and stirred for 22 hours. L-valine (10.6 g, 90.79 mmol) was added in batches and stirring was continued at room temperature for 18 hours. The reaction mixture was cooled to 0 °C (ice-water bath) and 190 mL of 6N hydrochloric acid was added slowly and dropwise until the pH reached 2. The mixture was warmed to room temperature and stirred for 2 h. Subsequently, the pH was adjusted to 11-12 with 10% aqueous sodium hydroxide. 100 mL of dichloromethane and 100 mL of water were added to the alkaline solution, the organic layer was separated, dried over magnesium sulfate and concentrated to dryness under reduced pressure. The residue was dissolved in 100 mL of dichloromethane and acidified by passing hydrogen chloride gas. The solid formed was collected by filtration and dried under reduced pressure to give 6.8 g (49% yield) of L-valine amide hydrochloride with melting point 258°-260°C. IR (Nujol, cm-1 ) showed C=O (1686) and N-H (3387,3241) absorption peaks.1H NMR and 13C NMR (CDCl3 ) data were consistent with the target product. Elemental analysis (C5H13ClN2O) Calculated values: C, 39.35; H, 8.59; N, 18.35; Cl, 23.23; Measured values: C, 39.82; H, 8.52; N, 18.40; Cl, 23.13. Mass spectra (MS): m/e 117 (M+-Cl).

References

[1] Patent: US5643855, 1997, A

H-VAL-NH2 HCL Preparation Products And Raw materials

Raw materials

L-Valine Water Trimethylaluminium Dichloromethane Hexane

Sodium hydroxide Hydrochloric acid Ammonia

1of2

Preparation Products

H-VAL-NH2 HCL Suppliers

Global( 324)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Taizhou Tianhong Biochemistry Technology Co., Ltd.	0523-86132544	sales@thbiochem.com	CHINA	305	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21590	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
AB PharmaTech,LLC	323-480-4688	sales@acrospharmatech.com	United States	989	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6369	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Taizhou Tianhong Biochemistry Technology Co., Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
AB PharmaTech,LLC	55
career henan chemical co	58
Accela ChemBio Inc.	58
Xiamen AmoyChem Co., Ltd	58
BOC Sciences	58

View Lastest Price from H-VAL-NH2 HCL manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-03-20	H-VAL-NH2 HCL 3014-80-0	US $25.00 / kg	100kg	99.5%	100 mt	Hebei Chuanghai Biotechnology Co., Ltd
2024-04-24	H-VAL-NH2 HCL 3014-80-0	US $10.00 / kg	1kg	99.8%	10000ton	Ouhuang Engineering Materials (Hubei) Co., Ltd
2019-07-06	H-VAL-NH2 HCL 3014-80-0	US $100.00 / KG	1KG	99%	Customized	Career Henan Chemical Co

H-VAL-NH2 HCL
3014-80-0
US $25.00 / kg
99.5%
Hebei Chuanghai Biotechnology Co., Ltd

H-VAL-NH2 HCL
3014-80-0
US $10.00 / kg
99.8%
Ouhuang Engineering Materials (Hubei) Co., Ltd

H-VAL-NH2 HCL
3014-80-0
US $100.00 / KG
99%
Career Henan Chemical Co

H-VAL-NH2 HCL Spectrum

H-VAL-NH2 HCL(3014-80-0)¹HNMR H-VAL-NH2 HCL(3014-80-0)IR

3014-80-0(H-VAL-NH2 HCL)Related Search:

H-VAL-PNA HCL H-NVA-NH2 HCL 1-Pyrrolidineaceticacid,alpha-ethylidene-2-oxo-,(alphaZ)-(9CI) 2-aminobutanenitrile 4-Chlorobutyryl chloride

4-CHLORO-BUTYRALDEHYDE L-Alaninamide hydrochloride Valeryl chloride ALPHA-METHYL-L-TRYPTOPHAN L-Valine benzyl ester hydrochloride

H-VAL-ILE-OH H-VAL-ALA-OH ALPHA-METHYL-L-VALINE HYDROCHLORIDE H-VAL-VAL-OH A-METHYL-L-TRYPTOPHAN

L-VALINE TERT-BUTYL ESTER HYDROCHLORIDE L-Valine methyl ester hydrochloride L-Valine benzyl ester 4-toluenesulfonate

1of4

(2S)-2-aMino-3-MethylbutyraMide hydrochloride VALINE-NH2 HC (S)-2-aMino-3-MethylbutanaMide hydrochloride L-Valinamide hydrochloride 97% H-Val-NH HCl L-Valinemide Hydrochloride L-Val-NH2 L-Val-NH2·HCl L-Valine amide hydrochloride≥ 99% (HPLC) H-Val-NH₂·HCl VALINE-NH2 HCL L-VALINAMIDE HYDROCHLORIDE L-VALINE AMIDE HCL L-VALINE AMIDE HYDROCHLORIDE H-VAL-NH2 HCL H-L-VAL-NH2 HCL L-VALINE AMIDE HCL 98+% Val-Nh2.Hcl L-Valinamide HCl H-Val-NH2·HCl (HPLC) L-Valine amide·hydrochloride salt Butanamide, 2-amino-3-methyl-, monohydrochloride, (2S)- Levetiracetam Impurity 39 L-VALINAMIDE HYDROCHLORIDE 3014-80-0 H-VAL-NH2 HCL USP/EP/BP C5H13ClN2O H-VAL-NH2 HCL 3014-80-0 Butanamide, 2-amino-3-methyl-, hydrochloride (1:1), (2S)- L-Valinamide hydrochloride 3014-80-0 3014-80-8 C5H13ClN2O C5H13N2OCl CH32CHCHNH2CONH2HCl Specialty Synthesis Peptide Synthesis Valine Amino Acid Derivatives Amino Acids and Derivatives Amino hydrochloride Amino Acid Derivatives Amino Acid Derivatives Amino Acids Peptide Synthesis Valine