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betulonic aldehyde

CAS No.
4439-98-9
Chemical Name:
betulonic aldehyde
Synonyms
Betulonaldehyde;betulonic aldehyde;lup-28-al-20(29)-en-3-one;Lup-20(29)-en-28-al, 3-oxo-;Betulonic aldehyde, 97%, Semi-Synthetic;(1R,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-9-oxoicosahydro-3aH-cyclopenta[a]chrysene-3a-carbaldehyde
CBNumber:
CB83147203
Molecular Formula:
C30H46O2
Molecular Weight:
438.68
MDL Number:
MFCD11707369
MOL File:
4439-98-9.mol
Last updated:2023-05-21 10:59:17

betulonic aldehyde Properties

Melting point 165-166 °C
Boiling point 511.7±33.0 °C(Predicted)
Density 1.037±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMF: 10 mg/ml
form A crystalline solid

betulonic aldehyde price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Iris Biotech GmbH LSB3029 Betulonaldehyde 4439-98-9 1g $263.25 2021-12-16 Buy
Iris Biotech GmbH LSB3029 Betulonaldehyde 4439-98-9 2,5g $398.25 2021-12-16 Buy
Iris Biotech GmbH LSB3029 Betulonaldehyde 4439-98-9 5G $540 2021-12-16 Buy
Iris Biotech GmbH LSB3029 Betulonaldehyde 4439-98-9 10g $810 2021-12-16 Buy
Product number Packaging Price Buy
LSB3029 1g $263.25 Buy
LSB3029 2,5g $398.25 Buy
LSB3029 5G $540 Buy
LSB3029 10g $810 Buy

betulonic aldehyde Chemical Properties,Uses,Production

Biological Activity

Betulonaldehyde is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin that has been found in Betula.1 It is active against P. falciparum (IC50 = 3.36 μg/ml) and cytotoxic to NCI H187 lung cancer cells and non-cancerous Vero cells (IC50s = 19.23 and 17.09 μg/ml, respectively).2 Topical application of betulonaldehyde (1 mg/ear) reduces ear edema induced by phorbol 12-myristate 13-acetate in mice.3 It has also been used a precursor in the semisynthesis of C-2 and C-28 betulonic aldehyde derivatives.1

References

1.Ayers, S., Benkovics, T., Marshall, J., et al.Autoxidation products of betulonaldehydeJ. Nat. Prod.79(10)2758-2761(2016) 2.Wisetsai, A., Schevenels, F.T., and Lekphrom, R.Chemical constituents and their biological activities from the roots of diospyros filipendulaNat. Prod. Res.1-5(2019) 3.Yasukawa, K., Yu, S., Yamanouchi, S., et al.Some lupane-type triterpenes inhibit tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skinPhytomedicine1(4)309-313(1995)

betulonic aldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

betulonic aldehyde Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
Dezhou LonWel Pharmaceutical Technology Co., Ltd. 13761310616 39324283@qq.com China 1948 58
Shanghai Standard Technology Co.,Ltd. 021-57127007-6622 15618937986 zhaok@nature-standard.com China 3920 58
ChemeGen 中国 18818260767 sales@chemegen.com China 6975 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1249 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
betulonic aldehyde Betulonic aldehyde, 97%, Semi-Synthetic Betulonaldehyde lup-28-al-20(29)-en-3-one Lup-20(29)-en-28-al, 3-oxo- (1R,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-9-oxoicosahydro-3aH-cyclopenta[a]chrysene-3a-carbaldehyde 4439-98-9