ChemicalBook >> CAS DataBase List >>4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester

4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester

4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester structure

CAS No.: 1941177-45-2

Chemical Name:: 4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester

Synonyms: Palbociclib-020;Palbociclib Impurity 50;1-Piperazinecarboxylic acid, 4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-, 1,1-dimethylethyl ester;4-?[6-?[(8-?Cyclopentyl-?6-?ethenyl-?7,?8-?dihydro-?5-?methyl-?7-?oxopyrido[2,?3-?d]?pyrimidin-?2-?yl)?amino]?-?3-?pyridinyl]?-1-?Piperazinecarboxylic Acid 1,?1-?Dimethylethyl Ester

CBNumber:: CB83154856

Molecular Formula:: C29H37N7O3

Molecular Weight:: 531.65

MDL Number:: MFCD28359442

MOL File:: 1941177-45-2.mol

Last updated:2023-04-23 13:52:06

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4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester Properties

Melting point	>220°C (dec.)
storage temp.	Amber Vial, -20°C Freezer, Under inert atmosphere
solubility	Dichloromethane (Slightly, Heated), DMSO (Slightly, Heated, Sonicated)
form	Solid
color	Light Yellow to Dark Beige
Stability	Light Sensitive

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338

4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	C992563	4-[6-[(8-Cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-PiperazinecarboxylicAcid1,1-DimethylethylEster	1941177-45-2	1mg	$165	2021-12-16	Buy

Product number	Packaging	Price	Buy
C992563	1mg	$165	Buy

4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester Chemical Properties,Uses,Production

Uses

4-?[6-?[(8-?Cyclopentyl-?6-?ethenyl-?7,?8-?dihydro-?5-?methyl-?7-?oxopyrido[2,?3-?d]?pyrimidin-?2-?yl)?amino]?-?3-?pyridinyl]?-1-?Piperazinecarboxylic Acid 1,?1-?Dimethylethyl Ester is an impurity of Palbociclib (P139900) an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.

4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester Suppliers

Global( 39)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
Adamas Reagent, Ltd.	400-6009262 16621234537	zhangsn@titansci.com	China	14113	59
Shanghai Kewel Chemical Co., Ltd.	021-64609169 18901607656	greensnown@163.com	China	9911	50
Nanjing XiZe Biotechnology CO., Ltd.	025-58362220 15250997978	1511893459@qq.com	China	7715	55
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9374	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Shanghai XingTai Pharmaceutical Technology co., LTD	15801747407	sales01@suntechpharma.com	China	123	58
Shanghai Nafu Biotechnology Co., Ltd.	021-58952328 13125124762	sale@chemhui.com	China	498	55

Supplier	Advantage
Standardpharm Co. Ltd.	58
BOC Sciences	58
China National Standard Pharmaceutical Corporation Limited	58
Adamas Reagent, Ltd.	59
Shanghai Kewel Chemical Co., Ltd.	50
Nanjing XiZe Biotechnology CO., Ltd.	55
Shanghai Chaolan Chemical Technology Center	58
Amadis Chemical Company Limited	58
Shanghai XingTai Pharmaceutical Technology co., LTD	58
Shanghai Nafu Biotechnology Co., Ltd.	55

1941177-45-2(4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester)Related Search:

Palbociclib Impurity 36 PalBociclib Impurity 27 Palbociclib-007 tert-Butyl 4-(2-nitropyridin-3-yl)piperazine-1-carboxylate Palbociclib

4-[6-(6-BROMO-8-CYCLOPENTYL-5-METHYL-7-OXO-7,8-DIHYDRO-PYRIDO[2,3-D]PYRIMIDIN-2-YLAMINO)-PYRIDIN-3-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Palbociclib-029 8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-6-vinylpyrido[2,3-d]pyrimidin-7(8H)-one Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]- Phosphine oxide, tris (2-methylphenyl)-

Palbociclib-030 tert-butyl 4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate 1-Piperazinecarboxylic acid, 4-(2-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester 5-(piperazin-1-yl)pyridin-2-aMine Palbociclib-012

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one PD 0332991 HCl 5-bromo-4-chloro-N-cyclopentylpyrimidin-2-amine

1of4

Palbociclib Impurity 50 Palbociclib-020 1-Piperazinecarboxylic acid, 4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-, 1,1-dimethylethyl ester 4-?[6-?[(8-?Cyclopentyl-?6-?ethenyl-?7,?8-?dihydro-?5-?methyl-?7-?oxopyrido[2,?3-?d]?pyrimidin-?2-?yl)?amino]?-?3-?pyridinyl]?-1-?Piperazinecarboxylic Acid 1,?1-?Dimethylethyl Ester 1941177-45-2